🎉 Proud of our colleague for successfully defending his PhD thesis yesterday. So much work and heart behind it. Congratulations Dr. Javier Isoler Alcaraz! Thanks to the committee @vaquerolab.bsky.social, Maria Villa Morales and @davidlandeira.bsky.social for an engaging and enriching discussion!

Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social www.biorxiv.org/content/10.6...

Our preprint describing the moonlighting functions of SEC13 in NMD and regulation of the UPR is out now in bioRxiv www.biorxiv.org/cgi/content/...

Our new paper is finally out! 📢 Great team effort from Sara M, @joanasgrmrtnz.bsky.social and @agalleg.bsky.social with the support from everyone in the lab. Many thanks to our collaborators, @andreichabes.bsky.social , @mmaslon.bsky.social and @lschermelleh.bsky.social

Slow RNAPII elongation enhances naive pluripotency rewiring while maintaining high replication fork speed

Slowing RNAPII velocity boosts naive pluripotency, uncovering an unexpected link to cell plasticity.

science.org

Congrats to the whole team!

Carlos Estella@estella-carlos.bsky.social · 4mo ago

Some of these mechanisms are also recapitulated by human p53 versions when expressed in Drosophila cells, suggesting broader relevance beyond the fly system. 9/9 Read the paper here: www.nature.com/articles/s41...

Members of the Lab, with other PhD students and postdocs from @cbm-csic-uam.bsky.social, had an inspiring conversation with Dr. Juan Méndez (cniostopcancer.bsky.social) on what PIs expect from new postdocs and academic career opportunities. A truly enriching exchange! ✨

Superinspiring!-as always

The Francis Crick Institute@crick.ac.uk · 5mo ago

“I think it’s a real mistake to forget where the pipeline for all this begins.” John Diffley reflects on the importance of basic research, his mission to decode DNA replication and recreate it in the lab, and the scientific optimism of the 1960s that helped shape it. www.crick.ac.uk/news/2026-03...

Happy to share our first preprint! Led by @joseruiziglesias.bsky.social — EpiFlow: multidimensional single-cell epigenetic profiling by spectral flow cytometry Many thanks to @cbm-csic-uam.bsky.social, @ageinves.bsky.social and Fundación Ramón Areces for their support www.biorxiv.org/content/10.6...

Our postdoctoral researcher @joanasgrmrtnz.bsky.social, together with other researchers from @cbm-csic-uam.bsky.social, has participated in the video by @contracancerinv.bsky.social to commemorate **Women’s Day (#8M)** to recognize the strength, dedication and talent of women in science 💜

Superb science and great atmosphere! It is a pleasure to attend the R2G2 meetings!

Centro de Biología Molecular Severo Ochoa@cbm-csic-uam.bsky.social · 5mo ago

The 2nd Genomic Regulatory Network Annual Meeting, organised by the CBM & funded by @AgEInves, is a great success. Over 3 days, researchers are sharing exciting results, building collaborations, and strengthening connections across institutions. @csic.es @uam.es

We go live!!! Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field AND !! registration is FREE 🥳 (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social @replifate.bsky.social @epicrossborders.bsky.social replifate.eu/event/meetin...

Events for February 2026

06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding how DNA replication...

replifate.eu

Particularly excited to announce "In Formation" 👉Vernissage 17h00 Munich *5th of July* @Muffatwerk 1st exhibition of Art&Science work from 4 artists, including annadumitriu.co.uk + @replifate.bsky.social Helen Pynor,Solveig Lill & Pei-Ying Lin replifate.eu/event/in-for... 😇STAY TUNED 4more info

Events for February 2026

We are thrilled to announce In Formation, the first exhibition featuring work from four artist-in-residence projects that bring art into the heart of scientific stem cell and epigenetics research. ...

replifate.eu

Celebramos el #11F con una foto de nuestras compañeras científicas, técnicas, gestoras, etc., en el CBM. 👩‍🔬💫 ¡Por más visibilidad, igualdad y oportunidades para las mujeres en ciencia! #MujeresYCiencia #diadelamujerylaninaenlaciencia #TodasHacemosCiencia

Orgullosa de formar parte de la red de investigadoras de la Fundación @contracancerinv.bsky.social #investigadorascontraelcancer

¿Aún no eres miembro de la SEBBM? Recuerda que serlo te permite tener también otras ventajas adicionales y supone serlo también de FEBS y de IUBMB con todo lo que ello conlleva de acceso a formación e información. https://f.mtr.cool/rufsraevpc

In the Chromatin, cancer and the ubiquitin system lab, we are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva call (3 years) www.aei.gob.es/en/announcem...

