🤠 youtu.be/BuiEVOSTbN4

Google kills AlphaFold. So much for AI curing cancer

YouTube video by Pivot to AI

youtu.be

Olivia Guest · Ολίβια Γκεστ@olivia.science · 2mo ago

If you're anti AI & making claims that some of the models under the AI umbrella are ok because they seem to be serving scientific goals, then you fell for a type of hype. One from the 2010s; stats models aren't blessed by their use in science and they can erode our thinking. bsky.app/profile/oliv...

Science funding has still not reached gender equality: "Projects led by male PIs received roughly twice the mean funding compared to female PIs." www.sciencedirect.com/science/arti...

flying UMAPs

Jonathan Slater@jonathanslater.bsky.social · 2w ago

Good morning Murmuration and Blue Sky

🔥 New Night Science Podcast episode! What can comedy teach us about scientific discovery? With stand-up comedian and former research scientist Sarah Adelman, we discuss the surprising parallels between jokes and discoveries! open.spotify.com/episode/0zG2... podcasts.apple.com/us/podcast/n...

Fantastic idea Julien! @redpenblackpen.bsky.social, would you like to come on as a guest on the night science podcast? podcasts.apple.com/us/podcast/n...

Night Science

Natural Sciences Podcast · Updated Weekly · Where do ideas come from? In each episode, scientists Itai Yanai and Martin Lercher explore science's creative side with a leading colleague. New episodes c...

podcasts.apple.com

I guess one difference between Jim Crow then and Jim Crow now is that we have cool graphics to show how it's done.

Super happy to see this out. 😎

Bgee database@bgee.org · 2mo ago

New preprint, where we present scFAIR, a consortium of single-cell data resources that has developed a unified metadata schema and common curation framework to improve the FAIRness of scRNA-seq data. www.biorxiv.org/content/10.6...

"Bioconductor Spatial Data and Image Analysis Hackathon" https://doi.org/10.37044/osf.io/9ej32_v1 "We report the outcomes of the Bioconductor Spatial Data and Image Analysis Hackathon, held in Venice, Italy in April 2026. Twenty-seven researchers and […] [Original post on fediscience.org]

Many results, new or improved packages, and future directions in this report on the Bioconductor Spatial Data and Image Analysis Hackathon that took place in Venice in April 2026. osf.io/preprints/bi...

When the location of a conference is announced, can we take the habit of first highlighting accessibility by train rather than starting by highlighting airports?

Thermo Fisher now has a page up in response to our observations. They flatly deny that images were manipulated or fabricated while repeating that images were "optimized for presentation and clarity on the website", no lie, six times. www.thermofisher.com/us/en/home/l...

Reese Richardson@reeserichardson.bsky.social · 2mo ago

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

No, they were not

We are live!!! The program starts at 9 in Finnish time. Watch European Bioconductor Conference for free: utu.zoom.us/j/62224935664 #EuroBioC2026 #Bioconductor

Now accompanied by a lovely write-up from our communications office @unibas.ch - thanks @angelikajacobs.bsky.social 🙏 ! : www.unibas.ch/en/News-Even...

You are what you eat: how diet drives evolution

A University of Basel study shows how different diets shape the evolution of intestinal cells in cichlid fishes.

unibas.ch

Tschopp Lab@tschopplab.bsky.social · 3mo ago

One of my dream projects, ever since joining here in Basel, out now in @nature.com : single-cells 🤝 eco-morphological proxies rdcu.be/fiyso How cells and tissues adapt to dietary niches... Thanks and congrats to Antoine, Walter, and all the other co-authors for this great collaboration!! 🙏🥳

Did I submit 3 papers or revisions in the last hour? Maybe. When projects end, it's sad to see people go, but great to see results come out. Find all of our work at @biorxiv-evobio.bsky.social @biorxiv-genomic.bsky.social

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...

How much of Thermo Fisher’s antibody data has been manipulated?

We’ve documented more than 100 instances of apparent data manipulation in Thermo’s catalog

reeserichardson.blog

Beyond the mean: genetic control of gene expression fidelity and dispersion www.biorxiv.org/content/10.6...

Finally found time to try mapping/demultiplexing a 10X Flex dataset (v1) using STARsolo github.com/alexdobin/ST... It's quite a versatile tool and we've been using for Chromium 10X 3'/5', w/ and w/o ADT/HTOs, PARSE-seq, BD Rhapsody, even for bulk RNA-seq with BRB-seq, so I wanted to give it a try!

