Mohamed-Ali HAKIMI
@hakimi.bsky.social
🇩🇿 🇫🇷 scientist @Inserm - https://iab-grenoble.fr/ 👀 Host-Parasite Coevolution: The Toxoplasma Paradigm ParaFrap deputy director - https://www.labex-parafrap.fr/en/ EMBO member - https://www.embo.org/ 🌍 pan-African idealist #epigenetics #parasites
🥳 Congratulations on your first paper and on such a promising trajectory! Congrats to all the collaborators and team members. a special bravo to your outstanding mentor @cristelcarles.bsky.social
Vangeli Geshkovski@vgeshkovski.bsky.social · yesterdayHappy to finally see this out in a peer-reviewed form 🧬🌱 Congrats to everyone who contributed! www.nature.com/articles/s41...
Generative AI can make it quicker and easier to write scientific research papers. But as Lucas Bietti & Adrian Bangerter argue in this Perspective, unchecked #AI use risks decoupling #writing from #thinking, undermining the foundation of scientific knowledge. 🧪 #AcademicSky doi.org/10.1371/jour...
📢 Save the date! Join us on July 2, 2026, at IAB (#Grenoble) for: 🔬 Parasite Life Cycles Unveiled: Sex, Regulation and Host Adaptation 4 leading scientists will discuss parasite development and host–parasite interactions. 🥙 Free attendance + Lebanese lunch Register: forms.gle/a5fdoVPqgNq3...
few days in Turino felt like walking through an open-air museum. between royal palaces, hidden courtyards and incredible archaeological pieces, every street had its own story to tell (great italian food too 😋). this town has this rare atmosphere: elegant, historic and alive at the same time. ☺️
New Preprint alert! Excited to share our latest work on the #MAPKinases from stellar PhD student Jill von Velsen. First structures of the MAP2K MEK1 activating its substrate MAPK between 2.9 and 3.6A - amazing resolutions for such a small and mobile complex! www.biorxiv.org/content/10.6...
A huge thank you to @inserm.fr 😄 for the visit, for the interest in our vibrant #Grenoble ecosystem, and for shining a light on our research in this short film 🎬 www.youtube.com/watch?v=dkej...
Toxoplasmose : la découverte de Mohamed-Ali Hakimi qui change la prévention entre chats et humains
YouTube video by Inserm
youtube.com
👏👏👏 Bravo @hakimi.bsky.social on winning the 2025 @inserm.fr Research Prize and the @fondationdefrance.bsky.social Allianz Prize! Hakimi's team is cracking #Toxoplasma's secrets, and developing innovative therapies to block transmission. @academiesciences.bsky.social ©Inserm/François Guénet
Huge congratulations to @hakimi.bsky.social for receiving the 2025 INSERM Research Award! 🎉 We’re extremely proud to have him as part of LabEx ParaFrap. 👉 : presse.inserm.fr/prix-inserm-...
Prix Inserm 2025 : l’innovation au cœur de la santé - Salle de presse de l'Inserm
Jeudi 27 novembre, l’Inserm célèbrera par la remise de ses prix annuels celles et ceux qui font avancer la recherche en santé. Les travaux des cinq scientifiques récompensés lors de cette édition 2025...
presse.inserm.fr
What an exceptional week! At the Collège de France, surrounded by my family 🥰 and part of my Dream Team, I was honored with the 2025 Inserm Research Prize! Truly proud. 🙏 INSERM This award goes to an outstanding team and to my loved ones who have carried me through this scientific journey.
What a day at the Académie des Sciences! 🎉 Honored to receive the Allianz Prize / Institut de France. Huge shoutout to my dream team — none of this happens without you. 🙏🏽💥 @ugrenoblealpes.bsky.social @inserm.fr @cnrs.fr
James Watson’s passing marks the loss of a major figure whose work profoundly shaped modern biology. He is also a man whose racist and misogynistic remarks can’t be separated from his legacy. Science isn’t just about discovery; it’s about upholding universal human dignity. Rest in peace.
The Guardian@theguardian.com · 9mo agoJames D Watson, co-discoverer of DNA’s twisted-ladder structure, dies aged 97
Nature Com. now live! 🎉 Silvia’s amazing PhD supervised by Alex “the Greatest” & Christopher’s big-bang contribution. Huge thanks to our stellar team & collaborators. We went fishing in the FDA pond and hooked LY2090314 🎣 Blocks GSK3 🎯in #Toxoplasma & #Crypto www.nature.com/articles/s41...
Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii - Nature Communications
Researchers identify the cancer drug LY2090314 as a potent inhibitor of Toxoplasma gondii and Cryptosporidium and report the first crystal structure of the parasite kinase TgGSK3 bound to it, validati...
nature.com
A fantastic week in Grenoble hosting my friend Amit Sharma for our @inserm.fr IRP project. With Christopher Swale on board, they pulled off a cryo-EM structure in just a few days! A great reminder that science thrives on teamwork — and friendship. Grateful to @inserm.fr for the support!
Christopher Swale just nailed his HDR — the top academic milestone in France 🎓He can now supervise PhD students on his own. Stellar talk, razor-sharp answers, the jury was impressed. Proud of you, Chris. 👏
Winter’s first snow over Grenoble, straight from the office view.
On Friday, I had the privilege of speaking with a remarkable line-up of Artur Scherf alumni at a symposium devoted to his stellar contributions to parasitology in general and malaria specifically. It was wonderful to pay tribute to a friend and visionary whose legacy continues to inspire.
So proud of my PhD student Martina Shahinas 🌟 She gave a stellar talk and shared her latest results—still chasing the sexual stages of Toxoplasma. embo.org Conference / parafrap.bsky.social was a success with an amazing speaker lineup on the ☀️Île des Embiez, Côte d’Azur.
Oh how fantastic evolution is… every day it drops a new plot twist. 🤯🧬 Nature, who coded you?! 🤩 t.co/yXmctCX6PA
Congrats Dr. Silvia DIAZ MARTIN on a brilliant PhD defense. 🙏to jury Maryse, Thierry, Matthew, Ludovic & Diego for their sharp eval. Shout-out to Alexandre and Christopher for their steady mentorship. You made us proud Silvia and I saw the whole galaxy of family pride reflected in your dad’s eyes.
🙏 @inserm.fr de promouvoir nos travaux récemment publiés dans EMBO Mol. Med doi.org/10.1038/s443... www.inserm.fr/actualite/to...
Toxoplasmose : un tandem de biomarqueurs pour diagnostiquer les infections chroniques · Inserm, La science pour la santé
Une équipe Inserm a identifié deux protéines du parasite responsable de la toxoplasmose dont le dosage combiné aiderait à identifier les infections chroniques dormantes. Ce test pourrait apporter des ...
inserm.fr
Zeus had his Hydra ⚔️, now Toxoplasma has its own. Meet Hydra: not a monster, but a brand-new protein domain. It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma. Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉 www.biorxiv.org/content/10.1...
Thrilled to share our latest review! 🎉 It captures the ideas and discussions that have shaped our work in recent years. Big shoutout to the amazing authors 👏 @hakimi.bsky.social www.sciencedirect.com/science/arti...
Decoding the epigenetic blueprint behind Toxoplasma (pre)sexual commitment and chronic persistence
Toxoplasma gondii, a widespread apicomplexan parasite, navigates a complex life cycle in which it switches back and forth between tachyzoites and brad…
sciencedirect.com
Toxoplasma facing career options: 🏃 Tachyzoite (fast life) 😴 Bradyzoite (chronic sleeper) 🙀 Pre-sexual (cat-ready) Spoiler: epigenetics makes the call. Our recent review in Current Opinion in Microbiology decodes how chromatin remodelers, TFs& AP2s orchestrate these fates 👇🏽 doi.org/10.1016/j.mi...
Redirecting
doi.org
Our July issue is online 👉 www.embopress.org/toc/17574684... The cover highlights the article by M Robert, C Swale, MP Brenier-Pinchart, @hakimi.bsky.social & al. that identifies BSM & BCLA as #biomarkers for chronic #ToxoplasmaGondii infection Scientific image by @hakimi.bsky.social @inserm.fr
EMBO Molecular Medicine: Vol 17, No 7
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
embopress.org
Thrilled to see our work featured on the cover of @embomolmed.org 🎉We identify new biomarkers to track chronic toxoplasmosis—paving the way for improved diagnosis and patient care. doi.org/10.1038/s443... It’s time to bring such tools to the clinic—let’s encourage biotech to take it from here.
Huge congrats @belenpachano.bsky.social on your PhD! Honored to have shared the journey. Your brilliance shines through your articles — past and future. You’ll be missed, but my lab will always be your home. Come back anytime. You’ve earned every success!
I hear you, brother. Loud and clear. Your courage speaks volumes. Standing strong with you—and with Palestine. You're not alone.
Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦@dudinlab.bsky.social · last yr.90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO
