4️⃣ Contributions ✨The findings open new avenues for developing personalised therapies for patients with leptomeningeal diseases, with cancer cells in CSF 🔝Led by CNAG: @paulanietog.bsky.social (first author), @hoheyn.bsky.social and @jcnietos.bsky.social (corresponding authors), and Ginevra Caratù

4️⃣ Contributions ✨The findings open new avenues for developing personalised therapies for patients with leptomeningeal diseases, with cancer cells in CSF 🔝Led by CNAG: @paulanietog.bsky.social (first author), @hoheyn.bsky.social and @jcnietos.bsky.social (corresponding authors), & Ginevra Caratù

📻¡Salimos en @aragonradio.bsky.social! El periodista Marcos Ruiz entrevista a @jcnietos.bsky.social, inmunólogo en CNAG y autor de nuestra nuestra última investigación: descodificamos el líquido cefalorraquídeo para ayudar a pronosticar las enfermedades cerebrales ➡️ www.cartv.es/aragonradio/...

Integrative CSF profiling identifies disease-specific immune responses in leptomeningeal disease @cp-cellrepmed.bsky.social www.cell.com/cell-reports...

Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells. https://www.nature.com/articles/s41591-025-04126-3

Interpretable inflammation landscape of circulating immune cells - Nature Medicine

Including data from 1,047 patients across 19 inflammatory diseases, a new atlas presents a comprehensive model of inflammation in circulating immune cells.

nature.com

📺 Our cellular atlas of inflammation on TV! Discover this landmark study, including the analysis of 6.5 million blood cells and serving as the foundation for an AI tool to advance diagnosis 👉 @rtvenoticias.rtve.es, with @jcnietos.bsky.social: youtu.be/yX1zTamxf3A 🔗 www.cnag.eu/news/first-c...

Interview on RTVE about our study on the first cellular atlas of inflammation

Discover this landmark study, which includes the analysis of over 6.5 million blood cells and served as the foundation for developing an AI tool to advance diagnosis Interview: Dr Juan Nieto,…

youtu.be

5️⃣ Next steps Researchers are now working on standardising protocols and integrating the atlas into clinical practice. A groundbreaking study led by Drs @hoheyn.bsky.social, @jcnietos.bsky.social, @dmaspero.bsky.social, @saguilarfer.bsky.social, & team, this effort is part of the EU-funded Doctis

🌍 Meet Dr @jcnietos.bsky.social, immunologist at #CNAG, at #IUIS2025! 🗣️ He’ll give an oral abstract presentation on “Interpretable Inflammation Landscape of Circulating Immune Cells” 📌 @iuis-online.bsky.social (Vienna, Austria) 🗓️ Thursday, August 21 | 10:30 – 12:00 ℹ️ iuis2025.org

🔬An aggressive #ChildhoodCancer case opens new avenues for advanced cell therapies. ✍️ #IRBBarcelona, @cnag-eu.bsky.social, @sjdhospitalbarcelona.org 📰 Annals of Oncology Read more here ➡️ bit.ly/40Ut5lC 📌 DOI: 10.1016/j.annonc.2025.05.530 #IRBScience 🧪

Don't miss this chance to engage with the experts as they present single-cell research for complex diseases. Learn how this technology is being used to uncover new insights into type 2 diabetes, brain tumors, and leptomeningeal disease. Register here: www.workcast.com/register?cpa...

Big thanks to @paulanietog.bsky.social , @piazeiner.bsky.social , @hoheyn.bsky.social & the team for this collaboration! 🚀 Our study shows how CSF liquid biopsy mirrors CNS tumor immunity using single-cell & spatial transcriptomics. Insights into T cell responses, myeloid dominance & biomarkers!

Paula Nieto@paulanietog.bsky.social · 2y ago

📢 SUPER EXCITED to share our latest preprint: Decoding the immune response in leptomeningeal disease through single-cell sequencing of cerebrospinal fluid Incredible work and collaboration from @jcnietos.bsky.social @piazeiner.bsky.social @hoheyn.bsky.social and others. biorxiv.org/content/10.110…