Gene Center Munich @LMU Munich
@genecenter-lmu.bsky.social
Science beyond disciplines — pioneering research in genome biology, immunology, virology & oncology www.genzentrum.lmu.de Official account of the Gene Center Munich, a central scientific institution @lmumuenchen.bsky.social Impressum: tinyurl.com/59k5d95t
🥳 Amazing publication from @jaelab.bsky.social: Mitochondria act as sensors for an essential iron-containing molecule. They uncovered a mechanism that has monitored cellular heme concentrations for more than 700 million years www.nature.com/articles/s41... The team clearly had fun along the way😉
‼️📢📣Only a few days left to apply - don't miss this opportunity!👇
Gene Center Munich @LMU Munich@genecenter-lmu.bsky.social · 4w ago📣 The Cluster for Nucleic Acid Sciences and Technologies is seeking three independent group leaders - one of the positions will be based at the LMU Gene Center🤗 Apply now! ▶️ www.nature.com/naturecareer...
Thrilled to see our paper on CAR-T cells and STING agonists in PDAC highlighted by @aga-gastro.bsky.social today! Very grateful to the brilliant and inspiring @v-hornung.bsky.social for his mentorship and scientific vision throughout this work. @lmu-klinikum.bsky.social @genecenter-lmu.bsky.social
@aga-gastro.bsky.social · 2w agoStudy finds that STING-deficient CAR-T cells + diABZI boost antitumor activity, increase CAR-T persistence, and improve tumor control in pancreatic cancer models, highlighting a potential new strategy for solid tumors. 🔗 https://ow.ly/JVzg50Zq3PM
📣 The Cluster for Nucleic Acid Sciences and Technologies is seeking three independent group leaders - one of the positions will be based at the LMU Gene Center🤗 Apply now! ▶️ www.nature.com/naturecareer...
Independent Group Leader at NUCLEATE Excellence Cluster - Munich or Würzburg job with NUCLEATE Cluster | 12861192
Independent Group Leader in Nucleic Acid Sciences and Technologies within the NUCLEATE Cluster at LMU Munich, TU Munich or JMU Würzburg.
nature.com
NUCLEATE Cluster@nucleate-cluster.bsky.social · 4w agoThe NUCLEATE Cluster of Excellence is hiring! Shape the future of nucleic acid sciences 🧬 🚀 Group Leaders: All 3 locations (LMU, TUM, JMU Würzburg) 🔬 PhDs & Postdocs: Open call in Würzburg and speculative applications welcome! Deadline: Aug 16, 2026 👉 More info: nucleate-cluster.de/careers/
😀We are delighted to announce a special lecture given by ⭐Nobel Prize Laureate⭐ Brian Kobilka ⭐(Stanford University) on Thursday, July 2 at 3:15 pm in the Lynen Lecture Hall: The role of protein dynamics in G protein coupled receptor signaling 🤗We warmly invite you to attend
Great to see the NUCLEATE Cluster of Excellence now on bsky! 🚀 Bringing together leading researchers across disciplines to pioneer the future of nucleic acid science — 🎓🤝@lmu.de @tum.de @uni-wuerzburg.de Excited to follow the journey - make sure to connect 👇
NUCLEATE Cluster@nucleate-cluster.bsky.social · last mo.Welcome to the official account of the NUCLEATE Cluster of Excellence👋🧬 We’re building a community around nucleic acid sciences and technology, and innovation 🚀 Expect research highlights, collaborations, events, and opportunities — with open positions coming soon. #Biotech #Science #RNA #Research
TODAY👇 🕐 2:30 pm ➡️ Römer Lecture Hall, K00.015, BioSysM
Gene Center Munich @LMU Munich@genecenter-lmu.bsky.social · 2mo ago🤩 Another great event this Monday is a workshop on Research Integrity, presented by Inke Näthke. More info: www.genzentrum.uni-muenchen.de/news-events/... 📅 June 22 🕐 2:30 PM ➡️ Römer Lecture Hall, K00.015, BioSysM Everyone is welcome 🤗 @jp-lab.bsky.social
TODAY 👇 🕐 1:15 PM ➡️Lynen Lecture Hall
Gene Center Munich @LMU Munich@genecenter-lmu.bsky.social · 2mo agoJoin us this Monday for a talk by Bill Earnshaw (University of Edinburgh): “Dis-solving the mechanisms of mitotic chromosome formation.” 📅 June 22 🕐 1:15 PM ➡️Lynen Lecture Hall We’re very much looking forward to welcoming him — everyone is invited!🤗 @jp-lab.bsky.social @edinburgh-uni.bsky.social