Very pleased to be hosting this today. Two great speakers & a chance for the Bioconductor community throughout the Asia-Pacific to come together. Registrations are still open if you're interested in #rstats package development and bioinformatics 🧬 🖥️ 4pm AEST with relevant time zones on the site

Bioconductor@bioconductor.bsky.social · 3mo ago

📢 We’re excited to launch the BiocAsia Seminar Series, bringing together the Asia-Pacific Bioconductor community through shared learning and connection. The series will begin with two speakers: Prof Matt Ritchie & Dr Helena Crowell 📅 12 May ⏰ 4:00-5:00 pm AEST 🔗 Register to attend: bit.ly/42gczgl

Just grab the latest: * simpleaf (github.com/COMBINE-lab/...; also available via bioconda) or * cyto (github.com/arcinstitute...; preprint here: www.biorxiv.org/content/10.6..., not my work, but the tool seems great and the devs are very solid) And you're off to the (much faster) races! 2/2

GitHub - COMBINE-lab/simpleaf: A rust framework to make using alevin-fry even simpler

A rust framework to make using alevin-fry even simpler - COMBINE-lab/simpleaf

github.com

This is a very cool demonstration of the possibilities of 10x Flex link.springer.com/article/10.1...! But did you know that you can get near identical results MANY TIMES faster than CellRanger by processing flex data with piscem/alevin-fry or cyto? Both highly efficient & fully, truly open source?/2

10 × Genomics Flex Gene Expression is a powerful tool for single-cell transcriptomics of xenografts models - Genome Biology

The 10 × Genomics Flex Gene Expression protocol is a probe-based method that profiles fixed or frozen material, simplifying sample handling before scRNA-seq. Although probes exist only for human and m...

link.springer.com

Another experience with a coding agent in support of “Great if you know what you are doing, but you risk getting junk if not”. I had some R/quarto scripts in which I wanted to replace all assignment = operators with <- (which looks like ← in fonts with ligatures). Subtlety #1 is... 1/4

« Les espèces animales commercialisées ont plus de risques de partager un pathogène avec l’humain » Cleo Bertelsmeier, biologiste, s’inquiète de l’explosion du commerce des animaux exotiques. www.lemonde.fr/sciences/art... #MicroSky #zoonosis #zoonose #pathogens

Cleo Bertelsmeier, biologiste : « Les espèces animales commercialisées ont plus de risques de partager un pathogène avec l’humain »

Dans un entretien au « Monde », la chercheuse s’inquiète de l’explosion du commerce des animaux exotiques. A ce jour, aucune convention n’encadre leur vente, malgré le danger potentiel qu’ils représen...

lemonde.fr

#RIP Pierre Chambon (1931-2026) via @alainberetz.bsky.social one of the last giants in biology: PARP, nuclear receptors, RNA Pol II, nucleosome, promoters, split genes

Il était 10ème hier encore. Raoult se voyait Nobel, il aura finalement rejoint le top 8 des scientifiques les plus rétractés. La gloire.

Fabrice FRANK@fabricefrank.eurosky.social · 3mo ago

70ème rétractation pour l'IHU La 58ème pour Didier Raoult qui devient le 8ème scientifique avec le plus de rétractations.

Check it out! 👇With growing pressure to phase out animal research, we argue that doing so now, when scientists are just beginning to address sex differences after decades of male-biased research, risks embedding existing knowledge gaps into "animal-free" biomedicine. www.nature.com/articles/s41...

Free and open-source images, icons, and tools for creating scientific illustrations doi.org/10.59350/5zt... 🧪

Free and open-source images, icons, and tools for creating scientific illustrations

Phylopic, NIH Bioart, Bioicons, Scidraw, Open Science Art, Health Icons, Servier Medical Art, Biodiversity Heritage Library, the Noun Project, Segment Anything, Excalidraw, draw.io, Biographics

doi.org

I just repeated the analysis for grants in fiscal year 2026. I found 98 grants with title changes upon administrative (non-competitive) renewal. Here is the removed word cloud for fiscal year 2026. 4/5

Including the new Rega package from my colleagues Igor Cervenka, Athimed El Taher and Robert Ivanek: bioconductor.org/packages/rel... Are you struggling to deposit human sensitive data to the EGA database? Give it a try!

Rega

The European Genome-phenome Archive (EGA) provides long-term storage and controlled sharing of personally identifiable genetic data. The Rega package offers a streamlined and extensible R interface to...

bioconductor.org

Bioconductor@bioconductor.bsky.social · 3mo ago

🚀 We’re excited to share the release of Bioconductor 3.23, featuring: ✅2418 software packages (94 new) ✅437 experiment data packages (5 new) ✅928 annotation packages ✅8 books (2 new) ✅28 workflows 🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...

Bioconductor 3.23 is released! Thanks to the core team for all the hard work that goes into a release, and to the package reviewers. The lab has a bunch of updates in here that I'll post in 🧵 over the next few days:

Bioconductor@bioconductor.bsky.social · 3mo ago

🚀 We’re excited to share the release of Bioconductor 3.23, featuring: ✅2418 software packages (94 new) ✅437 experiment data packages (5 new) ✅928 annotation packages ✅8 books (2 new) ✅28 workflows 🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...