bishara marzook
@ghostpathogen.bsky.social
Used to be funny, now i make parasites kiss. Incoming PI at GIMM, working on Cryptosporidiosis: @epi-api-lab.bsky.social (Postdoc at The Francis Crick Institute, UK; PhD at USyd, Australia) Host-pathogen interactions, cytoskeleton, immunity, community.
Today marks 30 years since we identified the apicoplast, a relict plastid in human and animal parasites (PMID 8632819). Apicoplasts are the target of the widely used antimalarial prophylactic doxycycline, which has saved many thousands of malaria infections.
New funding opportunity from the Symbiosis in Aquatic Systems Initiative. We’re inviting teams of two researchers to pursue ambitious, high-risk projects advancing aquatic symbiosis (marine + freshwater). Open globally. Details + how to apply: moore.org/SymbiosisRFP #RFP #AquaticSymbiosis
#WorldHepatitisSummit poster - our team shared #CommunityEngagement experience from our 'EVOLVE' #HBV project in #SouthAfrica to enhance interventions for #hepatitis #elimination. 🧪 👏 #WHS2026 #NoHep #MedSky #LiverSky @ahri-news.bsky.social @uclnews.bsky.social @crick.ac.uk doi.org/10.6084/m9.f...
Really important and relevant study in TB from @danbarberphd.bsky.social and colleagues. We need to re-think many assumptions. Nitric oxide production in mice has been a confounding factor. #tuberculosis
Daniel L. Barber, PhD@danbarberphd.bsky.social · 3mo agoSo we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. rdcu.be/ff9GB #tuberculosis #immunology
Wan’t to be faculty at a collegial host-pathogen focused department in a beautiful bikable city with amazing food? This link is for you: facultycareers-ohsu.icims.com/jobs/39006/a...
New research led @ndeyfa2.bsky.social, a PhD student @lshtm.bsky.social shows #malaria drug resistance isn’t driven by a single mutations but a complex combination of genetic changes that help parasites with legacy mutations survive newer treatments. Read more 👉 bit.ly/49aMu5W
Hi all, I'd like to share some news - I will soon be moving to Lisbon, Portugal to start my very own lab @gimminstitute.bsky.social! The Epithelial Biology of Apicomplexan Infections lab (Epi-Api lab for short) will focus on the special relationship between #epithelial cells and #Cryptosporidium.
The IMPRS-BAC is an outstanding PhD program in Europe. And the endogenous retroviruses in development... what can I say? So much exciting biology to uncover! 🦠🧬#TEsky #StemCells Read the instructions and apply! ⬇️⬇️⬇️
Max Planck Institute for Molecular Genetics@molgen.mpg.de · 8mo agoWant to analyze the role of endogenous retroviruses in early human development or investigate their regulation in pluripotency and early development for your PhD? Join the lab of @fueyoraquel.bsky.social via the IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/5094682/Fuey...
There's still time to register for CoccidiaUK in London - it's going to be a jam-packed two days of talks by early-career parasitologists, a knowledge transfer session, plus trivia and prizes! It's @crick.ac.uk (very central) & we're cooking up some fun swag :) www.eventbrite.co.uk/e/coccidiauk...
CoccidiaUK 2025
A biannual gathering of parasitologists from across the UK to discuss all things coccidian!
eventbrite.co.uk
Who-cysts? OOCYSTS! That's right, it's almost time for ❄️Coccidia UK 2025❄️ Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register- tinyurl.com/4ny5bwu2
CoccidiaUK 2025 registration
DEADLINE FOR ABSTRACT SUBMISSION: NOVEMBER 7th Event Timing: December 8th 9am-5pm December 9th 9am-12pm Event Address: The Francis Crick Institute Questions? please email ada...
tinyurl.com
My background is in molecular microbiology and parasitology, with a focus on malaria drug resistance. I’ve worked across international collaborations, mentored, and published in high-impact journals. Open to research, project-management, or education-focused roles in academia, govt or industry.
I’ve recently been made redundant from my role at UNSW due to the NIH’s decision to cancel foreign subawards. It’s an unfortunate situation affecting a lot of great researchers, and I’m now on the lookout for something new. If anyone knows of any molecular biologist roles coming up, let me know!
