IUPHAR/BPS Guide to Pharmacology

@gtopdb.bsky.social

An open-access expert-curated resource of ligand-activity-target relationships, the majority of which come from high-quality pharmacological and medicinal chemistry literature.

Guide to Pharmacology will soon require users to register in order to use our website and use API Keys to access our REST API . These changes are expected to be made towards the end of August 2026. For more information, please see our blog post: blog.guidetopharmacology.org/2026/07/29/u...

User registration is coming to GtoPdb

The IUPHAR/BPS Guide to Pharmacology is making some changes to how the database and REST API (Web Services) are accessed. We will soon be requiring users to register with the Guide to Pharmacology …

blog.guidetopharmacology.org

‪The latest Concise Guide to Pharmacology (CGTP) has now been published bpspubs.onlinelibrary.wiley.com/toc/14765381... The 2025/26 edition provides overviews of the pharmacology of drug target families, key properties of ~1,900 human drug targets, and ~7,000 interactions, involving ~4,400 ligands

BPS Publications

The <em>British Journal of Pharmacology</em> (BJP), an official journal of the British Pharmacological Society, is the leading international general pharmacology journal.

bpspubs.onlinelibrary.wiley.com

We are pleased to announce a new IUPHAR / BPS Guide to Pharmacology database release (2025.4) - see our blog post: blog.guidetopharmacology.org/2025/12/10/d.... 91 new ligands and 106 new curated interactions. Updates also to our WHO essential medicine ligands and our chemical sub-structure search.

Database Release 2025.4

Version 2025.4 of the IUPHAR/BPS Guide to Pharmacology database was released on 10th December 2025, our fourth and final release of the year. This blog post gives details of the key content updates…

blog.guidetopharmacology.org

The IUPHAR/BPS Guide to Pharmacology is introducing commercial access fees. We want to keep GtoPdb open-access for all, but current funding landscapes means the future maintenance, curation and sustainability of GtoPdb is at risk. See our blog shorturl.at/sI0LH. @britpharmsoc.bsky.social

Commercial Access Fees for GtoPdb

Why is IUPHAR/BPS Guide to Pharmacology asking for access fees? The IUPHAR/BPS Guide to Pharmacology (GtoPdb) has always been an open-access, freely available resource. Our expert-curated database …

blog.guidetopharmacology.org