Delighted to see our latest paper out in @natgenet.nature.com ! The brilliant @jhamley98.bsky.social developed MCCv, allowing chromatin architecture to be visualised at base-pair resolution for each allele—a powerful way to identify functional genetic variants. www.nature.com/articles/s41... 🧵

Just gonna leave this here while it’s still hot off the press 🤩 On the Structure and Function of Transcription Bodies Maciej A. Kerlin Shivali Dongre @shivalidongre.bsky.social Eleonora Perego Martino Ugolini Nadine Vastenhouw @nvastenhouw.bsky.social www.annualreviews.org/content/jour...

On the Structure and Function of Transcription Bodies

Transcription is a key process in the life of cells. In the 1990s, cell biologists observed that transcription often takes place in discrete transcription bodies in eukaryotic nuclei, which has sparke...

annualreviews.org

Come join us April 2027 for the next instalment of the EMBL Chromatin and Epigenetics meeting. Great invited speakers and lots of talks selected from abstracts! It will be a fantastic meeting (despite the egregious nucleosome images...)

EMBL Events@events.embl.org · last wk.

Registration is now open for the EMBL Conference 'Chromatin and epigenetics' 🧬 Explore how epigenetic mechanisms shape human health and disease, and hear renowned speakers discuss the latest advances in the field #EMBLChromatin Submit your abstract by 19 January: s.embl.org/chr27-01-bl

Such a pleasure to share my work at the inaugural Oxford chromatin meeting! Really enjoyed - especially the extended discussion over the drink 🥂 Thank you for organising @fitz-james-lab.bsky.social and @mariekewens.bsky.social!

Fitz-James Lab@fitz-james-lab.bsky.social · last wk.

🧪A pleasure to have hosted the first meeting of the Oxford Chromatin Club with @mariekewens.bsky.social yesterday! Great talks from Hoa Vo (Physics) on CMG progression and @joyjoychoi.bsky.social (@oxfordbiochemistry.bsky.social) showing the incredible CryoET work from her new preprint (link below).

It's so cool to see more papers showing unexpected findings describing active regions are not necessarily super open, with newer techniques with higher resolution.

Kazuhiro Maeshima@kazu-maeshima.bsky.social · 2w ago

🧬 Highly related @natgenet.nature.com paper from @binzmit.bsky.social group, using nucleosome-resolution chromatin modeling: Euchromatin forms condensed domains with short active regions on the surface www.nature.com/articles/s41... Congratulations! 🎉

🏆 Biochemist Martin Jinek is the winner of the Swiss Science Prize #MarcelBenoist 2026, considered the Swiss #Nobel Prize. He contributed to the development of molecular scissors, namely CRISPR-Cas9 technology. Read more ➡️ sohub.io/3hs4

After 35 years, the structural biologist Christoph Müller has a new title: Emeritus Scientist. His career at EMBL is marked by lauded research and important mentorship. Now he begins his next chapter. www.embl.org/news/people-...

What I’ve Learned: Christoph Müller | EMBL

Christoph Müller shares his thoughts on structural biology and from the many experiences and wisdom collected over a 35-year career.

embl.org

🧬 Our “Behind the Paper” is now online at Nature Communities: “Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.” 📖 A short story behind our recent @natgenet.nature.com paper. communities.springernature.com/posts/active... www.nature.com/articles/s41...

Congratulation!!

Max Planck Institute of Biochemistry@mpibiochem.bsky.social · 3w ago

Read the latest publication “Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1” from the Müller Research Group, published in Nature Structural & Molecular Biology. ❕ Publication: www.nature.com/articles/s41... ❕Press Release: www.biochem.mpg.de/a-molecular-... #PRC1

Excited to share our new preprint on in situ chromatin structure of the inactive X chromosome in differentiated female mouse embryonic stem cells. www.biorxiv.org/content/10.6... 🧵1/8

Come join us at the @biozentrum.unibas.ch as Professor in Climate Biophysics. Blue-sky research, inspiring colleagues, and generous support.

Ben Engel@cellarchlab.com · 3mo ago

Super excited to launch this search for a new endowed professor at the @biozentrum.unibas.ch! Join us to build a research cluster in Climate Biophysics! 🌍🌊🌾🔬🧪 This is a unique opportunity to create a community in Basel🇨🇭working together on this timely topic! ⏳🌡️ Questions? Please reach out! 👩‍🔬👨‍🔬

This is so beautiful! CTCF got such a creative way to organise chromatin!

Seychelle Vos@voslab.org · 8mo ago

🧪🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...

Unicore identifies single-copy protein structures across genomes using Foldseek, bypassing slow structure predictions by utilizing 3Di predictions from ProstT5, enabling rapid phylogenetic inference at the tree-of-life scale. 1/n 📄 www.biorxiv.org/content/10.1... 💾 github.com/steineggerla...