Harald Ringbauer
@hringbauer.bsky.social
Population Geneticist | Ancient DNA Research Group Leader at MPI-EVA Leipzig www.hringbauer.com
Reminder Postdoc job looking at aDNA of dogs at the NHM @nhm-london.bsky.social Deadline tomorrow 16th June jobs.nhm.ac.uk/Job/JobDetai...
Postdoctoral Researcher ancient DNA:South Kensington
jobs.nhm.ac.uk
Great to see @annikafreudiger.bsky.social paper published! 🎉 We analyzed how genetic markers are used to estimate relatedness in wild animals - a big field with 2861 relevant publications. 📈🧬 Even in 2026 mainly STRs are used - and we argue for low coverage WGS data and a simple aDNA estimator.
Molecular Ecology@molecology.bsky.social · 2mo agoNew in MEC! @annikafreudiger.bsky.social et al. assess genetic relatedness on rhesus macaques and find that low-coverage whole-genome sequencing offers an accurate, cost-effective alternative to widely used methods. @wileyecology.bsky.social 📷 Caribbean Primate Research Center 🔗 buff.ly/pPOONsu 1/3
It is great to now have a proper way to cite pileupCaller! The code to generate pseudohaploid genotypes from BAMs is one of the most quoted github code chunks in human ancient DNA research.
Stephan Schiffels@stschiff.bsky.social · 3mo agoFinally an official publication of Pileupcaller. Please cite. Thanks to @joss-openjournals.bsky.social for the review process and publishing!
Finally an official publication of Pileupcaller. Please cite. Thanks to @joss-openjournals.bsky.social for the review process and publishing!
Journal of Open Source Software@joss-openjournals.bsky.social · 3mo agoJust published in JOSS: 'PileupCaller: A command-line tool to sample genotypes from low-coverage sequencing data of ancient DNA' https://doi.org/10.21105/joss.08634
🚨 Check out our new paper in Nature! In our new study, we sequenced 128 high-coverage genomes from Indigenous peoples across Latin America and uncovered their unique genetic diversity and history. 👇🧵 www.nature.com/articles/s41...
The evolutionary history and unique genetic diversity of Indigenous Americans - Nature
Analysis of 128 high-coverage Indigenous American genomes shows extensive diversity shaped by several South American dispersals, ancient Australasian admixture, archaic introgression and long-term ada...
nature.com
New paper alert 🚨 Researchers at #CPGStlhm have analyzed ancient genomes from an Islamic cemetery in Ibiza (950–1150 CE) 🏖️ They found a highly diverse community with ancestry from Europe and North Africa! The paper was published in @natcomms.nature.com OA link www.nature.com/articles/s41...
Out today is our paper 'Genomic history of early dogs in Europe', in which we uncover the identity of the dogs that lived in Europe before agriculture—during the Paleolithic & Mesolithic periods: doi.org/10.1038/s415.... A thread ⬇️ (10) @biouea.bsky.social @crick.ac.uk @mpi-eva-leipzig.bsky.social
We just published a brief preprint on aDNA from two Medieval Ottonic emperors. 🧬👑 We confirm via IBD segments that remains attributed to Otto "the Great" and "Saint" Heinrich are third-degree relatives. As historically attested - suggesting that they are authentic. ✅️ doi.org/10.64898/202... (1/3)
The HAAM summer school is always a fantastic online workshop on popgen analysis via aDNA. Check out the 2026 version! ⬇️💡🧬
HAAM-community@haam-community.bsky.social · 5mo ago🆕 HAAM Summer School 2026 📅 June 1-5, 2026 📍 Online 💰 Free 🧑🔬🧑💻 For Students & ECR 🔓 Applications open until April 13, 2026! 🔗 Apply here: forms.gle/ckqTgQxnEENJ...
🆕 HAAM Summer School 2026 📅 June 1-5, 2026 📍 Online 💰 Free 🧑🔬🧑💻 For Students & ECR 🔓 Applications open until April 13, 2026! 🔗 Apply here: forms.gle/ckqTgQxnEENJ...
