Find out more about our Call for Papers on #Ageing, #Healthspan and #Lifespan and our other open Calls! physoc.onlinelibrary.wiley.com/hub/journal/... @physoc.bsky.social @apspublications.bsky.social @wileylifesci.bsky.social #Physiology

physoc.onlinelibrary.wiley.com

The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch doi.org/10.7554/eLif...

The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch

Titin-associated muscle ankyrin repeat proteins limit stretch-induced longitudinal muscle hypertrophy and link titin mechanosensing to mTOR signaling.

doi.org

One arm in a cast? Training the other may help keep it strong🤯 Surprisingly, a new review in Journal of Applied Physiology finds working the opposite arm may preserve strength and muscle size in the immobilized one: https://ow.ly/yhzf50Zs4cv APS Publications #ArticlesInPress 🧪 📷: iStock

As Fall approaches, many early career scholars will enter the faculty job market. A new JAB article offers practical guidance on preparing applications, interviewing, and evaluating offers. You don't want to miss this free-access resource! 📝 doi.org/10.1123/jab.... #AcademicCareers #Biomechanics

Muscle mass and denervation explain variability in maximal power and rapid force across the adult female lifespan https://www.biorxiv.org/content/10.64898/2026.07.13.738367v1

Congratulations to Dr. Kiisa Nishikawa @kiisa.bsky.social on delivering the Animal Section Plenary Lecture at the Society for Experimental Biology @sebiology.bsky.social Annual Conference in Florence as the recipient of the 2026 SEB Bidder Lecture Award! #SEB2026 #ExperimentalBiology

Multifactorial nature of anabolic resistance in ageing skeletal muscle: A systems modelling study physoc.onlinelibrary.wiley.com/doi/10.1113/...

Multifactorial nature of anabolic resistance in ageing skeletal muscle: A systems modelling study

Abstract figure legend We leveraged a kinetic model of muscle protein metabolism to investigate the multifactorial drivers of age-related anabolic resistance. Literature-derived putative mechanisms o...

physoc.onlinelibrary.wiley.com

Muscle Satellite Cells and Aging journals.physiology.org/doi/abs/10.1...

Muscle Satellite Cells and Aging | American Journal of Physiology-Cell Physiology | American Physiological Society

Aging is associated with a progressive decline in skeletal muscle mass and function, contributing to reduced physical capacity in older adults. Central is the deterioration of satellite cells, our tis...

journals.physiology.org

Muscle in Fat Trouble: The Rise of IMAT in Metabolic and Musculoskeletal Disease www.sciencedirect.com/science/arti...

Microgravity-Induced Muscle Atrophy in Rodent and Human Models www.sciencedirect.com/science/arti...

Isometric slow- and fast-contracting skeletal muscle fibres have more similar cellular and molecular properties at 37°C than at 25°C in older adults physoc.onlinelibrary.wiley.com/doi/10.1113/...

Isometric slow‐ and fast‐contracting skeletal muscle fibres have more similar cellular and molecular properties at 37°C than at 25°C in older adults

Abstract figure legend Physiological temperature imparted more profound changes to cross-bridge kinetics and cross-bridge binding in slow-contracting fibres, leading them to have more similar contrac...

physoc.onlinelibrary.wiley.com

🌟 Postdoc position open at Karolinska Institutet to advance research on healthy aging 🔬 🧫 See here: lengefeldlab.com Please RT! We are excited for your applications 😄

Latest from the lab ⚠️ 📢 🚨

Geoff Power@geoffpower.bsky.social · 4w ago

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats - Kirkup - Experimental Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.1113/...

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats - Kirkup - Experimental Physiology - Wiley Online Library physoc.onlinelibrary.wiley.com/doi/10.1113/...

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats

Serial sarcomere number (SSN) is reduced following immobilization of a muscle in a shortened position in male rodents thereby impairing muscle contractile function. However, in female rodents the eff....

physoc.onlinelibrary.wiley.com

Delighted to see this paper finally published. New insights into the impact of aging on the human NMJ (hint: it’s NOT denervation!): JCI - Neuromuscular junction failure in sarcopenia is linked to NaV1.4 loss and reversed by ClC-1 inhibition www.jci.org/articles/vie...

Emerging Mechanisms Associated with Disuse-Induced Skeletal Muscle Atrophy www.sciencedirect.com/science/arti...

André Tomalka et al. (@unistuttgart.bsky.social, University of Rostock) discuss the effects of chemical myosin II cross-bridge inhibitors on eccentric force production in skinned muscle fibres 📖 buff.ly/M20OmCV

Unimanual fatigue increases muscle excitation and local metabolic activity in the resting contralateral forearm https://www.biorxiv.org/content/10.64898/2026.06.30.735603v1

Is watching the #FIFAWorldCup bad for your health? That's the question our Experimental Physiology Editor-in-Chief, Professor Damien Bailey, and his PhD student, Danny Walmsley, aim to answer by measuring the stress response to an England game. Learn more in this article: bbc.co.uk/news/article...

Is watching England play bad for your health?

Watching football is an emotional rollercoaster - but is it good or bad for your health?

bbc.co.uk

Estrogen-related receptor signaling counters sarcopenia and preserves exercise fitness in naturally aged mice www.biorxiv.org/content/10.6...

Estrogen-related receptor signaling counters sarcopenia and preserves exercise fitness in naturally aged mice

Background Estrogen-related receptor gamma (ERRγ) drives an exercise mimicking aerobic gene program in the skeletal muscle that could be beneficial in aging. We have investigated the effect of chronic...

biorxiv.org

🚨 New original paper by Alexander Zero and Geoffrey Power: Stretch–shortening cycles mitigate single muscle fibre power deficits following a two-week immobilization of the rat hindlimb. #myoblue #work #disuse #force-enhancement #single-fibre doi.org/10.1007/s109...

We are #hiring a Life Science Product Consultant. This position combines technical sales and scientific support to drive sales growth across Europe for our brand of research instrumentation. Learn More 👇 https://aurorascientific.com/about/careers/

a preprint describing the fast and fair system from Biology Open @biologists.bsky.social . Turns out if reviewers get paid they review papers fast and don't ghost the editors' emails. @cdnsciencepub.com you may want to look at it. www.biorxiv.org/content/10.6...

I’ve officially resigned as Associate Editor for Frontiers in Systems Neuroscience. It used to be a reputable journal, but became a case study in how forced automation destroys academic integrity. 👇

Muscle fibre denervation in ageing portlandpress.com/clinsci/arti...

Multicellular senescence impairs skeletal muscle recovery following disuse in aging www.science.org/doi/10.1126/...

Multicellular senescence impairs skeletal muscle recovery following disuse in aging

Senescent interstitial cells accumulate in aged muscle and are related to impaired cellular remodeling.

science.org

😃 In a new article published in J Biomech, Bolsterlee et al. found that muscle fascicles were shorter and PCSAs were smaller in all triceps surae muscles of children with CP, but architectural adaptations vary substantially between muscles and children. 👀https://buff.ly/LCv3di1

Sex-specific effects of fatiguing exercise on skeletal muscle passive mechanics are preserved in aging https://www.biorxiv.org/content/10.64898/2026.05.22.727297v1

Cameron Hill and co-authors from @kingscollegelondon.bsky.social identified distinct distributions of #myosin motor conformations during contraction of slow and fast skeletal #muscle ⚙️ 🔬 📜 Read the study: 🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...

Beyond the first bout: Adaptations to repeated injuries across physiological and pathological conditions physoc.onlinelibrary.wiley.com/doi/10.14814...