Jacob Brandenburg

@jbrandenburg13.bsky.social

Global Marketing Manager - Plant + Animal Sciences @PacBio | Agrigenomics Enthusiast 🧬 | Wisconsin-based | Opinions my own

Introducing CiFi from #PacBio and UC Davis! It combines 3C with HiFi long reads to generate chromosome-scale, haplotype-resolved assemblies from a single SMRT Cell. Minimal samples, fewer runs, and maximum insight into complex genomes. Discover CiFi with us at #PAG33. Details: bit.ly/4qLpVvb

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Hi-C users, the wait is finally over! 🙌🏽 CiFi now enables Hi-C with #HiFisequencing. Short-read Hi-C struggles when it comes to repetitive and low-complexity regions. #PacBio HiFi rises to the challenge with better accuracy and lower input requirements. Congrats Megan and UC Davis team!

Megan Dennis@mydennis.bsky.social · 2y ago

Check out our new preprint describing CiFi - a method that couples 3C and PacBio HiFi sequencing with low input requirements. We apply it to human GM12878 to better characterize chromatin across repetitive regions, as well as single insect samples (a mosquito and a Mediterranean fruit fly).

The future of trait mapping is HiFi low pass sequencing! Amazing pre-print from Dr. Kendall Lee out of the Clevenger lab. Their work is going to revolutionize genomic based breeding. #PacBio #HiFisequencing

PacBio@pacbio.bsky.social · 2y ago

Explore how low-pass #HiFisequencing is transforming plant and animal genomics. 🌱🌍 Discover its potential to revolutionize breeding with precise trait mapping at a lower cost per insight, addressing agriculture's toughest challenges. Blog here: bit.ly/4h7AaFA #PacBio