The first story coming out from a much larger experimental setup, co supervised with @jingli-0512.bsky.social.

Evomics Lab@evomicslab.bsky.social · 3d ago

Happy to share our recent preprint on experimental evolution for bleomycin resistance in yeast, in which we highlight both background-dependent mutational footprints and a shared molecular mechanism underlying their adaptation. www.biorxiv.org/content/10.6... #yeast #LTEE

Great collaboration with Dr. Na Liu and Dr. Jun Ma's teams! It was a fun journey to expand our research footprint into cancer-associated microorganisms. Special thanks to @simonemozzachiodi.bsky.social for critically reading our manuscript and providing valuable feedback. 🧬🦠

Evomics Lab@evomicslab.bsky.social · 3w ago

Glad to see this joint work on nasopharyngeal microbiota culturomics published in #ScienceTranslationalMedicine, featured as a cover story! By building this local bacterial catalog, we characterized a Fusobacterium-Prevotella mutualism in nasopharyngeal tumors. www.science.org/doi/10.1126/...

How good is MiniBWA, the successor to BWA? To test it, I ran MiniBWA on sequencing from 76 different species, comparing mapping speed, rate and accuracy with BWA MEM. In short, it's really good. If you map short reads, it's well worth your time. andrewcarroll.github.io/2026/06/30/t...

Came back to US for the first time after my PhD to attend the @genetics-gsa.bsky.social #Yeast26 Genetics Meeting. Great to meet many colleagues from the North American yeast community, whose research I have followed through papers. Until next time~

Great to come back to Nice, an ever charming & cozy city that I’ve spent good five years of my life ! Had a lovely reunion with my postdoc advisor @litinice.bsky.social as well as both old & new friends at @ircan.bsky.social. Until next time, à bientôt ~

Proud to have played a part in this multi-lab collaboration! 😀

Evomics Lab@evomicslab.bsky.social · 4mo ago

Glad to see this joint work finally out in Nature Cancer @natureportfolio.nature.com ! A truly tour-de-force multiomics quest into nasopharyngeal carcinoma subtyping and its clinical implications! www.nature.com/articles/s43...

⏰ Only 2 DAYS left for early registration! Join us at #Yeast26 (June 13-17, Pacific Grove, CA) for cutting-edge research in #genetics, #genomics, #disease, #regulation, #systemsBiology, #cellBiology, #lifeCycle, #syntheticBiology, & more. Register by April 16 to save! 🧬 genetics-gsa.org/yeast-2026/

Such a big relief to see my much belated PhD project finally wrapped up, after so many years and so much ups and downs ... "It is a long way from amphioxus, but we all came from there" ~

Evomics Lab@evomicslab.bsky.social · 5mo ago

Excited to share our PNAS paper on the genome evolution of an early-diverging #amphioxus, Asymmetron lucayanum! There is a long and twisty story behind this work, which also explains the username choice of the lab PI @iamphioxus.bsky.social . 😀 @pnas.org www.pnas.org/doi/10.1073/...

very happy to have this work published in mbe @molbioevol.bsky.social can now use phyloHessian to get a (hopefully) improved div time & subs rate estimate, particularly for deep-time or fast‑evolving lineages github.com/evolbeginner... #julialang #iqtree #mcmctree #molecularclock

GitHub - evolbeginner/phyloHessianWrapper

Contribute to evolbeginner/phyloHessianWrapper development by creating an account on GitHub.

github.com

Molecular Biology and Evolution@molbioevol.bsky.social · 5mo ago

@sishuowang.bsky.social & Meade introduce phyloHessian, using complex mixture substitution models in molecular dating. Empirical analysis of ancient symbiont lineages leads to a revised understanding of their host association origins. 🔗 doi.org/10.1093/molbev/msag039 #evobio #molbio #compbio

The abstract submission deadline for #Yeast26 has been extended to next week, March 12! 📣 GSA is committed to meeting the needs of our genetics community and supporting our scientists through challenging times. Join us at the stunning Asilomar. Submit your abstract now: buff.ly/XmP8Z2i

Abstract Submission - Yeast Genetics Meeting 2026

Visit our website to learn more.

buff.ly

David Botstein, a titan within the scientific community, died last week. GSA mourns his passing and celebrates his legacy. Read more about his significance to our community in this thread ⬇️🧵

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD. www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

ANNOUNCEMENT: The webpage for the upcoming yeast meetings of 2026 has recently been updated. Have a look at it to find out which exciting #yeast #conferences are ahead!!! 😀 onlinelibrary.wiley.com/page/journal...

Yeast | Microbiology Journal | Wiley Online Library

Yeast is a microbiology journal for research in the rapidly moving field of yeast biology. We publish the most significant developments in unicellular fungi.

onlinelibrary.wiley.com

The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-3...