We are so excited to see the new avenues for research this will create! 👏👏👏 @ghostpathogen.bsky.social @lottabaumgaertel.bsky.social @netanyabernitz.bsky.social @tapokam.bsky.social @lucy-watson.bsky.social @crick.ac.uk
bishara marzook@ghostpathogen.bsky.social · last yr.Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection phenotypes of the intracellular parasite Cryptosporidium. Hits in the host cholesterol biosynthesis pathway a...
cell.com
Last chance to apply for great research tech #job in my friendly lab @uclmedsci.bsky.social in London! Cutting-edge organoid and microbiology work seeking to understand how probiotic bacteria might be deployed to fight urinary infection #UTI. Closes 23 July #UTISky www.jobs.ac.uk/job/DNQ902/r...
Research Technician at UCL
Apply now for the Research Technician role on jobs.ac.uk - the leading job board for higher education jobs. View details.
jobs.ac.uk
For those interested in Masters in lab and field based research in infectious disease we have 3 fantastic programmes to choose from MSc Immunology, medical parasitology and entomology and medical microbiology. They benefit from very flexible module choices and summer projects in UK and abroad!
London School of Hygiene & Tropical Medicine@lshtm.bsky.social · last yr.👋In person course applications closing soon! Don't miss your chance to join the next generation working to improve #GlobalHealth worldwide.🌍 Apply now for our 2025/26 programmes. 👇 www.lshtm.ac.uk/study/course...
Open call: If you are a researcher working on a project estimating a cause-specific burden of disease attributable to climate change at regional to global scales, please reach out! We're looking for researchers who might be interested in joining a new collaborative network / workshop series.
Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...
I used inducible CRISPR/Cas9 to make Trypanosoma brucei cell line that allowed me to edit originally muti-copy histone gene. We uncovered a novel role of H4 histone tail in gene regulation. I enjoyed working on this exciting project with @joanarcf.bsky.social, a great mentor. doi.org/10.1038/s414...
Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes - Nature Communications
Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses precision gene editing, site-satur...
nature.com
Postdoc position open to investigate chronic Toxoplasma infection! elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic Postdoctoral researcher to join the Young lab to investigate secreted proteins during chronic Toxoplasma gondii infection.
elxw.fa.em3.oraclecloud.com
Very cool work! More proof we have a lot to learn about actin and associated nucleation factors from apicomplexans :)
Freddy Frischknecht@freddyfrischknecht.bsky.social · last yr.Finally published: discovery of an unusual Arp2/3 complex with surprising new function in transmission of #malaria #parasites. Great work by Franzi Hentzschel, Yvonne Sokolowski + David Jewanski + fantastic collaboration with Matthias Marti: www.nature.com/articles/s41...
Honoured to have been invited to give a hallowed GRiP-ing seminar yesterday in Glasgow! Thanks @abhinay.bsky.social for the invite and @uofgsii.bsky.social for hosting me! Now enjoying the classic Glaswegian weather 😁 (yesterday was beautiful though!)
90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO
Omaya Dudin
Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why unicellular organisms evolved multicellularity at the University of Geneva.
cell.com
We are developing a simple, very cheap, low tech way to reduce malaria transmission. Instead of giving the antimalarials to people, we give them to the mosquitoes that spread the parasite. How do we drug a mosquito? Read on. www.sciencedirect.com/science/arti...
Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito
A decade-long decline in malaria cases has plateaued, primarily due to parasite drug resistance and mosquito resistance to insecticides used in bed ne…
sciencedirect.com
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Marc Dionne@marcsdionne.bsky.social · last yr.My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate. www.philanthropy.cam.ac.uk/give-to-camb...
Had a great time at this, learned so much! Thank you again for having a parasitologist amongst you. Looking forward to more host-pathogen interaction interactions 😁
UK Cellular Microbiology@ukcellmicro.bsky.social · last yr.The UK Cellular Microbiology meeting was an incredible success this year! A huge thank you to all the brilliant speakers, poster presenters, and attendees who made this such a dynamic and inspiring event! See you all next year!
Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research. Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...
