Fantastic talk by Gemma Leon on TF+ Tcell population in inflammatory bowel disease @rogerpreston.bsky.social @rcsi.bsky.social #ISTH2025
Roger Preston
@rogerpreston.bsky.social
Interested in blood clotting, protein engineering and immunity. Lab website: www.prestonlab.ie
Kicking off #ISTH2025 with the first falk from RSCI by @aislingrehill.bsky.social on fibrin on trained immunity-associated myeloid cell hypercoagulability @rogerpreston.bsky.social @rcsi.bsky.social
📢 @jthjournal.bsky.social is proud to announce the recipients of the 2025 JTH Editors’ Awards! These prestigious awards honor six outstanding early career investigators for their top articles in thrombosis and hemostasis. Join us in congratulating the winners🎉 and learn more here: bit.ly/4lc2pFR
According to new RCSI research, immune cells that 'remember' past inflammation could increase the risk of blood clots in the long term. The 'shortened fuse' in these cells may contribute to a higher blood clot risk in inflammatory conditions. Read more 🔗 www.rcsi.com/dublin/news-... #RCSIdiscover
Pleased to share our latest paper in Science Advances on myeloid cell ‘trained hypercoagulability’! 🚀 Project led by @aislingrehill.bsky.social - huge thanks to our collaborators & funders @tcddublin.bsky.social @researchireland.bsky.social CHI and HRB Ireland tinyurl.com/df4fsrrx
Trained immunity causes myeloid cell hypercoagulability
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Thrilled to share new work led by @jieyang437.bsky.social in the lab published today in @Nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. @Cambridge_Uni @CRUKCamCentre rdcu.be/eci1U
New publication from our group in @naturecomms.bsky.social led by Gemma Leon @rcsi.bsky.social Thanks to our collaborators at @tcddublin.bsky.social, CHI Crumlin, and to @researchireland.bsky.social and Children’s Health Ireland for funding. Open access link: rdcu.be/d93ds
Tissue factor-dependent colitogenic CD4+ T cell thrombogenicity is regulated by activated protein C signalling
Nature Communications - Patients with inflammatory bowel disease (IBD) have increased risk for venous thromboembolism, but mechanistic insight is still lacking. Using both mouse experimental...
rdcu.be
Many academics point to bioRxiv as “the one thing improving science publishing”. If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2