Rick Huganir
@rhuganir.bsky.social
I am a neuroscientist at Johns hopkins University interested in the molecular mechanisms underlying learning and memory in health and disease.
The winner of OneNeuro's March #FotoFriday #FluorescenceFriday contest is "Unleash our inner programmers, without AI" submitted by @takualiu.bsky.social in the Marina Bedny Lab @jhuartssciences.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
Blast from the past: Hopkins relay team w @rhuganir.bsky.social @jasonsynaptic.bsky.social Gavin Rumbaugh
Finally, I’m deeply grateful to my PhD mentor @rhuganir.bsky.social and my postdoc mentor Jun Ding, as well as all the Huganir and Ding lab members, for many years of great scientific exchange, support, and friendship. Excited to continue this journey in beautiful Toronto! /3
Figure skaters can spin at 300+ times per minute without getting dizzy. Johns Hopkins scientists explain the brain science behind Olympic winter athletes' remarkable abilities. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2026/02/10/t...
Computer-based cognitive speed training linked to 25% reduced dementia risk up to 20 years later in NIH-funded study, offering hope for non-drug interventions. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2026/02/17/c...
The winner of OneNeuro's February #FotoFriday #FluorescenceFriday contest is "Spatial transcriptomics captures brain regions in the hummingbird bobtail squid" submitted by Alyson Hally in the @loyalgoff.bsky.social Lab at @hopkinsmedicine.bsky.social View BRAINART gallery: www.oneneurojhu.org/art/
"I worry about how poorly science is communicated to the public. There's a huge disconnect, and I think scientists need to do more to humanize what we do and make it accessible." — Blake Creighton, PhD Candidate www.oneneurojhu.org/2026/03/23/o...
"δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice" www.ibroneuroscience.org/article/S030...
δ-catenin haploinsufficiency is sufficient to alter behaviors and glutamatergic synapses in mice
At PSD, the N-cadherin-δ-catenin-ABP/GRIP complex functions as an anchor for GluA2. Heterozygous δ-catenin KO and G34S mice show impairments in social behavior and fear learning and memory. Only KO ha...
ibroneuroscience.org
The winner of OneNeuro's January #FotoFriday #FluorescenceFriday contest is "Electrophysiology of Cultured Neurons" submitted by Madison Yorkowski in the Ali Fatemi Lab at Kennedy Krieger Institute. View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
New Neuroscience Masters Degree at Johns Hopkins The M.S. degree in Neuroscience is a full-time in-person program consisting of intensive coursework followed by 12 months of laboratory research. The application deadline is May 15, and more information is available at neuroscience.jhu.edu/graduate/51
"Choose your training environment carefully. Lab culture and institutional culture will significantly impact your happiness and success, so choose carefully." - OneNeuro Profile: Seth Blackshaw, PhD @sethblackshaw.bsky.social www.oneneurojhu.org/2026/01/29/o...
Johns Hopkins scientists discover that brain cells constantly attempt to produce myelin at a steady pace throughout the brain, offering new insights for treating multiple sclerosis. @jhu.edu www.oneneurojhu.org/...
"We study human vision, focusing on the neural and computational basis of high-level vision using cognitive and computational neuroscience techniques." — Mick Bonner , PhD @mickbonner.bsky.social www.oneneurojhu.org/2026/01/21/o...
Study section done. Now can enjoy the PC learning and memory meeting! Looking forward to some stimulating science chats on the ski lift as well this weekend.
Rescue of excitotoxicity in a mouse model of a rare neurodevelopmental disorder by ASO treatment.
Rick Huganir@rhuganir.bsky.social · 7mo agoWe just posted our new paper, “Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant”. In this paper, we, in collaboration with Shu-Ling Chiu's lab, generated a mouse model of a rare missense mutation in the AMPA receptor GluA1 subunit. www.biorxiv.org/content/10.6...
We just posted our new paper, “Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant”. In this paper, we, in collaboration with Shu-Ling Chiu's lab, generated a mouse model of a rare missense mutation in the AMPA receptor GluA1 subunit. www.biorxiv.org/content/10.6...
Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant
AMPA receptors (AMPARs) mediate fast excitatory synaptic transmission and are essential for neuronal development and brain function. We investigated the role of a recurrent variant in the AMPAR GluA1 ...
biorxiv.org
The winner of OneNeuro's November #FotoFriday #FluorescenceFriday contest is "Portrait of a Claustrocortical Neuron" submitted by Baldomero B. Ramírez Cantú in the Solange Brown Lab at @hopkinsmedicine.bsky.social View the complete gallery of OneNeuro BRAINART images here: www.oneneurojhu.org/art/
The winner of OneNeuro's October #FotoFriday #FluorescenceFriday contest is "Purkinje cell complex spikes & simple spikes," submitted by Chenhao Bao in the Cullen lab at JHU Biomedical Engineering. @thecullenlab.bsky.social @chenhaobao.bsky.social Complete gallery: www.oneneurojhu.org/art/
Johns Hopkins scientists discover how brain cells form nanotube networks to transport toxic molecules like amyloid-beta between neurons, offering new insights into Alzheimer's disease progression. @hyungbaekwon.bsky.social @hopkinsmedicine.bsky.social @science.org www.oneneurojhu.org/2025/11/06/n...
Four @jhu.edu @jhuartssciences.bsky.social faculty members were recently named part of three large-scale, multi-institutional, highly competitive collaborations funded by the @simonsfoundation.org to explore novel areas in established fields. www.oneneurojhu.org/2025/09/23/f...
New test detects brain cancers in cerebrospinal fluid with 80% sensitivity and 100% specificity, enabling clinicians to better detect cancer and better understand the disease status, supporting a more tailored approach to patient care. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/06/t...
The winner of OneNeuro's September #FotoFriday #FluorescenceFriday contest is "The Cochlear Constellation," submitted by Yassine Balhi in Amanda Lauer's lab at @hopkinsmedicine.bsky.social. View the complete gallery here: www.oneneurojhu.org/art/
Novel in utero gene therapy shows promise for spinal muscular atrophy, with potential to help babies reach motor milestones previously thought impossible. @hopkinsmedicine.bsky.social www.oneneurojhu.org/2025/10/15/n...
I am excited to announce that the Johns Hopkins University Solomon H. Snyder Department has become an interdivisional department between the School of Medicine and the Krieger School of Arts and Sciences, unifying neuroscience research and education across the university. hub.jhu.edu/2025/09/15/j...
OneNeuro's August #FotoFriday #FluorescenceFriday contest winner is "Cellular Subtype Composition of an Amphetamine-activated Ensemble in mPFC," by Suhaas Adiraju from @martinowk.bsky.social at the @lieberinstitute.bsky.social View the complete gallery here: www.oneneurojhu.org/art/
The statement by Caroline Kennedy about RFK Jr has aged well www.youtube.com/shorts/fm0-a...
Caroline Kennedy calls cousin RFK Jr a 'predator' | ABC NEWS
YouTube video by ABC News (Australia)
youtube.com
Johns Hopkins scientists discover how a protein organizes message-carrying "bubbles" in brain synapses—advancing understanding of memory formation and learning. www.oneneurojhu.org/... @watanabelab.bsky.social
A giant in the field! Gave some of the best talks I have ever seen.
Piali Sengupta@senguptalab.bsky.social · 12mo agoA legend. Was and am still inspired by his work. Sad to hear this.
A legend. Was and am still inspired by his work. Sad to hear this.
The Rockefeller University @rockefeller.edu · 12mo agoWe are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery.
