Our paper describing the role of SEC13 in NMD and regulation of the stress response has now been published in RNA rnajournal.cshlp.org/content/earl...

Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social www.biorxiv.org/content/10.6...

Excited to highlight the new Special Issue of RNA showcasing advances in system-level RNA biology, from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond #RNAbiology #Epitranscriptomics #RNAseq #ComputationalBiology #Genomics bit.ly/4tEQL9I

This will be a great way to celebrate the achievements of MRC Human Genetics Unit PhD students - both current and past. Please share far and wide!

Wendy Bickmore@wbickmor.bsky.social · 5mo ago

Calling all alumni of the MRC Human Genetics Unit Join us on Wednesday 23rd Sept to mark the last ever intake of PhD students to the HGU, and to celebrate the achievements of our alumni, and current PhD cohort. To secure a place, please registerat: www.eventbrite.co.uk/e/mrc-hgu-ph...

Our preprint describing the moonlighting functions of SEC13 in NMD and regulation of the UPR is out now in bioRxiv www.biorxiv.org/cgi/content/...

Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...

Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome

UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...

cell.com

A drug candidate for hard-to-treat cancers, developed by Profs Neil Carragher and Asier Unciti-Broceta at #IGC and licensed to Nuvectis Pharma, has moved to the next stage of clinical trials. Read more here: edin.ac/3UuvJeo @edinnovations.bsky.social

Life-saving cancer drug takes next step in clinical development | Institute of Genetics and Cancer | Institute of Genetics and Cancer

A drug candidate for hard-to-treat cancers, developed in the Institute of Genetics and Cancer (IGC) and now licensed to Nuvectis Pharma, has moved to the next stage of clinical trials after successful...

edin.ac

Congratulations to David Tollervey! He received this year's RNA Society Lifetime Achievement in Science Award. @rnasociety.bsky.social

Join us in San Diego. A great meeting and also featuring the RNA Journal

AAnita Corbett@acorbe2.bsky.social · 2y ago

Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January RNASociety Note the fabulous artwork by former EmoryBCDB student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025

Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬

Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape - Genome Biology

Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...

link.springer.com

Looking for a new home to share all things RNA. That other place was just too crazy. Excited to see so many old RNA friends here on this platform! #RNA

New EdiRNA events for the new year! Funded by the @RNASociety. Great opportunity to network with other RNA biologists 🧬 (dsRNA included) from Edinburgh and beyond 🚀 Jan 29, 2025 Apr 9, 2025 Jun 11, 2025 Oct TBD, 2025 www.edirna.com/meetings