New: TOP 2025 is published in RIPR. This paper updates the original 2015 framework for journals, funders, institutions, and others for promoting open research. Congrats and thanks to the TOP Advisory Board and leadership from @seangrant.bsky.social and @katiecorker.bsky.social

TOP 2025: An update to the Transparency and Openness Promotion Guidelines - Research Integrity and Peer Review

Background Transparency and openness are core scientific values that enable independent verification of reported research results. The Transparency and Openness Promotion (TOP) Guidelines, first publi...

link.springer.com

NEW #opensaccess paper "Evidence of unreliable data and poor data provenance in clinical prediction model research and clinical practice" link.springer.com/article/10.1... #researchintegrity #dataprovenance #predictionmodels #predictiveAI

🚨 Protocol -> preregistration -> preprint -> publication 🚨 125 clinical prediction model articles developed on unreliable data on stroke and diabetes. Since preprinting our results 7 articles have been retracted. doi.org/10.1186/s129...

What influences whether researchers adhere to healthcare reporting guidelines successfully? A thematic synthesis Read more here link.springer.com/article/10.1... #transparency #reportingguidelines

What a fantastic synthesis that looks into why researchers use/adhere to #ReportingGuidelines (And I'm not just saying that because my PhD work was cited in it and evaluated as 💫valuable💫 on the CASP checklist😜) link.springer.com/article/10.1...

What influences whether researchers adhere to healthcare reporting guidelines successfully? A thematic synthesis - Research Integrity and Peer Review

Background Despite endorsement by medical journals, reporting guidelines have only modestly affected reporting quality in healthcare research. We aimed to identify influences affecting whether authors...

link.springer.com

This paper is worth it for table 1 alone. 👏 @sabinehoffmann11.bsky.social @boulesteixlaure.bsky.social et al onlinelibrary.wiley.com/doi/10.1002/...

When to Adjust for Multiple Testing: A Unifying Guiding Principle

Most original articles published in the medical literature report the results of multiple statistical tests. In a few simple cases, there is agreement on whether to adjust for the number of performed...

onlinelibrary.wiley.com

NEW #openaccess PAPER in Lancet Digital Health “Critical appraisal of fairness metrics for artificial intelligence-based clinical prediction models” www.thelancet.com/journals/lan... #predictiveAI #digitaltech #AI #machinelearning #datascience #fairness #healthequity

*** NEW PAPER *** The CRT-Estimands Framework - a consensus based extension of the ICH E9(R1) addendum for cluster randomised trials - now been published in the @bmj.com. -> www.bmj.com/content/393/... + commentary in @jama.com -> jamanetwork.com/journals/jam... @unibirmingham.bsky.social

💬 Viewpoint: The #CRT-Estimands Framework defines five key attributes for cluster randomized trials, clarifying treatment effect and supporting accurate result interpretation for clinical stakeholders. ja.ma/4wG0Vcx

In a new preprint, the authors identify 124 peer-reviewed papers which used provenance-unknown Kaggle data to train AI for stroke and diabetes risk. Some sets show impossible patterns, yet models of the models are already hitting clinics. #MedSky #MedAI

Dozens of AI disease-prediction models were trained on dubious data

The models are designed to predict someone’s risk of diabetes or stroke. A few might already have been used on patients.

nature.com

New BMJ Editorial out today from @rocher.lc and me: www.bmj.com/content/393/... - Biobank's response to the news that researchers have accidentally uploaded data to GitHub multiple times is insufficient & risks trust in the UK's health data ecosystem. Everyone needs to feel responsible for privacy.

Why we won’t be funding open access publishing any more - Cancer Research UK - Cancer News https://news.cancerresearchuk.org/2026/04/01/why-we-wont-be-funding-open-access-publishing-any-more/

Why we won’t be funding open access publishing any more - Cancer Research UK - Cancer News

The open access movement was bold and promising, but ultimately disappointing. Now is the time to stop and call for a new way to make publishing work…

news.cancerresearchuk.org

Cancer Research UK withdraws funding for open access charges #OpenAccess #UK #WCRI2026 #WCRI www.researchprofessionalnews.com/rr-news-uk-o...

Cancer Research UK withdraws funding for open access charges - Research Professional News

Exclusive: Charitable funder cites “inefficient and costly” system, promising transition for researchers

researchprofessionalnews.com

*NOW OPEN FOR BOOKING* - our 4-day online training course: "Statistical Methods for Risk Prediction & Prognostic Models" Provides statistical foundations for developing, validating & updating clinical prediction models Details: www.prognosisresearch.com/training-cou... Book: tinyurl.com/mw7jtjw3

Training courses | Prognosis Research

prognosisresearch.com

Limited consensus in expert opinions on studies evaluating the design, conduct, analysis, or reporting of health research: a survey study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Comment: Research funding cuts threaten a whole generation of scientists UK will suffer lasting consequences from disrupted talent pipeline, say Mike Lockwood and James Wild, president and president-elect of @royalastrosoc.bsky.social www.researchprofessionalnews.com/rr-news-uk-v...

