Hartmut Vodermaier
@hvodermaier.bsky.social
Senior Scientific Editor for @embojournal.bsky.social @embopress.org Ubiquitin & other PTMs, cell cycle & cell division, 3R stuff (replication, recombination, repair). Opinions my own. He/his.
a plant SUMO E3 that looks like a STUbL - this was quite a surprise...
The EMBO Journal@embojournal.org · last mo.In issue 13: Review: roles of nonsense-mediated RNA decay New SUMO ligase in plant immunity Mitochondrial calcium uptake in Alzheimer’s progression Mechanosensitive FHL2 and microtubule-actomyosin crosstalk Cover: Zheng, Hu, Long et al link.springer.com/journal/4431...
The end of a great meeting: #EMBOevents #EMBOtelomere Our editor @hvodermaier.bsky.social presents the @embojournal.org poster prize to winner Valeria Rubeo from @crcm.bsky.social - congratulations! meetings.embo.org/event/26-tel...
Beautiful cover this time - makes me miss the days when they were still produced to adorn real print issues in all their glory!
The EMBO Journal@embojournal.org · 4mo agoIn ISSUE 7: Perspective: Molecular evolution of animal aging Review: eIF3 roles in cells and disease Sorting nexins & hybrid endosomal coats Purine metabolism supported by microcephaly protein WDR62 Cover: Biao Gong and colleagues link.springer.com/journal/4431...
Happy to see the first paper from the lab published in the EMBO J today: link.springer.com/article/10.1... In it, we reconstitute self-assembling cooperative oligomers of human Ndc80 and Ska kinetochore complexes that stabilise microtubule ends, and study these samples using cryoET and TIRF
Microtubule end stabilisation by cooperative oligomers of Ska and Ndc80 complexes - The EMBO Journal
During mitosis, properly aligned chromosomes stabilise microtubule ends with the help of kinetochores to ensure timely segregation of chromosomes. Microtubule-binding components of the human outer kin...
link.springer.com
Only three more days, excited to meet the ubiquitin crowd again at #KSUbiquitin26 @keystonesymposia.bsky.social hubs.la/Q03TCqzV0
See also the great News&Views comment by Monica Gobran and @plenart.bsky.social - highlighting all three papers! link.springer.com/article/10.1...
Mitotic entry: Bora takes Polo to Aurora, and gives them a hug - The EMBO Journal
The EMBO Journal - Cell division involves the complete reorganization of the cellular architecture, requiring precise coordination of cellular processes in space and time, but how does this control...
link.springer.com
Cannot help but feeling the Impact Factor hype may have gone awry by now...?
Happy Advent! !!!🎄✨ Day 2. Today's puzzle is about paper mills' red flags! Do you spot the problem? papermills.tilda.ws/advent2025
As my conference year draws to a close: still one last highlight coming up #EESNucleus on home turf @events.embl.org!
It's been an amazing year for the new PTM field of #MARUbylation - happy that I could get involved first-hand!
Jonathan Pruneda@jnpruneda.bsky.social · 9mo agoExcited to share the peer-reviewed version of our work, now online in @embojournal.org! Big thanks to our reviewers and @hvodermaier.bsky.social for facilitating this process. Looking forward to continuing this fun collaboration with @michaelnadbio.bsky.social! www.embopress.org/doi/full/10....
On the train to Montpellier for the #EMBOsumoylation conference - looking forward to the 2nd recurrence of this #EMBOevents workshop and to the latest research in the SUMO field! meetings.embo.org/event/25-sum...
SUMOylation: From discovery to translation
Sumoylation is an essential post-translational modification that regulates thousands of target proteins in a dynamic manner. Small ubiquitin-like modifiers (SUMOs) can be attached to target proteins …
meetings.embo.org
I continue to be astounded by the recent resurgence of intriguing studies revolving around #PARPs and the interplay of ADP-ribosylation with other PTMs! Latest example that we published in @embojournal.org:
The EMBO Journal@embojournal.org · 11mo agoA general rather than site- & function-specific role for protein modification by ADP-ribosylation? @kfeijszaja.bsky.social , Roko Zaja and coworkers find that labeling by #PARP7 facilitates ubiquitin-dependent degradation of multiple targets upon proteotoxic stress www.embopress.org/doi/full/10....
Was fun to work on this manuscript - never would have thought that an E1 enzyme could be involved in selecting a particular #ubiquitin -like protein isoform over another!