🤩 Another great event this Monday is a workshop on Research Integrity, presented by Inke Näthke. More info: www.genzentrum.uni-muenchen.de/news-events/... 📅 June 22 🕐 2:30 PM ➡️ Römer Lecture Hall, K00.015, BioSysM Everyone is welcome 🤗 @jp-lab.bsky.social
Join us this Monday for a talk by Bill Earnshaw (University of Edinburgh): “Dis-solving the mechanisms of mitotic chromosome formation.” 📅 June 22 🕐 1:15 PM ➡️Lynen Lecture Hall We’re very much looking forward to welcoming him — everyone is invited!🤗 @jp-lab.bsky.social @edinburgh-uni.bsky.social
We look forward to welcoming Jan-Michael Peters next Monday. Besides talking to our PIs, he will give a lecture entitled "How cohesin folds the genome by loop extrusion". 📅 June 15 🕐 1:15 PM ➡️Lynen Lecture Hall 🤗 Join us for an inspiring talk! @jstingele.bsky.social @impvienna.bsky.social
TODAY👇
Gene Center Munich @LMU Munich@genecenter-lmu.bsky.social · 4mo ago🤗We're excited to host Agnel Sfeir next Monday! She will give a talk on “Two Genomes, One Balance: Mitochondrial and Nuclear DNA Stability” 📅 April 27 🕐 1:15 PM ➡️Lynen Lecture Hall Join us for an inspiring talk – see you there! @agnelsfeir.bsky.social @jstingele.bsky.social
📣Don't miss this job posting: The lab of Eckhard Wolf at the Gene Center @lmu.de is looking for a PhD student for the Molecular Characterisation of a Pathogenic KCNJ5 Mutation and its Effect on the Adrenal Gland www.genzentrum.uni-muenchen.de/career/wolf_... #PhD #PhDcandidate #Phdjobs
PhD position in Molecular Characterisation of a Pathogenic KCNJ5 Mutation and its Effect on the Adrenal Gland (f/m/x) - Gene Center Munich - LMU Munich
genzentrum.uni-muenchen.de
🤗We're excited to host Agnel Sfeir next Monday! She will give a talk on “Two Genomes, One Balance: Mitochondrial and Nuclear DNA Stability” 📅 April 27 🕐 1:15 PM ➡️Lynen Lecture Hall Join us for an inspiring talk – see you there! @agnelsfeir.bsky.social @jstingele.bsky.social
Two inspiring days at our Gene Center Retreat in Kloster Irsee! 🧐 Our PIs, PhD candidates and postdocs shared exciting insights into their latest research 🤩 Special highlight: talk by @hillermich.bsky.social, who gave a fascinating perspective on bats and their adaptations to a blood-based diet 🩸 🦇
A huge success! 🏆 In the latest edition of the #QSWorldUniversityRankingsbySubject LMU Munich was recognized as one of the world’s leading universities for 36 subject areas and ranks first in Germany in #seven of them. Read more here: www.topuniversities.com/subject-rank...
Come and join Nobel laureate Paul Nurse, President @royalsociety.org, and philosopher Christof Rapp @caslmu.bsky.social @lmu.de in exploring one of the most fundamental questions in science: What is Life? Save the date: 17 April, 16:15📍LMU, main building register: info@cas.lmu.de, www.cas.lmu.de
🥳 Karl-Peter Hopfner has been elected as a full member of the Bavarian Academy of Sciences and Humanities. He is among 13 newly elected scientists recognized for their outstanding research. 👏 😃 Congratulations! 👏 badw.de/die-akademie... @badw.de @hopfnerlab.bsky.social
📣Publication alert: Julian Stingele and his team show that the chemotherapeutic drug azacitidine damages RNA and reveal a possible approach to improve therapies🤩👏 www.sciencedirect.com/science/arti... @jstingele.bsky.social @lmu.de @shubozhao.bsky.social
RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response
Excessive RNA damage activates cellular stress responses, triggering cell death. However, pathways that negatively regulate RNA damage responses are l…
sciencedirect.com
LMU News about ERASE-ML @msubklewe.bsky.social New hope for people with leukemia and prostate cancer www.lmu.de/en/newsroom/...
New hope for people with leukemia and prostate cancer
Two Bavaria-wide studies are receiving millions in funding to enable cancer patients in Bavaria to get access to innovative diagnostic procedures and treatments at an early stage.
lmu.de
🏆 LMU Munich remains at the forefront: Status as #UniversityofExcellence confirmed – as decided by an international jury within the framework of the Excellence Strategy of the German federal and state governments. Read more here:
LMU Munich remains at the forefront: Status as University of Excellence confirmed
Within the framework of the nationwide Excellence Strategy of the German federal and state governments, LMU has once again successfully asserted itself, further consolidating its status as one of Euro...
lmu.de
📣Excited to share breakthrough work🚀 from @msubklewe.bsky.social and the LMU Hospital team: their bispecific antibody therapy targets disease-causing B cells, offering new hope for treatment-resistant ITP and APS—all without chemotherapy🤩 ➡️New England Journal of Medicine www.nejm.org/doi/full/10....
Blinatumomab in Combined Immune Thrombocytopenia and Antiphospholipid Syndrome | NEJM
A CD19-targeted therapy induced remission in a woman with refractory immune thrombocytopenia and antiphospholipid syndrome by stabilizing platelet counts, eliminating pathogenic antibodies, and ena...
nejm.org
📣 @msubklewe.bsky.social and Veit Bücklein lead EASE-AML, a novel cell therapy for aggressive leukemia👏 Funded with €3 million, ERASE-AML is one of the two newly launched clinical trials supported by the Bavarian Cancer Research Center (BZKF). Congratulations, Marion!🥂🥳
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Nucleic Acids Research@narjournal.bsky.social · 5mo ago🎉 Congratulations to the first authors, Priyanka Aggarwal and Manmohan Sharma! Their study in the laboratory of Prof. Karl-Peter Hopfner provides important #mechanistic insight into #chromatin #remodeling across diverse #nucleosomalstates. 🧬🔬 #NARbreakthrough #Chromatin #Epigenetics #INO80
🥳Big shout out to the @hopfnerlab.bsky.social, amazing paper!🤩
Nucleic Acids Research@narjournal.bsky.social · 5mo ago⭐NAR Breakthrough! ⭐ 🧬 New #cryo-EM work shows the #humanINO80 motor adapts to DNA unwrapping and can remodel altered particles like #hexasomes - highlighting its versatility across #nucleosome states. 🔬✨ @lmu.de @genecenter-lmu.bsky.social Read the full article here: doi.org/10.1093/nar/...
➡️In a recent interview with Süddeutsche Zeitung, our PI Eckhard Wolf discusses the remarkable progress made in xenotransplantation. sz.de/li.3385188
Xenotransplantation: Wann können Organe von Tieren Menschen retten?
Nach erfolgreichen Transplantationen von Schweineherzen, -nieren und -lungen gibt es neue Hoffnung für Patienten. Genetische Modifikationen und Forschung lösen alte Probleme.
sz.de
🏛️ 200 Years of LMU in Munich 🎓 Founded in 1472, relocated from Landshut to Munich in 1826 — today LMU celebrates 200 years in Munich and inaugurates Prof. Dr. Matthias H. Tschöp as President.
🥳And here’s the next publication from the Bohlen Lab — congratulations!👏
Jonathan Bohlen@jonathanbohlen.bsky.social · 6mo agoNew paper in the Journal of Human Immunity! We report complete and partial forms of X-linked MCTS1 deficiency in patients with mycobacterial disease -- four new families from Iran, Oman, China, and the USA. doi.org/10.70962/jhi...
🌟Don' t miss this article about personalized cancer therapy featuring our PI, Marion Subklewe www.lmu.de/en/about-lmu... @msubklewe.bsky.social
Cancer therapy made to measure
Marion Subklewe and Sebastian Kobold are getting the immune system to target tumors and opening up new perspectives for patient-specific treatments.
lmu.de