💬 Invited Commentary: Autonomous #Oxygen titration in hospitalized patients with acute hypoxemic respiratory failure increased time in normoxemia to 85% vs 63% with usual care and reduced time in hypoxemia to 2.0% vs 3.6%. #MHSRS2026 ja.ma/4bq4hYf

Presented today at #MHSRS2026: Among acutely ill adults receiving supplemental oxygen, #AutonomousOxygenTitration increased time in normoxemia and decreased time in hypoxemia vs usual care. ja.ma/3TTVGa9

Food-specific IgE panel testing should not be ordered without a clinical history suggestive of IgE-mediated #FoodAllergy. Sensitization alone does not establish diagnosis and may contribute to unnecessary dietary restriction, patient harm and avoidable costs. Learn more: ja.ma/4wxEFAW

A randomized trial in rural #NavajoNation found that a culturally tailored meal program for adults with #HeartFailure reduced hospitalizations or emergency visits and improved food insecurity, quality of life, and blood pressure. ja.ma/45xxsoH

A large cluster randomized trial found no reduction in winter respiratory infection rates among care home residents with the use of portable high-efficiency particulate air filters, compared with standard infection prevention measures. ja.ma/4w4m0Mf

💬 Viewpoint: Most lethal #zoonotic #viruses, including Andes virus, lack sufficient transmissibility for global spread. Balanced public health communication is essential to prevent undue alarm. ja.ma/3SZ7fwk

Cluster RCT: On-site #POC-RMPCR in nursing homes did not reduce outbreak size or frequency, but reduced ED transfers and enabled faster #antiviral therapy compared to standard off-site testing. ja.ma/3QJe3O4

A large sibling-matched cohort study in Hong Kong found no evidence of an association between prenatal paracetamol (acetaminophen) exposure and risk of #Autism or #ADHD in offspring when accounting for unmeasured familial confounding. ja.ma/4eZLjbL

An 8-week telehealth mindfulness group medical visit program for adults with #LowBackPain produced modest but sustained improvements in pain intensity and interference at 6 and 12 months vs usual care. ja.ma/3SumjSz

Asynchronous electronic screening prior to #telemedicine visits improved completion and detection rates for unhealthy alcohol use among #veterans in primary care compared with usual staff-administered screening. ja.ma/4vGDRt6

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4g2acpz

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4vhq2kF

In a randomized trial, higher financial incentives eliminated racial enrollment disparities in a smoking cessation trial, but did not affect gaps by sex, age, or education. ja.ma/4eszegc

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4g2abC1

Multilevel stewardship helped reduce inappropriate anticoagulation-antiplatelet therapy, especially among patients with #coronary #artery #disease, according to Jacob E. Kurlander, MD, MS, and C. Seth Landefeld, MD. 🎧 Listen: ja.ma/3SsdNDq

Multilevel Stewardship Intervention for Use of Anticoagulation-Antiplatelet Therapy

Interview with Jacob E. Kurlander, MD, MS, author of Multilevel Stewardship Intervention for Use of Anticoagulation-Antiplatelet Therapy, and C. Seth Landefeld, MD, author of Deprescribing Inappropriate Medicines Across a Health System—Can We Improve the Care of Both Patients and Physicians? Hosted by Ilana Richman, MD.

ja.ma

In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. ja.ma/4gxL8GV

Among US adults, 2024–2025 COVID-19 vaccination was associated with a 26% lower risk of COVID-19 ED/UC visits, 35% lower risk of hospitalization, and 41% lower risk of critical illness, with effectiveness declining >6 months post vaccination. ja.ma/3QuGHlE

Among older adults after #surgery, postoperative #delirium was independently associated with long-term #cognitive decline; rehospitalization did not mediate this association. ja.ma/4vnBefJ

Among US veterans, the 2024-2025 COVID-19 vaccine was associated with a 37.7% lower risk of COVID-19–associated #MACE, with the largest benefit in adults >75 years and those with comorbidities. ja.ma/4aAEWKt

In adults at risk for chronic low back pain, clinician-supported biopsychosocial self-management was more effective than #medical care at reducing LBP impact and chronicity, while #spinal manipulation showed no added benefit. ja.ma/4eg0PQs

#Arthritis is a leading cause of pain and disability that affects nearly one-third of older US adults, many have inflammatory arthritis. 💡 This Clinical Insights discusses inflammatory arthritis in older adults and offers practical guidance. ja.ma/4a6Cf3p

#Arthritis is a leading cause of pain and disability that affects nearly one-third of older US adults, many have inflammatory arthritis. 💡 This Clinical Insights discusses inflammatory arthritis in older adults and offers practical guidance. ja.ma/4a6Cf3p

A community health worker-led, telehealth #diabetes intervention improved HbA1c, cholesterol, and ADA guideline adherence vs usual care in low-income Hispanic adults, addressing 87% of participant concerns via a structured feedback loop. ja.ma/3QuDtyy

Among older adults after surgery, postoperative delirium was independently associated with long-term cognitive decline; rehospitalization did not mediate this association. ja.ma/4umBqui

Older adults living alone with cognitive impairment are at elevated risk for medication-related harm due to barriers at multiple levels, including lack of reminders, regimen complexity, and unwitnessed adverse effects. ja.ma/4xuvzGn

From JAMA: In this observational study of adults in Stockholm, measured GFR (mGFR) values below 90 mL/min/1.73 m² were associated with progressively higher rates of #mortality, #kidney failure, #heart failure, acute kidney injury, and major #cardiovascular events. ja.ma/4o8zzHY

From @jama.com: Among adults with advanced chronic #kidney #disease (#CKD) stage 4 or 5 or on #dialysis, low-dose rivaroxaban did not lower #cardiovascular risk but did raise major bleeding rates, supporting guideline caution in this group. ja.ma/4uMNZjE

In adults at risk for chronic low back pain, clinician-supported biopsychosocial self-management was more effective than #medical care at reducing LBP impact and chronicity, while #spinal manipulation showed no added benefit. ja.ma/4vn5vLk

A financial incentive for hypertension control increased guideline-adherent blood pressure remeasurement but did not improve overall control or health outcomes, highlighting potential unintended harms among patients with borderline hypertension. ja.ma/4e30pgh

Older adults living alone with cognitive impairment are at elevated risk for medication-related harm due to barriers at multiple levels, including lack of reminders, regimen complexity, and unwitnessed adverse effects. ja.ma/4ohJwTT