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Mariotti Genomics Lab

@mariottilab.bsky.social

Comparative genomics of gene expression lab at Universitat de Barcelona @geneticsub.bsky.social, led by Marco Mariotti. Interests: Translational recoding, bioinformatics, evolution, biotech, rare diseases. https://www.mariottigenomicslab.com/

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Mariotti Genomics Lab@mariottilab.bsky.social · last mo.

Looking forward to Martina Yordanova's talk in our department! If you're around, don't miss it!

Genetics UB@geneticsub.bsky.social · last mo.

🗣Xerrada de la Prof. Martina Yordanova (Lecturer at the School of Biochemistry & Cell Biology,Univ.College Cork) 🧬"One mRNA,Many Proteins:Translational Control of Protein Isoforms" 📍Aula M1 @biologiaub.bsky.social 🗓️16 Juliol 🕛12.00 h Organitzada per @mariottilab.bsky.social @geneticsub.bsky.social

Mariotti Genomics Lab@mariottilab.bsky.social · 2mo ago

🧬 Excited to share our preprint: Regulatory landscape of widespread stop codon readthrough (SCR) in Drosophila 🪰 Stop codons supposedly mark the end of protein synthesis. Sometimes they don’t: >1,000 Drosophila genes undergo SCR, a process wherein translation continues past the stop.

Regulatory landscape of widespread stop codon readthrough in Drosophila

In stop codon readthrough (SCR), ribosomes continue to translate past the stop. While programmed SCR is rare in mammals, it appears remarkably widespread in insects, yet its regulation and biological ...

doi.org

Mariotti Genomics Lab@mariottilab.bsky.social · 7mo ago

We're happy to share that our article "Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases" has been published: journals.plos.org/ploscompbiol... #bioinformatics #recoding #selenoproteins #geneannotation Collab with @rodericguigo.bsky.social

Overcoming the widespread flaws in the annotation of vertebrate selenoprotein genes in public databases

Author summary Genome annotations serve as a map of the genetic information encoded in our DNA. They are essential for numerous applications, working as a reference to interpret high throughput experi...

journals.plos.org

Genetics UB@geneticsub.bsky.social · 7mo ago

🧬 Year after year, @geneticsub.bsky.social remains firmly committed to continuous improvement. 🥇 This year has been highly rewarding and we look forward to the opportunities that 2026 will bring. 🎉 Thanks to all our members for your hard work and dedication! Together, we make a strong team.

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Mariotti Genomics Lab@mariottilab.bsky.social · 8mo ago

Bioinformaticians, spread the word! Pyranges v1 is here: a Python framework for ultrafast sequence interval operations (aka genome arithmetic). Documentation (installation, tutorial, API, how-to-pages): pyranges1.readthedocs.io Preprint: doi.org/10.64898/202... #bioinformatics #genomics #python 🧬💻🐍

Pyranges v1: a Python framework for ultrafast sequence interval operations

Sequence interval algebra is key to modern bioinformatics. Pyranges v1 offers a Python Pandas-based interface to a comprehensive palette of Rust-powered operations (e.g., overlap, count, slice interva...

doi.org

Mariotti Genomics Lab@mariottilab.bsky.social · 9mo ago

I'm happy to announce that I obtained a tenured position at @geneticsub.bsky.social @biologiaub.bsky.social ! 🧬🎉

Genetics UB@geneticsub.bsky.social · 9mo ago

🔊We are excited to announce a new Associate Prof (Prof Agregat) at @geneticsub.bsky.social 👏Congratulations to Dr.Marco Mariotti on his new position!He leads the "Comparative Genomics of Gene expression Lab",where his team works to investigate the process of gene expression and protein synthesis.

Mariotti Genomics Lab@mariottilab.bsky.social · 11mo ago

Here's an interesting paper @natmethods.nature.com introducing the term "Translon", filling a terminology gap in the field of gene expression. Kudos to Pasha Baranov for leading this initiative and gathering many contributors (including myself) for an healthy discussion on fundamental principles 👏

Jack Tierney@jackatierney.bsky.social · 11mo ago

Many transcriptome regions are translated but not known to encode proteins. They remain poorly annotated and thus under studied, partly due to the lack of terminology for these features. In @natmethods.nature.com we propose using "Translon" for any region decoded by the ribosome

Snapshot of the Correspondence titled 'Translon: a single term for translated regions'
Mariotti Genomics Lab@mariottilab.bsky.social · last yr.

We had lots of fun at the #FestaCiènciaUB with our workshop on gene expression! It seems participants loved it too ❤️🧬! Thanks to the lab members, including the iGem UB team, and all the organizers of the event 👏

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Genetics UB@geneticsub.bsky.social · last yr.

🧬 Un any més, la secció de @geneticsub.bsky.social es suma a la #FestaCiènciaUB amb un munt de tallers que podeu visitar fins demà a la @ub.edu 🎉 No us ho perdeu!

Mariotti Genomics Lab@mariottilab.bsky.social · last yr.

Today and tomorrow you will find us at the Science Fest of UB #FestaCiènciaUB ! Come and play to our workshop and learn to decipher the code of life 🧬. Free entrance!

Unitat de Cultura Científica i Innovació de la UB@ubdivulga.bsky.social · last yr.

Aprendre com funciona el codi de la vida 🧬mai havia estat tan divertit! Entendreu que són l'ADN, l'ARN i les proteïnes amb les vostres pròpies mans a la #FestaCiènciaUB. @geneticsub.bsky.social @biologiaub.bsky.social 👉 web.ub.edu/web/laubdivu...