The EMBO Journal@embojournal.org · 11mo agoWhat is the basis & significance of SUMO1 vs SUMO2/3 conjugation preference? Jo Morris et al find that mitotic deacetylation biases SUMO E1 SAE2 towards #SUMO1 conjugation onto NuMA to ensure faithful chromosome segregation #RefereedPreprint c/o @reviewcommons.org www.embopress.org/doi/full/10....
Our RNA & translation editor Cornelius Schneider is excited to be at #EMBLProtein starting tomorrow – make sure to say Hi to him and drag him to your posters 😀 @events.embl.org
Fascinating new insights into evolutionary conservation/diversification/repurposing in the chromosome segregation machinery!
Stan Yatskevich@stanislauy.bsky.social · last yr.Happy to share our latest work on the structure and assembly of holocentric kinetochores! Huge thanks to Ines for a very fruitful collaboration, Claudio for all the support, and congratulations to Christine and all co-authors! www.biorxiv.org/content/10.1...
Another week, another great conference - happy to be at #EESAgeing on home turf
EMBL Events@events.embl.org · last yr.📣 If you still want to join #EESAgeing you can do so by signing up for virtual participation 💻 ⏰ You have until 3 June to register here: https://s.embl.org/ees25-05-bl Don't miss this international event that will focus on the molecular mechanisms of ageing and age-related diseases 🧬⏳
Senate Democrats warn Trump plan to wipe out public broadcasting funding will shut down stations, eliminate essential services. But House GOP scheduled to vote to clawback $1.1 billion next week.
Partisan battle lines form over Trump's plan to defund NPR & PBS
Senate Democrats warn Trump plan to wipe out public broadcasting funding will shut down stations, eliminate essential services. But House GOP scheduled to vote to clawback $1.1 billion next week.
n.pr
This vital resource @flybase.bsky.social is in acute peril: its funding blocked by the vindictiveness of Trump. Emergency funds needed *now*, pending longer term solutions. Personal donations from Europe can be made here (UK taxpayers can gift-aid); other routes also possible. US appeal to follow.
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
philanthropy.cam.ac.uk
A scary situation!
Lucas Waltzer @lucaswaltzer.bsky.social · last yr.#drosophila @flybase.bsky.social request emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate! www.philanthropy.cam.ac.uk/give-to-camb...
‘Anyone can do this’: Sleuths publish a toolkit for post-publication review @averyorrall.bsky.social reports on an initiative from @reeserichardson.bsky.social and colleagues
‘Anyone can do this’: Sleuths publish a toolkit for post-publication review
For years, sleuths – whose names our readers are likely familiar with – have been diligently flagging issues with the scientific literature. More than a dozen of these specialists have teamed up to cr...
retractionwatch.com
If you are interested in pursuing a postdoc combining proteomics a genomics with functional molecular biology to study ubiquitin (-like) signaling in genome biology we are looking for candidates for the next MSCA Fellowships call!!!!
Today, these amazing NKI researchers are pushing their limits by climbing the Alpe d’Huez. Go for it lovely people! We are proud to see so many of you dedicate your time and effort to supporting cancer research. With @oncodeinstitute.bsky.social #AlpedHuZes #cancerresearch #ad6 #NKI
Grateful for the opportunity to meet with so many enthusiastic early-career scientists and sharing behind-the-scenes insights with them #wUeBI2025
GRK2243@grk2243.bsky.social · last yr.New day, new opportunities for connection! Conference participants meet with the EMBO Journal editor, Hartmut Vodermaier, for an engaging discussion on publishing, peer review, and the future of scientific communication. A valuable and inspiring exchange! #wUeBI2025
Excited that the symposium #wUeBI2025 @grk2243.bsky.social is now about to start - looking forward to exciting news from the #ubiquitin field, and to meeting this great community again!
Ever wondered how it would be as an Editor? Here's your chance to try as an absence cover with our wonderful colleagues from @emboreports.org!
EMBO Reports@emboreports.org · last yr.Want to join our team? We are looking for an editor. -> embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
Great to get to publish another one on the emerging connections between ADP-ribosylation, immune signaling, ubiquitin and protein aggregation/degradation
Anthony Leung@leunglab.bsky.social · last yr.🥳 Out now @embojournal.org! Interferon induces a new class of p62 bodies, with #antiviral & #immunotherapy implications. p62 is usually linked to #autophagy — but not here. These are driven by PARP14-mediated ADP-ribosylation & rely on #ubiquitin #proteasome system. www.embopress.org/doi/full/10....