What happens when violence targets the future of a society? Our new paper in Nature Human Behaviour examines one of Europe’s largest prehistoric mass graves and finds evidence for selective violence directed against women and children in the Early Iron Age. www.nature.com/articles/s41...
A large mass grave from the Early Iron Age indicates selective violence towards women and children in the Carpathian Basin - Nature Human Behaviour
In this analysis of biomolecular and archaeological data from a ninth-century BCE mass grave in the Carpathian Basin, Fibiger et al. find evidence for the targeted killing of mostly unrelated women an...
nature.com
Really excited to share our new paper on the Early Iron Age mass grave at Gomolava (9th c. BCE), a study I had the pleasure to work on during my PhD with an amazing group of co-authors across multiple disciplines. Open access link: www.nature.com/articles/s41... 🧵👇
A large mass grave from the Early Iron Age indicates selective violence towards women and children in the Carpathian Basin - Nature Human Behaviour
In this analysis of biomolecular and archaeological data from a ninth-century BCE mass grave in the Carpathian Basin, Fibiger et al. find evidence for the targeted killing of mostly unrelated women an...
nature.com
Excited and proud 😊 to share the final chapter of @hjorvik.bsky.social 's PhD thesis: Seven Millennia of Human Exploitation drove genomic Changes in Iberian Sheep Comments welcome! 🧬🧪🏺🐑 www.biorxiv.org/content/10.6... 🧵(1/8)
biorxiv.org
Interested in using aDNA time-series datasets to estimate selection? Our study "Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data" is now out in GBE! doi.org/10.1093/gbe/... @genomebiolevol.bsky.social @cegamorim.bsky.social
Assessing Ancient DNA Sampling Strategies for Natural Selection Inference in Humans Using Allele Frequency Time Series Data
Abstract. The increased availability of genomic data from ancient humans allows estimating the strength of natural selection at a given locus using time se
doi.org
We hope this little guide and review of the recent literature on SVs will be useful for the community in #ecology #evolution #genomics #PopGen. Great lead by Kat!!
Katarina Stuart@katarinastuart.bsky.social · 6mo agoNew review! Theory & a practical guide to structural variants in popgen🧬 Many thanks to my co-authors: @rebekahoomen.bsky.social @annatigano.bsky.social @marenwellenreuther.bsky.social @janawold.bsky.social @dlfield.bsky.social @clairemerot.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
(1/2) The preprint of our perspective on genetic estimates of relatedness in animal populations is out! Big Congratulations to Annika! doi.org/10.32942/X28... A systematic review of 2,861 articles shows that, even in 2025, 75% of such studies use microsatellites. And most use only a few! #PopGen
We developed/optimised the protocol to enrich low aDNA content libraries using Twist panels. 🎣🧬👩🔬 #aDNA #Labwork
bioRxivpreprint@biorxivpreprint.bsky.social · 7mo agoLets Tweap again: Economic and SNP retrieval optimisation for target enrichment of ancient DNA https://www.biorxiv.org/content/10.64898/2026.01.15.699081v1
SciLifeLab has opened a call for #postdoc fellows in Data-Driven Life Science. We would be happy to host such fellows! Get in touch if you are interested in applying with a project on the evolution of humans and domestic animals using ancient and/or modern DNA 🧪🏺 www.scilifelab.se/data-driven/...
DDLS Research School Postdoc call 2026
Call for Academic and Industrial Postdoctoral Fellowships in Data-Driven Life Science 2026 Generic Description of the DDLS Postdoc Program The SciLifeLab and Wallenberg National Program for Data-Drive...
scilifelab.se
#AI may indeed exacerbate our bad academic habits: #LLM science summaries were nearly five times more likely than human-authored science summaries to contain broad generalizations (95% CI [3.06, 7.70], p < 0.001). And newer models over-generalized more; not less! doi.org/10.1098/rsos... #philSci
Generalization bias in large language model summarization of scientific research
Abstract. Artificial intelligence chatbots driven by large language models (LLMs) have the potential to increase public science literacy and support scient
doi.org
Matt Grossmann@mattgrossmann.bsky.social · 7mo agoBecause AI models are trained on current research practices, they may exacerbate our tendencies like overselling results from limited data, overinterpreting statistical significance, & quickly claiming causality, especially because they are even better at generating interpretations of any results
This smells distinctly like collider bias and/or selection bias and/or regression to the mean... You simply can't select teen prodigies, and world class athletes rom databases, and go run regressions without serious consideration of the selection process!