Research funding cuts threaten a whole generation of scientists - Research Professional News

UK will suffer lasting consequences from disrupted talent pipeline, say Mike Lockwood and James Wild

researchprofessionalnews.com

✨ New open-access book✨ I’ve seen how powerful prediction models can be, but also how often they fall short. We wrote a book, covering not just development, but also when models are needed, and how to ensure real-world impact. www.maastrichtuniversitypress.nl/cpm

%%title%% %%sep%% Maastricht University Press

Open Access book by Luc Smits, Sander van Kuijk, and Laure Wynants: This open-access textbook offers a practical and comprehensive guide to developing, validating, and implementing clinical prediction...

maastrichtuniversitypress.nl

NEW PREPRINT: “A critical review of clinical prediction models in oncology: is this SEERious research?” --> doi.org/10.31222/osf... #ClinicalPredictionModels #ResearchIntegrity #ResearchWaste #metascience #metaresearch

Hi @medrxivpreprint.bsky.social. Two (meta-research type) preprints rejected today for being out of scope for not having a meta-analysis, yet you regularly accept and preprint these types of studies (without meta-analyses), any clues for inconsistent screening today?

Redundancies at research-intensive universities double in two years. www.researchprofessionalnews.com/rr-news-uk-u...

Job losses at research-intensive universities double in two years - Research Professional News

Exclusive: Scale of redundancies revealed by RPN branded a “disaster” for UK research capacity

researchprofessionalnews.com

when your dataset is definitely real

Adrian Barnett@aidybarnett.bsky.social · 6mo ago

Much of my work in meta-research is on finding problems in research, so I've seen a lot of bad practices. However, even I was shocked by hundreds of researchers publishing papers using data that is faked and has no data provenance. www.medrxiv.org/content/10.6.... Amazing work by my student Alex.

Much of my work in meta-research is on finding problems in research, so I've seen a lot of bad practices. However, even I was shocked by hundreds of researchers publishing papers using data that is faked and has no data provenance. www.medrxiv.org/content/10.6.... Amazing work by my student Alex.

Evidence of Unreliable Data and Poor Data Provenance in Clinical Prediction Model Research and Clinical Practice

Clinical prediction models are often created using large routinely collected datasets. It is essential that prediction models are developed with appropriate data and methods and transparently reported...

medrxiv.org

Job losses at UK research-intensive universities double in two years. Exclusive: Scale of redundancies branded a “disaster”. www.researchprofessionalnews.com/rr-news-uk-u...

Job losses at research-intensive universities double in two years - Research Professional News

Exclusive: Scale of redundancies revealed branded a “disaster” for UK research capacity

researchprofessionalnews.com

We are setting out to develop some new recommendations (TRIPOD-CODE) to provide guidance on reporting the availability and structure of code for predictive AI healthcare tools Watch this space, and read the protocol here link.springer.com/article/10.1... #transparency #code #reproducibility

NEW #openaccess paper in @bmj.com led by the brilliant @matthewluney.bsky.social "Effectiveness of drug interventions to prevent delirium after surgery for older adults: systematic review and network meta-analysis of RCTs" --> www.bmj.com/content/392/... #NIHR #surgery #delirium

NEW #openaccess PAPER in BMJ Digital Health & AI "Public perceptions of health data sharing for artificial intelligence research: a qualitative focus group study in the UK" --> bmjdigitalhealth.bmj.com/content/2/1/... #digitalhealth #AI #publicperceptions #datasharing

Two openings for PhD candidates: 1️⃣ Use causal inference methods for early evaluation of the downstream effect of algorithms on patient outcomes. 👉 www.lumc.nl/en/about-lum... 2️⃣ Develop methods for evaluating patient predictions under different treatment options. 👉 www.lumc.nl/en/about-lum...

Interested in learning about IPD meta-analysis projects? Join me for a gentle introduction to the topic, in the seminar below (Wednesday Jan 28th 12 to 1pm GMT) www.ticketsource.co.uk/arcyorkshire...

Adherence to TRIPOD+AI guideline: An updated reporting assessment tool - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Delighted to share our new Perspective, published in the inaugural issue of @natureportfolio.nature.com 𝗡𝗮𝘁𝘂𝗿𝗲 𝗛𝗲𝗮𝗹𝘁𝗵. We shared opportunities and challenges of using large language models (LLMs) in global health. www.nature.com/articles/s44... #AI #LLM #Global #Health #DukeNUS