A key finding of our last study is that soluble and immobilized CCL21 gradients cooperate to fine-tune different steps of lymphatic migration, revealing a new layer in leukocyte guidance. This work was only possible thanks to an amazing team effort!

Journal of Cell Biology@jcb.org · 6mo ago

uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells. New study from Victor Collado-Diaz, Maria-Nefeli Christakopoulou, Philipp Schineis, Cornelia Halin @halinlab.bsky.social @ethz.ch and colleagues: rupress.org/jcb/article/... #Immunology #Migration #motility

We are looking for an enthusiastic and talented postdoc to join our team and advance 3D imaging and organ-on-chip models, by studying leukocyte migration in human lung lymphatics in an interdisciplinary @snsf.ch -funded project at @ethz.ch If you are interested, check here: lnkd.in/dw9gzFjW

Check out our new study in @jem.org on #Lymphatics using #SingleCell and #3DImaging in human skin, revealing new features of the lymphatic vascular system in #HumanBiology!

Journal of Experimental Medicine@jem.org · 9mo ago

Transcriptomics- and 3D imaging-based characterization of the lymphatic vasculature in human skin. New study from Aline Bauer, Cornelia Halin and colleagues @ethz.ch: rupress.org/jem/article/... #CardiovascularBiology #InnateImmunity #inflammation #Lymphatics

We are so excited to announce that our latest paper is out in @jem.org By combining single-cell RNA sequencing and 3D imaging, we reveal striking structural and molecular differences between human and mouse dermal lymphatic vasculature, opening up new perspectives on #Lymphatics and #HumanBiology