POINTseq, now out in Neuron after peer review. Read it. There are barcodes, viruses, and dopamine. Congrats to @hyopilkim.bsky.social on leading our lab's first published paper!
Justus Kebschull
@justuskebschull.bsky.social
Neuroscientist of sorts. Head of the Kebschull Lab at Johns Hopkins BME. https://www.kebschull-lab.org/
For all cerebellum and cerebellar nuclei aficionados: A cre line specifically tagging the large, excitatory B-cells in the mouse cerebellar nuclei: www.biorxiv.org/content/10.6... Lmk if you want to use it!
biorxiv.org
New from the lab: BARseq3! Barcodes + high efficiency spatial transcriptomics and translatomics in the same cells, or just a nice spatial transcriptomics assay. All in a modular, expandable system to enable truly multimodal measurements. Check it out: www.biorxiv.org/content/10.6...
biorxiv.org
“Specific expansion of motor cortical projections in a singing mouse” Great new work by @arkarupbanerjee.bsky.social E. Isco @cliffscience.bsky.social @xmikezheng20.bsky.social @tonyzador.bsky.social & colleagues on the neural basis of vocal dexterity, now out in @nature.com 🧪🧠
Specific expansion of motor cortical projections in a singing mouse - Nature
High-throughput barcoded neuroanatomy of two closely related rodent species with divergent vocalizations reveals differences in long-range projection motifs in the brain that may s...
nature.com
Just published in JOSS: 'DART: A GUI Pipeline for Aligning Histological Brain Sections to 3D Atlases and Automating Laser Microdissection' https://doi.org/10.21105/joss.09109
As a longtime fan of cool papers in @currentbiology.bsky.social, I am really thrilled to see this out! This study sets the stage for understanding the origins of novel (vocal) behaviors. Big shout out to the main architects of this work @xmikezheng20.bsky.social and @cliffscience.bsky.social
Great @currentbiology.bsky.social study by @xmikezheng20.bsky.social @cliffscience.bsky.social @arkarupbanerjee.bsky.social 🧪🧠🐭🎶 Vocal repertoire expansion in singing mice by co-opting a conserved midbrain circuit node www.cell.com/current-biol...
I am recruiting graduate students for the experimental side of my lab @mcgill.ca for admission in Fall 2026! Get in touch if you're interested in how brain circuits implement distributed computation, including dopamine-based distributed RL and probabilistic representations.
If you are at #SfN2025, don't miss Huihui's poster tomorrow (Sunday) morning at MM6 (PSTR095.13)! He has developed methods for barcoded connectomics across many vertebrates, from frogs to NHPs, and is comparing the single-cell anatomy of the song systems of zebra finches and parrots!
Annoyed at how difficult MAPseq dissections can be? Check out the new preprint from Kebschull undergrad Rishi Koneru and grad student @mmganant.bsky.social: www.biorxiv.org/content/10.1...
DART: A GUI Pipeline for Aligning Histological Brain Sections to 3D Atlases and Automating Laser Microdissection
The precise dissection of anatomically defined brain regions is the basis of many workflows in neurobiology. Traditionally, brain regions of interest are defined by visual inspection of tissue section...
biorxiv.org
Want to learn everything there is to know about barcoded connectomics, brain clearing, and modern neuroanatomy? There is still time to apply for the CSHL High Throughput Neuroanatomy course! Stipends are available. meetings.cshl.edu/courses.aspx...
Next-generation of barcoded projection mapping techniques: MAPseq2 and POINTseq! Congratulations @justuskebschull.bsky.social and team.
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.
Excited to share the first 2(!) preprints from the Kebschull Lab. The amazing @hyopilkim.bsky.social developed MAPseq2 & POINTseq and used them to map the dopaminergic cells of VTA and SNc. tl;dr MAPseq2=10x cheaper, 4x better; POINTseq=easy cell type specific barcoding; DA neurons=very cool.
Our work with Pablo Tano, @hyunggoo-kim.bsky.social Athar Malik, Alexandre Pouget and @naoshigeuchida.bsky.social exploring how dopamine neurons could enable multi-timescale reinforcement learning in the brain is out in @nature.com www.nature.com/articles/s41...
Multi-timescale reinforcement learning in the brain - Nature
Individual dopaminergic neurons encode future rewards over distinct temporal horizons.
nature.com
Thank you to @xinjin.bsky.social and @justuskebschull.bsky.social for presenting their research at the recent Klingenstein Fellowship Awards in Neuroscience Conference. 📷 : SimonProPhoto
Fantastic opportunity to move to Europe, and yes, it includes the UK! But applicants can be from any nationality. Our team at UCL is still growing. Get in touch if any of our work sounds interesting. delaslab.com
Delas Lab
at University College London. Decoding cis regulatory control during development.
delaslab.com
Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF
Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence
On Friday, Feb 14 ❤️, we will welcome Prof Justus Kebschull @justuskebschull.bsky.social of Johns Hopkins Biomedical Engineering for his talk on “Understanding brain function and evolution with barcodes and sequencing”. Happening at 11am in RW432. See you there!
This is the end of science as we know it if it stands—15% IDCs for all NIH Grants. grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
Postdoc (Baltimore, United States) Viral Phylodynamics & Neuroscience with @justuskebschull.bsky.social @rezakalhor.bsky.social More details: http://iddjobs.org/jobs/johns-hopkins-postdoc-position-in-viral-phylodynamics-neuroscience
Bioinformatician (Baltimore, United States) Viral Phylodynamics & Neuroscience with @justuskebschull.bsky.social @rezakalhor.bsky.social More details: http://iddjobs.org/jobs/hopkins-bioinformatician-position-in-viral-phylodynamics-neuroscience
Many academics point to bioRxiv as “the one thing improving science publishing”. If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2
Hopkins is recruiting 30 Bloomberg Distinguished Professors in AI + X (X = astrophysics, cancer, neuroscience, genomics, social sciences, etc.) hub.jhu.edu/2024/12/17/d... 22 of these 30 will be organized in clusters that were selected after rigorous external review. The list of clusters is:
Experience in viral phylodynamics? Check out this awesome opportunity to use those tools to understand brain structure 🧠🦠. We'll be next door neighbors and you can join the amazing infectious disease dynamics and neuroscience communities at Johns Hopkins
The Kebschull and @rezakalhor.bsky.social labs are recruiting a joint postdoc for an exciting project at the interface of phylodynamics and neuroscience. Come join us at JHU BME. Spread the word, and contact us if you are interested. #hiring 🧪🧠. More on www.kebschull-lab.org and below.
We are still looking to recruit a postdoc on (what I think) is a most exciting project!
The Kebschull and @rezakalhor.bsky.social labs are recruiting a joint postdoc for an exciting project at the interface of phylodynamics and neuroscience. Come join us at JHU BME. Spread the word, and contact us if you are interested. #hiring 🧪🧠. More on www.kebschull-lab.org and below.
The Kebschull and @rezakalhor.bsky.social labs are recruiting a joint postdoc for an exciting project at the interface of phylodynamics and neuroscience. Come join us at JHU BME. Spread the word, and contact us if you are interested. #hiring 🧪🧠. More on www.kebschull-lab.org and below.
Hello there! We are the Kebschull lab at Johns Hopkins University and love brains, barcodes, viruses, and sequencing. We develop new technology and work on a zoo of animals to understand how brains change over evolution and an animal's lifetime. Check out our lab at www.kebschull-lab.org 🧠🧪