Believe it or not, the term Translon as the translational unit predates Walter Gilberts 'Exon' (1978). In 1973 Suresh Goel had a letter published in Nature arguing for the establishment of units of Transcription (Transcon) and Translation (Translon). www.nature.com/articles/245...

Aaron and the Hoskins Lab at UW Madison@uwmadisonrna.bsky.social · 11mo ago

I think my favorite part is that it rhymes with "exon"

Here's an interesting paper @natmethods.nature.com introducing the term "Translon", filling a terminology gap in the field of gene expression. Kudos to Pasha Baranov for leading this initiative and gathering many contributors (including myself) for an healthy discussion on fundamental principles 👏

Jack Tierney@jackatierney.bsky.social · 11mo ago

Many transcriptome regions are translated but not known to encode proteins. They remain poorly annotated and thus under studied, partly due to the lack of terminology for these features. In @natmethods.nature.com we propose using "Translon" for any region decoded by the ribosome

Many transcriptome regions are translated but not known to encode proteins. They remain poorly annotated and thus under studied, partly due to the lack of terminology for these features. In @natmethods.nature.com we propose using "Translon" for any region decoded by the ribosome