#Parasitology #Malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission @jvr-lab.bsky.social http://dlvr.it/TQTlT1
Joel Vega-Rodriguez
@jvr-lab.bsky.social
Malaria and mosquito scientist at the Laboratory of Malaria and Vector Research, NIAID, NIH. 🇵🇷🏳️🌈🦟🔬🧑🏽🔬🏐🏋🏽
#Parasitology #Malaria parasite invasion damages mosquito salivary glands, alters saliva protein composition, and attracts immune cells, potentially increasing parasite transmission @jvr-lab.bsky.social http://dlvr.it/TQNwSG
Postdoc opportunity ALERT! Interested in exploring interactions between #wolbachia , #anopheles mosquitoes and #microbiome? check this postdoc position in Dr. Grant Hughes lab at Liverpool School of Tropical Medicine @mosquitomicrobe.bsky.social app.vacancy-filler.co.uk/salescrm/Car...
Post Doctoral Research Associate in Wolbachia Biology | Liverpool School of Tropical Medicine
Ready to make a difference in vector biology research? We are looking for a dedicated and enthusiastic researcher to join an exciting BBSRC-funded project exploring the fascinating interactions betwee...
app.vacancy-filler.co.uk
Enjoying a beer with my friend Gabi in a beautiful Aachen afternoon. It was great to see you. Thank you for the invitation and the great time. 👩🏼🔬🧑🏽🔬 🦠 🦟 🔬 🧬 @gabrielepradel.bsky.social
Exited to deliver the keynote address together with Markus Ganter at the @spp2225.bsky.social EXIT Workshop in beautiful Aachen, Germany. Thank you @gabrielepradel.bsky.social for the invitation and hospitality. 👨🏽🔬 🦟 🦠 🩸🔬 @rwth.bsky.social @dfg.de @niaidnews.bsky.social
Gabriele Pradel@gabrielepradel.bsky.social · last yr.The @spp2225.bsky.social EXIT-Workshop @dfg.de @rwth.bsky.social in Aachen was a big success. I thank our keynote speakers Markus Ganter and Joel Vega-Rodriguez for the exciting talks!
🚨 New preprint alert! 🚨 We’ve uncovered a key player in malaria parasite cell division—meet PfAnchor, the first apicoplast-specific dynamin adaptor protein! Check the thread below 🧵for more details. #U_ExM #Malaria #Apicoplast www.biorxiv.org/content/10.1...
An Essential Adaptor for Apicoplast Fission and Inheritance in Malaria Parasites
Blood-stage Plasmodium falciparum parasites rely on a non-photosynthetic plastid, the apicoplast, for survival, making it an attractive target for antimalarial intervention. Like the mitochondrion, th...
biorxiv.org
Pre-print Alert! We uncover new sporozoite biology in mosquitoes, classified sporogony stages in oocysts and showed that sporozoites produce 2 rhoptry pairs, each one specialized for salivary gland and hepatocyte invasion. @benliffner.bsky.social @sabsalon.bsky.social @thiagoluizsilva.bsky.social
Ben Liffner@benliffner.bsky.social · last yr.Our study looking at sporozoite development and salivary gland invasion using expansion microscopy is now up as a pre-print! A little thread below about this interesting study that was born out of a seminar 🧵 @sabsalon.bsky.social @jvr-lab.bsky.social www.biorxiv.org/content/10.1...
📢 @lstmnews.bsky.social : "Drug used for rare genetic disorders kills #mosquitoes capable of #malaria transmission" 🦟 www.lstmed.ac.uk/news-events/...
Drug used for rare genetic disorders kills mosquitoes capable of malaria transmission
Nitisinone, a medication already used to treat rare genetic disorders like tyrosinemia type 1, blocks an essential enzyme mosquitoes need to digest their blood meal, resulting in rapid death.The new
lstmed.ac.uk
Look at those beautiful #mosquito midguts infected with #malaria parasites. Congratulations @sabsalon.bsky.social and @benliffner.bsky.social
Sabrina Absalon, Phd@sabsalon.bsky.social · last yr.Ten years of bigger samples, better views mcgovern.mit.edu/2025/03/03/t... Thank you for including our lab's contribution in your remarkable piece about what I believe is the most revolutionary method for studying tiny, fascinating apicomplexans. @benliffner.bsky.social @jvr-lab.bsky.social
Congratulations @benliffner.bsky.social. #U_ExM #Malaria revolutionized studying the cell biology of Apicomplexan parasites, and I love the work we did together ;-)
New review alert-Mosquito saliva does more than just help them feed—it also influences blood responses in the midgut, enhancing Plasmodium transmission. Could targeting saliva proteins be the key to blocking disease spread? #Malaria #Mosquito #VectorControl www.sciencedirect.com/science/arti...
