Final version of our NRG1 MS is out! We uncover a surprising mechanism: the helper NLR NRG1 targets organellar membranes to trigger immunity Great collaborations with @KamounLab, @JiorgosKourelis, @jonathandgjones, @AdamWu9527, and the @Phil_Carella labs! science.org/doi/10.1126/sc…
Freddie King
@freddie-king.bsky.social
PhD in Bozkurt group, Imperial. Synthetic bio 🤝 plant immunity https://scholar.google.com/citations?user=OzTyyRUAAAAJ&hl=en
Very excited to see our recent work on NRG1 organellar targeting now published! It has been a pleasure working with Tarhan on this, combining synthetic biology/genetics with some incredible microscopy 🤝 www.science.org/doi/10.1126/...
A helper NLR channels organellar calcium to trigger plant immunity
Upon activation, plant nucleotide-binding leucine-rich repeat (NLR) immune receptors are known to assemble into oligomeric resistosomes that insert into the plasma membrane, forming calcium (Ca2+)–per...
science.org
A broad-host-range Rhizobium rhizogenes strain enables transient expression across diverse crops and establishes functional assays in faba bean https://www.biorxiv.org/content/10.64898/2026.04.20.719558v1
Proud to share this preprint from Freddie_King and Juan Carlos @AdamWu9527 & @lderevnina labs! AS109-mediated agroinfiltration enables transient expression across non-model plants and positions faba bean as a tractable system for studying disease-resistance
Finally out! A follow-up to our Rhizobium rhizogenes story with @tolgaboz.bsky.social and Lida. We hope this work will make it easier to study many other plant species. www.biorxiv.org/content/10.6...
Finally out! A follow-up to our Rhizobium rhizogenes story with @tolgaboz.bsky.social and Lida. We hope this work will make it easier to study many other plant species. www.biorxiv.org/content/10.6...
biorxiv.org
Excited to share our preprint using Rhizobium rhizogenes AS109 for agroinfiltration, facilitating strong transient expression across non-model plants including sweet potato, mustard, Medicago and faba bean! doi.org/10.64898/202... 1/7
doi.org
I finally got around to publishing my MPMI poster on 'Developing broad bean as a new model system for studying plant immunity'! We show that you can do HR assays, transient RNAi, and confocal microscopy in this legume species 🌱🫘 Check it out: zenodo.org/records/1631... #2025MPMI
Developing broad bean as a new model system for studying plant immunity
The study of molecular plant immunity using transient Agrobacterium-mediated expression is currently reliant on two key model species, Nicotiana benthamiana and Arabidopsis thaliana. Whilst these spec...
zenodo.org
Plz RT. We are looking for a postdoc to join our collborative project on AI-guided bioengineering of plant immune receptors @tolgaboz.bsky.social and @jiorgoskourelis.bsky.social labs: www.jobs.ac.uk/job/DNV032/r...
Research Associate in Programmable Plant Immunity at Imperial College London
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jobs.ac.uk