Physiological fatty acid uptake reveals spatial and systemic constraints on nutrient accessibility in vivo https://www.biorxiv.org/content/10.64898/2026.08.14.744781v1
Graham Heieis
@grahamheieis.bsky.social
Immunologist keen to understand the crossroads of immuno-metabolism and tissue responses.
In case you missed it‼️ The wonderful @nickilott.bsky.social from @oxmicrobiome.bsky.social & our lab made an appearance on BBC Radio 4's Sliced Bread last week!📻 The episode gives a great run down on gut microbiome testing kits🦠🧑🔬 Catch up on the episode here! www.bbc.co.uk/sounds/play/...
Sliced Bread - Sliced Bread - Series 17 - Gut Microbiome Tests - BBC Sounds
Can a test tell you what's living inside your gut - and what to do about it?
bbc.co.uk
We had a fabulous time at day 1 of the first ever KIPS (Kennedy Institute Postdoc Symposium) yesterday! There were lots of great talks from postdocs across the KIR, and plenty of Powrie Lab representation! Huge thanks to the wonderful Carola Vinuesa for her keynote talk too!🥳 @kiroxford.bsky.social
Today marks the 30th anniversary of the Powrie Lab!🥳🎈 Congratulations to Fiona and everyone who has been a part of the lab through the years for the ongoing success! We’re sure that all lab members past and present are thrilled to see the lab still going strong today!🎉3️⃣0️⃣🎉 @kiroxford.bsky.social
Great opportunity for a #PhD on how lipid #metabolism regulates immune cell function in diseases such as cancer and autoimmunity. Train in immunology, bioIT, & metabolism. Apply in parallel in: 1. UNLIMITED: www.unimedizin-mainz.de/unlimited-ms... 2. Local partner site that you choose. #immunosky
The changes announced by a major UK science funder UKRI are putting scientists — and the future of research — in a difficult position, says John S. Tregoning go.nature.com/45ZO1KL
Science funding needs fixing — but not through chaotic reforms
The changes announced by a major UK science funder are putting scientists — and the future of research — in a difficult position.
go.nature.com
Thanks @weichhartlab.bsky.social and @preprintclub.bsky.social !
Amitava Sinha & @weichhartlab.bsky.social from @preprintclub.bsky.social discuss a @biorxiv-immuno.bsky.social #preprint by Heieis et al. that identifies O-GlcNAcylation as a metabolic regulator of cell cycle, enabling macrophage tissue-residency and IL-4-driven alternative activation
Another pre-print now out from the Everts' Group! For those interested in #immunometabolism #DendriticCells #Type2Immunity. Post-translational O-GlcNAcylation is a process required selectively for Th2 priming by DC. www.biorxiv.org/content/10.6...
biorxiv.org
****2-NBDG does not measure glucose uptake**** Just your regular reminder of this fact 😁. See the rigorous proof of this fact in @lindavsinclair.bsky.social 2020 paper. This paper was 6 years ago!! Stop using 2NBDG to measure glucose uptake already 🙄 pmc.ncbi.nlm.nih.gov/articles/PMC...
Single Cell Glucose Uptake Assays: A Cautionary Tale
Assays to monitor the metabolic state or nutrient uptake capacity of immune cells at a single cell level are increasingly in demand. One assay, used by many immunologists, employs 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose ...
pmc.ncbi.nlm.nih.gov
Don't miss out on your chance to attend "Fuelling the immune response IV: #UKimmunometabolismMeeting2026" Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science 📆16-17th April www.immunology.org/events/fuell...
Fuelling the immune response IV: UK immunometabolism meeting 2026 | British Society for Immunology
immunology.org
Happy to share a new preprint of one of my post doc projects. For those interested in tissue macrophages, immuno-metabolism and post-translational modification. Feedback welcome!
O-GlcNAcylation drives macrophage IL-4 responsiveness and tissue residency through metabolic and cell cycle calibration https://www.biorxiv.org/content/10.64898/2026.01.05.697622v1