Super cool cryo-ET work from my colleague Xiaohan resolving a ton of ribosome assembly intermediates in the nuclei of human cells!

bioRxiv Cell Biology@biorxiv-cellbio.bsky.social · 2mo ago

In-cell structures visualize human pre-ribosome assembly in the nucleolus https://www.biorxiv.org/content/10.64898/2026.06.01.729245v1

Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6...

Amazing and super beautiful work @mdreimann.bsky.social! 🎉 Congrats for you and the whole team! 🎉

mdreimann.bsky.social@mdreimann.bsky.social · 2mo ago

Super excited to share my first paper from my PhD in the @dodonova-sveta.bsky.social lab. We visualise how chromatin from archaeal cells is organised using cryo-ET and SPA. Big thanks to everyone involved in this project!

Nature research paper: SNOR promotes translation restart after dormancy go.nature.com/3RnxFqG

SNOR promotes translation restart after dormancy - Nature

High-resolution in situ cryo-electron tomography in Schizosaccharomyces pombe identifies SNOR protein, which binds to ribosomes during dormancy induced by glucose depletion, priming them for rapid reactivation of protein synthesis upon glucose repletion.

go.nature.com

Thrilled to share the updated video of my paper in Nature with Maciej (under supervision of @simonemattei.bsky.social & @jomaalab.bsky.social) Proud to use Cryo-ET to uncover how hibernation factors are key to translation restart! To model PTMs in situ and render animations fulfilled my PhD dream!🥹🎉

EMBL@embl.org · 3mo ago

Despite its name, SNOR, a newly discovered protein, is hardly asleep on the job. EMBL researchers’ newest technologies allowed their scientific collaboration to discover a tiny protein with a big role in awakening cells from dormancy to restart protein synthesis. www.embl.org/news/science...

New preprint🧊🔬Introducing LowDoseWizard—a guided SerialEM workflow for rapid, standardised cryo-TEM setup! Setting up low-dose can be slow & daunting, especially for new users. LowDoseWizard automates optics, camera, and alignment steps from minimal input — full setup in <15 min. #cryoEM #SerialEM

cryoEM papers@cryoempapers.bsky.social · 3mo ago

LowDoseWizard - rapid and standardised setup of low-dose cryo-TEM imaging in SerialEM www.biorxiv.org/content/10.64898/2026.05.05.722937v1 #cryoEM

Excited to share our work uncovering SNOR, a ribosome-associated factor that promotes translation restart after dormancy published in Nature!! This was, as usual, a wonderful collaborative effort between our group and the Mattei Lab @simonemattei.bsky.social @embl.org www.nature.com/articles/s41...

Really happy to share my 1st first-author work during my PhD @embl.org co-leading with Maciek! 🥳 A serendipitous project shaped with a lot of curiosity and “coffee” (no hibernation😅) I’m really proud of the story we built together! 😊 Excited to share the final version soon with even cooler results 🤩

cryoEM papers@cryoempapers.bsky.social · 4mo ago

A Novel Eukaryotic Ribosome Factor Enables Translation Restart Following Cellular Dormancy www.biorxiv.org/content/10.64898/2026.03.21.713407v1 #cryoEM

Microscopy Nodes is now up on bioRxiv! 🚀 This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev). High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬 www.biorxiv.org/content/10.1...