gokcen.bsky.social

@gokcen.bsky.social

New preprint! Our workflow for processing single cell and nuclei data, called 🎉 scprocess 🎉 We have been working on it for ~18 months now, over which time we have processed at least 2k samples with it, so it has had a decent amount of testing.

Cute logo for the package scprocess, showing a cartoon of 3 cells being unpacked from a box labelled with a barcode, and loaded onto a conveyor belt. The colour scheme is purple, dark blue and mustard.
#SingleCell preprints@prepub-singlecell.bsky.social · 5mo ago

scprocess: a pipeline for processing, integrating and visualising atlas-scale single cell data #SingleCell 🧪🧬🖥️ https://www.biorxiv.org/content/10.64898/2026.03.09.710141v1

G
G
G

Can DNA sequence models predict mutations affecting human traits? We introduce TraitGym, a curated benchmark of causal regulatory variants for 113 Mendelian & 83 complex traits, and evaluate functional genomics and DNA language models. Joint work w/ Gökcen Eraslan and @yun-s-song.bsky.social 🧵👇

Bild
bioRxiv Genetics@biorxiv-genetic.bsky.social · last yr.

Benchmarking DNA Sequence Models for Causal Regulatory Variant Prediction in Human Genetics https://www.biorxiv.org/content/10.1101/2025.02.11.637758v1