Jim Morrissey

@jhmorrissey.bsky.social

Professor at University of Michigan Medical School in Ann Arbor. My lab does NIH-funded research on the biochemistry of blood clotting, with relevance to bleeding disorders and thrombosis.

Delighted to share that my historical coming-of-age novel, THEA, was a winner in the 2025 Page Turner Awards (Best Historical Fiction & Character Architect Award) — and I also got to work with the amazing Nicole Fikes on the audiobook version, which just debuted. www.audible.com/pd/B0GQ1JZY6...

Thea

Check out this great listen on Audible.com. – 2025 Page Turner Book Award winner for Best Historical Fiction & Character Architect Award --------------------------------------- Oklahoma City, 1925 ...

audible.com

Delighted that our cryo-EM structure of the enzyme that triggers blood clotting (TF/FVIIa) was featured on the cover of Blood, revealing a new explanation for TF encryption! Josepha Sezdro worked closely with Amanda Photenhauer in Melanie Ohi's lab to solve this structure. doi.org/10.1182/bloo...

Cryo-EM structure of the tissue factor/factor VIIa complex with a factor X mimetic reveals a novel allosteric mechanism

Key PointsXK1 interacts with TF/FVIIa via the FVIIa protease domain and TF exosite, with much of the FX light chain making no contact with TF/FVIIa.A novel

doi.org

Paracetamol remains an important option to treat pain or fever in pregnant women. Following rigorous assessment of the available scientific data, we find no evidence that taking paracetamol during pregnancy causes autism in children. Read more 👉 www.ema.europa.eu/en/news/use-...

Use of paracetamol during pregnancy unchanged in the EU | European Medicines Agency (EMA)

Paracetamol medicines can be used in pregnancy, in accordance with official recommendations

ema.europa.eu

Very cool to see the cover of Blood Advances featuring our simulation of the enzyme that triggers blood clotting (tissue factor/factor VIIa), assembled on a membrane surface and bound to its favored substrate, factor X. Great collaboration with Emad Tajkhorshid’s group at Univ. of Illinois!

Blood Journals Portfolio@bloodjournals.hematology.org · 2y ago

🚨New Blood Advances issue out now featuring Inside Blood Advances: How donor age affects RBC deformability in storage Testicular follicular lymphoma: let me count the ways The transplant debate: defining innovation for sickle cell https://buff.ly/435x7JN #bloodjournals

Abstract deadline coming soon! -- March 1 for oral presentations; April 1 for poster-only. PolyP-2025 – Conference on Polyphosphate Biology – May 20-23, 2025 at the Univ. of Michigan campus. Early (reduced-cost) registration deadline is February 28. Full meeting info: polyp2025.org

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