Our work exploring host-microbial co-metabolism of bile acids in patients with alcohol-related liver disease (ALD) has been published in the JHEP Reports: www.sciencedirect.com/science/arti... 🪐 A big thank you to everyone involved, to the GALAXY and MicrobLiver consortia who made this possible! 🙌

Alcohol-related liver disease disrupts bile acid homeostasis and gut microbial bile acid metabolism

Alcohol overuse disrupts liver function and alters gut microbial communities, with alcohol-related liver disease (ALD) causing half of all liver-relat…

sciencedirect.com

New in @natgenet.nature.com: a moving obituary for Peer. Francesca Ciccarelli, Jan Korbel & Christian von Mering reflect on his scientific vision, from protein domains and genome evolution to metagenomics, and on his generosity as a mentor and friend to so many. www.nature.com/articles/s41...

Peer Bork (1963–2026) - Nature Genetics

Nature Genetics - Peer Bork (1963–2026)

nature.com

Our study describing `microntology` and annotations for >300k metagenomes is now online in Bioinformatics @academic.oup.com : academic.oup.com/bioinformati... Congratulations to @fullam.bsky.social @vishnuprasoodanan.bsky.social & @biocs.bsky.social ! See the thread below for more details.

microntology: a lightweight, data-driven controlled vocabulary to describe Earth’s microbial habitats

AbstractMotivation. Data-enabled studies of microbial ecology and evolution depend on high-quality descriptions of microbial habitats, based on curated and

academic.oup.com

Sebastian Schmidt@tsbschm.bsky.social · 7mo ago

We just released a @biorxivpreprint.bsky.social describing the *microntology*, a lightweight controlled vocabulary that we have been using for a while to tag metagenomes with contextual data. Study by @fullam.bsky.social @vishnuprasoodanan.bsky.social et al: 1/ www.biorxiv.org/content/10.6...

GUNC pre-processed databases are now also on zenodo thanks to @fullam.bsky.social : zenodo.org/records/1963...

Sebastian Schmidt@tsbschm.bsky.social · 5mo ago

@fullam.bsky.social has pushed a new #GUNC release, v1.1.0: github.com/grp-bork/gun... It fixes some bugs, updates some underlying databases and brings new features (e.g. you can now BYODB – bring your own database). GUNC v1.1.0 is also live on #bioconda .

Due to some IT problems, the Bork group homepage and various services such as SPIRE and Metalog are unfortunately going to be unavailable for a couple of days. We're sorry for that and hope that the outage can soon be resolved!

@fullam.bsky.social has given the SPIRE website a bit of an overhaul: improved pages, nice new options to navigate, improved search, streamlined genome, study and sample pages, tidied up Downloads page, etc. Go check it out: spire.embl.de

Our work on 'hidden diversity' in unbinned contigs is now published in @natmicrobiol.nature.com : www.nature.com/articles/s41... See the linked threads for more details!

Unbinned contigs expand known diversity in the global microbiome - Nature Microbiology

Re-analysis of over 92,000 metagenomes reveals hundreds of thousands of previously undescribed Bacterial and Archaeal clades hidden in plain sight.

nature.com

Sebastian Schmidt@tsbschm.bsky.social · 9mo ago

We've updated our recent @biorxivpreprint.bsky.social on 'Hidden but discoverable diversity in the global microbiome', led by @vishnuprasoodanan.bsky.social & @omaistrenko.bsky.social www.biorxiv.org/content/10.1...

There is a lot of undescribed prokaryotic diversity in existing whole-genome metagenomic data! www.nature.com/articles/s41...

Unbinned contigs expand known diversity in the global microbiome - Nature Microbiology

Re-analysis of over 92,000 metagenomes reveals hundreds of thousands of previously undescribed Bacterial and Archaeal clades hidden in plain sight.

nature.com

@fullam.bsky.social has pushed a new #GUNC release, v1.1.0: github.com/grp-bork/gun... It fixes some bugs, updates some underlying databases and brings new features (e.g. you can now BYODB – bring your own database). GUNC v1.1.0 is also live on #bioconda .

It has been two weeks since the unexpected death of Peer Bork, and all of us in his research group are deeply missing him. His scientific vision brought us together as a team, and we are immensely grateful for the time we spent together. 🧵

EMBL@embl.org · 7mo ago

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond. We extend our deepest condolences to his family, friends, and colleagues. www.embl.org/news/people-...

GUNC v1.0.6 has just been released! This version is a minor release with some small bugfixes and a fix for compatibility with pandas v2. Changelog here: gunc.embl.de/changelog.html The next release is already underway - with more substantial feature additions.