Josie Maidment

@jmaidment.bsky.social

Postdoctoral scientist @phimresearch.bsky.social) &‬ @cbsmontpellier.bsky.social Biochemical/structural studies of proteins to understand plant disease/immunity & improve crop health 🌾🌱 She/her. Views my own.

Profile of @plantphys.bsky.social EIC Yunde Zhao & RUBY reporter his lab developed; free for use in academic labs & classrooms. “RUBY is making a difference in so many ways because we opened it up to all of science". "Fundamental research is crucial because it can lead to unexpected discoveries.”

Seeing Red: A UC San Diego Invention is Transforming the Way Scientists Track Genes

UC San Diego biologists have created a transformative new way to monitor genes. The game-changing tool known as RUBY is an inexpensive, easy-to-use technology that allows researchers to visualize gene...

today.ucsd.edu

I am looking for a (bio)chemist to join the lab and help us making affinity-based probes for proteases! The project is truly interdisciplinary with a strong computational chemistry component, peptide synthesis and plant biochemistry! Text me if interested and please spread the word!

IPB Halle@ipbhalle.bsky.social · last yr.

📣We offer a #PhDposition @dfg.de-funded #RTG2670 BEAM: "Beyond Amphiphilicity - Self-Organization of Soft Matter via Multiple Noncovalent Interactions" with @marischuster.bsky.social. 🔗More: www.ipb-halle.de/en/career/jo... 📅Apply now! #MolecularModelling #Proteases #SciJobs #PhDjobs

🎉 Exciting news during #2025ISMPMI Our AlphaFold sensor vs helper NLR paper is now published in @newphyt.bsky.social‬! Big thanks to the reviewers for their constructive feedback 🙏 📖 Check out the peer-reviewed version here 👇 🔗 nph.onlinelibrary.wiley.com/doi/10.1111/... bsky.app/profile/yusu...

Can AI modeling of protein structures distinguish between sensor and helper NLR immune receptors?

Click on the article title to read more.

nph.onlinelibrary.wiley.com

Yu Sugihara@yusugihara.bsky.social · 2y ago

Please check our latest paper on using @deep-mind.bsky.social AlphaFold 3 to study NLR immune receptors. Here we use AI-guided structural modelling to distinguish between sensor and helper NLRs! 👇🧵 (1/10) #EvoMPMI #NLRbiology #PlantPath #PlantSci doi.org/10.1101/2024...

#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible! Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵 www.biorxiv.org/content/10.1...

mamp-ml: A deep learning approach to epitope immunogenicity in plants

Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...

biorxiv.org