Our 2025 March issue bit.ly/2N9R8Es reviews blood impact on vector-borne diseases, zoonotic Giardia transmission in cattle, parasite subcellular dynamics, Bacillus thuringiensis for nematode management, heptalaminate membrane of intravascular schistosomes, trade-offs in virulence evolution, & more
New Pre-print from our lab High-Resolution Proteomics Unveils Salivary Gland Disruption and Saliva-Hemolymph Protein Exchange in Plasmodium-Infected Mosquitoes Led by @thiagoluizsilva.bsky.social 🦟 🦟🦟🦟🦟🦟🦟🦟🦟🦟🦟 #mosquito #malaria #proteomics #infectiousdiseases www.biorxiv.org/content/10.1...
High-Resolution Proteomics Unveils Salivary Gland Disruption and Saliva-Hemolymph Protein Exchange in Plasmodium-Infected Mosquitoes
Plasmodium sporozoites, the stage that initiates a malaria infection, must invade the mosquito salivary glands (SGs) before transmitting to a vertebrate host. However, the effects of sporozoite invasi...
biorxiv.org
New paper published with the Benoit lab at the University of Cincinnati! www.sciencedirect.com/science/arti...
Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods
Dry conditions increase blood feeding in mosquitoes, but it is unknown if dehydration-induced bloodmeals are increased beyond what is necessary for re…
sciencedirect.com
Check out our paper, co-authored by @akhorramnejad.bsky.social and me. Published in @commsbio.bsky.social We explore how global change will affect mosquito-virus interaction. We use single or multi-generational exposure to heat to address this. A 🧵 with our results (1/5) rdcu.be/d8wse
rdcu.be
New preprint from the lab in which we show that Trichoderma culture supernatant kills Aedes albopictus larvae 🦟🍄 www.biorxiv.org/content/10.1...
Larvicidal activity of Trichoderma atroviride (Hypocreales: Hypocreaceae) against Aedes albopictus (Diptera: Culicidae)
Larviciding is an important part of effective integrated mosquito management. However, growing resistance to chemical and bacterial-based insecticides requires biocontrol agents with novel modes of ac...
biorxiv.org
Our article on #mosquito salivary apyrase featured at The Scientist Thanks Mary Ann McDowell for the insightful comments! “Targeting Mosquito Spit Could Stop Parasites in Their Tracks” www.the-scientist.com/targeting-mo...
Targeting Mosquito Spit Could Stop Parasites in Their Tracks
A protein found in the saliva of Anopheles gambiae stopped blood from clotting in the insects’ stomachs and aided parasite transmission.
the-scientist.com
Our paper on the role of #mosquito salivary apyrase in regulating blood meal #hemostasis and #malaria #parasite transmission. Apyrase #immunization inhibits both transmissions. www.nature.com/articles/s41...
Mosquito salivary apyrase regulates blood meal hemostasis and facilitates malaria parasite transmission - Nature Communications
Here, Pala et al. show that mosquito salivary apyrase regulates hemostasis in the mosquito blood meal, boosting malaria transmission. They demonstrate that immunizing against apyrase inhibits parasite...
nature.com
Our paper on U-ExM for mosquito tissues (MoTissU-ExM) in BMC methods! Great collaboration with @sabsalon.bsky.social and @benliffner.bsky.social bmcmethods.biomedcentral.com/articles/10....
Mosquito Tissue Ultrastructure-Expansion Microscopy (MoTissU-ExM) enables ultrastructural and anatomical analysis of malaria parasites and their mosquito - BMC Methods
Background Study of malaria parasite cell biology is challenged by their small size, which can make visualisation of individual organelles difficult or impossible using conventional light microscopy. ...
bmcmethods.biomedcentral.com