📢 It has been a few years since we updated LRSDAY last time, during which the downloading URLs of some of its dependencies have become inaccessible. I've just implemented a fix in GitHub make the automatic installation script work again. github.com/yjx1217/LRSDAY

GitHub - yjx1217/LRSDAY: LRSDAY: Long-read Sequencing Data Analysis for Yeasts

LRSDAY: Long-read Sequencing Data Analysis for Yeasts - yjx1217/LRSDAY

github.com

Jia-Xing Yue (@iamphioxus.bsky.social), principal investigator at Sun Yat-sen University, is one of the new members of the GBE editorial board. He is an expert in evolutionary genomics, genome instability, telomeres, aneuploidy, cancer, and yeast. #societyjournal

Honored to serve @genomebiolevol.bsky.social and the greater @official-smbe.bsky.social community! 🫡

Genome Biology and Evolution@genomebiolevol.bsky.social · 6mo ago

GBE proudly welcomes seven new Associate Editors to its Editorial Board! These researchers bring vast experience in genomic sciences and evolutionary biology, and will provide a great service to the SMBE community. We will be presenting these colleagues throughout the coming days. #societyjournal

Honored to serve on the Yeast Genetics Meeting Program Committee of Evolution & Population Genetics. Welcome for meeting registration and abstract submission, especially on our Evolution & Population Genetics program! genetics-gsa.org/yeast-2026/ @genetics-gsa.bsky.social #Yeast26

Homepage - Yeast Genetics Meeting 2026

Visit our website to learn more.

genetics-gsa.org

SMBE is now on Weixin/WeChat! Stay up-to-date with the latest news, events, and articles published in @molbioevol.bsky.social and @genomebiolevol.bsky.social Follow the @officialSMBE account, or scan the QR code with the app. 🔗 academic.oup.com/smbejournals/pages/wechat #society

It is great to have @petrovadmitri.bsky.social here at Sun Yat-sen University Cancer Center to give us an highly inspiring talk on “Fitness landscape of tumor suppressor genes in lung cancer ”. Tour de force experiments, mind blowing results, and exciting bench-to-bed perspectives!

First #SMBE meeting for our lab！Definitely a memorable experience. Already looking forward to the next one! @official-smbe.bsky.social #SMBE2025

Two papers in today's issue of @nature.com ‬: 1) we assemble 65 genomes to near completion, including centromeres and the MHC. tinyurl.com/3huhax6w. 2) we sequence 1,019 genomes from the 1kGP with long reads, revealing SVs down to low allele frequencies tinyurl.com/wbx3we9x.

Complex genetic variation in nearly complete human genomes - Nature

Using sequencing and haplotype-resolved assembly of 65 diverse human genomes, complex regions including the major histocompatibility complex and centromeres are analysed.

tinyurl.com

Super honored to have chance to co-organize the #SMBE2025 Symposium on Experimental Evolution, together with @jingli-0512.bsky.social and Dao-Qiong Zheng. Thank @petrovadmitri.bsky.social for serving as our invited speaker. Also thank all the oral/poster presenters and audience. @OfficialSMBE

📣Our #SMBE 2025 Symposium (No. 3) on Experimental Evolution will be held today (7.22, Tuesday) at 10:30 in Room 4, Building No. 8. An associated poster session will be held at 14:00 (poster number: S3-P01~P16). Welcome to join! let's study evolution in action! 🥳 🎉 @official-smbe.bsky.social

📅 The day is today! #SMBE2025 in Beijing starts now, as the registration desk opens to all participants. Join us for five days full of the latest discoveries in molecular biology and evolution 🧬 We hope all attendees enjoy the many opportunities for discussion and networking among our community.

Our latest paper is out: rdcu.be/ev6Ym — one of my favorite projects. It began about 8 years ago when Nobel laureate Torsten Wiesel asked me: what transcription factors regulate new genes? I had no idea then. Now we have some answers.

Gene regulatory networks and essential transcription factors for de novo-originated genes

Nature Ecology & Evolution - A combination of computational methods applied to single-cell RNA sequencing data and genetic experiments shows that a small number of transcription factors are...

rdcu.be

Welcome to attend our SMBE2025 Symposium on Experimental Evolution. Co-organized by Dao-Qiong Zheng, @‪jingli-0512.bsky.social‬ and myself.

Society for Molecular Biology and Evolution@official-smbe.bsky.social · last yr.

#SMBE2025 Symposium 3: Experimental evolution: studying evolution in action 🔗 smbe2025.scimeeting.cn/en/web/program/25070

Very excited about this work by @mrazo.bsky.social in collaboration with www.madhavmani.com bsky.app/profile/mraz... I am so lucky to be able to collaborate with such brilliant people! Learned a lot. This is our first foray into ML approaches and I am quite taken with their power 1/n

1/n 🧵 Excited to share our new paper! We developed a framework to reveal hidden simplicity in how organisms adapt to different environments, particularly focusing on antibiotic resistance evolution. #EvolutionaryBiology #MachineLearning

Keynote talk from Steven McCarroll from last weeks Biology of Genomes conf. My favorite talk of the whole meeting! #bog25 youtu.be/BCRAlmFv7ag?...

CSHL Keynote, Dr. Steven McCarroll, Harvard Medical School + Broad Institute

YouTube video by CSHL Leading Strand

youtu.be

📢 3 Postdoc positions available in @evomicslab.bsky.social targeting on genome instability evolution of both yeast and human genomes. Both computational genomics and experimental genomics backgrounds are welcome! 🧬🧑‍💻🧪 For more information, see evomicslab.org or send me a message!