Mike Inouye@mikeinouye.bsky.social · 8mo ago"Most top achievers (Nobel laureates and world-class musicians, athletes, chess players) demonstrated lower performance than many peers during their early years. Across the highest adult performance, peak performance is negatively correlated with early performance" www.science.org/doi/10.1126/...
Have you ever wondered: just how strong *is* the evidence for Muller's ratchet on mtDNA? Well, wonder no more! (Project led by Yu Mo, with @smishra677.bsky.social and @yadirapga.bsky.social) "No molecular evidence for Muller's ratchet in mitochondrial genomes" www.biorxiv.org/content/10.6...
No molecular evidence for Muller's ratchet in mitochondrial genomes
Muller's ratchet predicts that non-recombining genomes can accumulate deleterious mutations, though molecular evidence for it is rare. Previous studies have tried to detect ratchet-like behavior in mi...
biorxiv.org
Happy to share my work with my advisor Zachary Szpiech! Why are associations between ROH & complex traits inconsistent across studies? We use realistic simulations to show how demographic history and genetic architecture interact to shape the phenotypic impact of ROH. www.biorxiv.org/content/10.6...
The Influence of Demographic History and Genetic Architecture on Complex Traits via Runs of Homozygosity
Runs of homozygosity (ROH) are contiguous genomic regions where all sites are homozygous, inherited from identical haplotypes due to shared ancestry. The number and length of ROH in individuals varies...
biorxiv.org
A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV
SKULL OF THOMAS AQUINAS: TAKE A LEFT NOW PRIEST: No, the GPS says we have to keep going— SKULL: I KNOW A SHORTCUT PRIEST: Do you remember the last ti— SKULL: FOR THOSE WITH FAITH, NO EVIDENCE IS NECESSARY; FOR THOSE WITHOUT IT, NO EVIDENCE WILL SUFFICE
Sardonicus@sardonicus.eu · 8mo ago'Skull of St. Thomas Aquinas being transported to Fossanova Abbey.' Photograph by Daniel Ibanez
What's that? 5 ancient doggy papers in 10 days is too many dogs? Can I interest you in some cats? Perhaps a complete retelling of cat domestication, dispersal, and replacement across Eurasia? As you wish! Science www.science.org/doi/10.1126/... Cell Genomics www.cell.com/cell-genomic...
The dispersal of domestic cats from North Africa to Europe around 2000 years ago
The domestic cat (Felis catus) descends from the African wildcat Felis lybica lybica. Its global distribution alongside humans testifies to its successful adaptation to anthropogenic environments. Unc...
science.org
I taught (and co-taught) a course on human population genetics from 2000-2024. Having retired, I'm now making all the course materials public: github.com/alanrogers/p... #popgen #evbio
GitHub - alanrogers/popgen: A course on population genetics
A course on population genetics. Contribute to alanrogers/popgen development by creating an account on GitHub.
github.com
As I told the CNN, without details and data it is not possible to assess the claims. More importantly, the scientific value of this media campaign, balanced against the possible stigmatization of individuals with these real conditions today, is highly questionable. edition.cnn.com/2025/11/13/s...
Researchers say they have verified and sequenced Hitler’s DNA – and found a genetic disorder | CNN
Analysis of Adolf Hitler’s DNA reveals he may have had a rare genetic disorder that can delay puberty.
edition.cnn.com
Putting aside the deeper issues of why this analysis was done and how it has been promoted, the choice to broadcast a tv show before releasing a preprint should make people skeptical of the results. How can one be sure of their scientific claims?
Pontus Skoglund@pontus-skoglund.bsky.social · 9mo agoAs I told the CNN, without details and data it is not possible to assess the claims. More importantly, the scientific value of this media campaign, balanced against the possible stigmatization of individuals with these real conditions today, is highly questionable. edition.cnn.com/2025/11/13/s...