We are looking for a candidate to apply for a postdoctoral contract in the Juan de la Cierva 2025 call, to join our lab at the @cbm-csic-uam.bsky.social to work on the interplay between the ubiquitin pathway, DNA replication and the replication stress response. #JDC2025

📢¡Oferta de trabajo en el CBM! El grupo de César Cobaleda busca postdoc para estudiar cómo se origina la leucemia infantil (B-ALL). 💡 Proyecto “la Caixa” Research Health 2025 🧬 Modelos murinos, epigenética, célula única 📅 Deadline: 5 dic 2025 www.cbm.uam.es/index.php/jo... @cjchcm.bsky.social

Molecular Mechanisms of Childhood Leukemia Development - Centro de Biología Molecular Severo Ochoa

Job Description We are seeking a highly motivated postdoctoral researcher to join our laboratory to study the early steps of development of childhood B-cell Acute Lymphoblastic Leukemia (B-ALL). The p...

cbm.uam.es

🗓️Próximo "Webinar Grupo regulación de la expresión génica y dinámica del genoma" coordinado por María Gómez Vicentefranqueira 🗣️Leonardo Beccari - investigador RyC, CBM ✍️ https://f.mtr.cool/zthcqvnbgo ▶️ https://f.mtr.cool/ijmaqtygnc

Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team! Please repost! jobs.jic.ac.uk/Details.asp?...

Todas las sesiones del Golden Jubilee Symposium: Fifty Years of Discovery, con el que celebramos nuestro cincuentenario, están disponibles ya en nuestro canal de YouTube. Charlas, mesas redondas y acto institucional, en esta lista 👇📺 youtube.com/playlist?lis...

CBM Golden Jubilee Symposium - YouTube

youtube.com

The @cbm-csic-uam.bsky.social has celebrated its Golden Jubilee with two days filled with inspiring talks. We had the joy of hearing from outstanding scientists — including Nobel Prize laureates and leading figures in molecular biology — we were truly honored to have spoken with Dr. Svante Pääbo

Scientists reflected on running DNA.

🎥🔬 50 años descodificando la vida. Descubre en este video cómo el CBM ha marcado la biomedicina en España y el mundo, formando talento y generando ciencia de impacto. #CincuentenarioCBM #DecodingLife youtu.be/7bzJOIW5kyM

Cincuentenario del Centro Biología Molecular Severo Ochoa - Decoding life

YouTube video by Centro de Biología Molecular Severo Ochoa

youtu.be

🧠⚡ ¡La Sección Junior estrena concurso! 🔬 "Sinapsis en Juego"  📅 27 sept ( por la mañana) - Zoom 👥 Equipos de 3 (al menos 1 soci@ SEBBM) 🏆 Premios para el equipo ganador 👉 Inscríbete antes del 23/9 ¿Aceptas el reto? 😏 + info: https://f.mtr.cool/rrqtyiwjaa

🎉 ¡Ya tenemos ganadores! Adrian de Reus @cbm-csic-uam.bsky.social y Andrea Sampere @cbgpmadrid.bsky.social se llevan un ejemplar de #SerCientífico, el último libro de @lluismontoliu.bsky.social, compañero de la #SEG. 🙌 ¡Gracias por la generosa donación, Lluis!

Join us! Great line up of speakers on an interesting topic! Thanks to @csic.es Conexion GENOMA for making it possible #TEsky @sesbe-org.bsky.social @sebbm.bsky.social @segenetica.bsky.social @droseu.bsky.social

Sònia Garcia@sphaeromeria.bsky.social · 11mo ago

Interested in repetitive DNA? We are organising a free workshop on Oct 2nd at the Botanical Institute of Barcelona! All organisms included - not only plants ;-) Last chance for registration, don’t miss it! bit.ly/repetitiveDN...

🔬Thrilled to present our Xenium results in brain from obese mice together with my lab mate, Hugo NG Martin, at the Leipzig-Halle Spatial Biology Network Symposium🧠 🐁

Fantástica sesión del grupo "Regulación de la Expresión Génica y Dinámica del Genoma" en la preciosa Cáceres #47congresoSEBBM. Gracias a todos los speakers y participantes!!

👉ASEICA reclama➕financiación ante la resolución provisional de la Convocatoria de Proyectos Generación de Conocimiento 2024 @cienciagob.bsky.social ha publicado la resolución provisional de la convocatoria 2024 de Proyectos I+D Gráfica: @jaestebancbm.bsky.social ℹ️ www.aseica.es/aseica-recla...

ASEICA reclama más financiación ante la resolución provisional de la Convocatoria de Proyectos Generación de Conocimiento 2024

El Ministerio de Ciencia, Innovación y Universidades, a través de la Agencia Estatal de Investigación ha publicado la resolución provisional de la convocatoria 2024 de Proyectos I+D. Según aseguran ...

aseica.es