We’re collaborating with Lausanne University Hospital (CHUV) to advance diagnostic applications of single-cell and spatial technologies for cancer care, using Chromium Flex Apex and Xenium (later: Atera) to identify biomarkers that may support future diagnostics: https://bit.ly/4bjtC64
Now available as a publication! Subcellular resolution with Visium HD. www.nature.com/articles/s41...
Subcellular mRNA localization patterns across tissues resolved with spatial transcriptomics - Nature Communications
Subcellular RNA localization plays a central role in post-transcriptional regulation. Using high-resolution spatial transcriptomics and a computational approach, the study maps intracellular mRNA loca...
nature.com
@shalevitzkovitz.bsky.social · 11mo agoHiVis also enables automated nucleus and cytoplasmic segmentation from H&E images, facilitating extraction of nuclear-cytoplasmic localization.
Maximize the discovery power of your toolkit and the impact of your preclinical research with new rat probe sets, enabling #SingleCell and #Spatial analysis of #FFPE tissues with #Flex Apex and #VisiumHD. Learn more here: https://bit.ly/4dSs9UK
Big news for multiomics: GEM-X technology has arrived for the @10xgenomics.bsky.social Multiome kit. 🧬 Expect to double the cells, superior sensitivity, and a more reliable workflow—supported by an upgraded nuclei isolation kit. Catch the deep dive in our upcoming webinar: 🔗 bit.ly/429MQWK
10x Genomics
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On Wednesday, April 29, the Atera 10x Genomics World Tour arrives in Belgium! > Whole Transcriptome Analysis > Massive Throughput > Single-Cell Sensitivity All in a new subcellular-resolution spatial platform: Atera Be in the front seat of spatial biology, register today: bit.ly/4su0Ypn
10x Genomics Atera World Tour 2026 | Leuven
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Studying biology has long meant working with fragmented tools. With Atera, for the first time ever, biology can be measured as a complete system in its native context, at scale, removing the constraints that have held spatial biology back: https://bit.ly/48bYvYF
1/ Philipp Mallm from the @dkfz.bsky.social Single-cell Open Lab just broke the news at #AACR26: the first results on colorectal cancer (CRC) tissue analysis with the new Atera spatial transcriptomics platform from @10xgenomics.bsky.social. Is it "making the impossible possible?" 🧵
Last night we unveiled the impossible. Now we invite you to check out Atera for yourself at booth #3217! Or, if you're not at #AACR26, register for one of our webinars starting 4/21 to get a deeper look into the future of #spatialbiology: https://bit.ly/4b5SnBx
While there is a lot of momentum in spatial transcriptomics, Atera brings true acceleration. Excited to see how Atera will increase our understanding of biology and help improve human health. Let me know if you want to talk.
10x Genomics@10xgenomics.bsky.social · 4mo agoThe impossible is finally here: introducing Atera, uncompromised #spatialbiology that lets you analyze up to 800 1 cm2 whole transcriptome samples/year with #singlecell sensitivity. Impossible breakthroughs await: register now for an in-depth look at our 4/21 webinar. https://bit.ly/4b5SnBx
Capturing somatic mutations in single-cell probe-based assays (ie. 10X Flex) is a hard task, especially if you don't know *exactly* the mutations you want to capture, or if your target sequence is a mutational hotspot with many possible alternative alleles. Here's the way we pulled this off. Enjoy!
Luciano Martelotto@lgmartelotto.bsky.social · 4mo agoWe GoT a Filling…uuuuhoooo 𝗧𝗮𝗿𝗴𝗲𝘁𝗲𝗱 𝘀𝗲𝗾𝘂𝗲𝗻𝗰𝗶𝗻𝗴 𝗼𝗳 𝗺𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 𝘃𝗶𝗮 𝗥𝗡𝗔-𝘁𝗲𝗺𝗽𝗹𝗮𝘁𝗲𝗱 𝗴𝗮𝗽 𝗳𝗶𝗹𝗹𝗶𝗻𝗴 𝗼𝗳 𝗼𝗹𝗶𝗴𝗼𝗻𝘂𝗰𝗹𝗲𝗼𝘁𝗶𝗱𝗲𝘀 𝗳𝗼𝗿 𝘀𝗶𝗻𝗴𝗹𝗲-𝗰𝗲𝗹𝗹 𝗥𝗡𝗔-𝘀𝗲𝗾 www.biorxiv.org/content/10.6...
Join us in Leuven to see the (im)possible with your own eyes! Register here, limited seats available: pages.10xgenomics.com/ugm-2026-04-...
10x Genomics World Tour 2026 | Leuven
pages.10xgenomics.com
The impossible arrives in just two short weeks: where will you be when it does? oin us for our webinar on 4.21 and witness the start of impossible breakthroughs: https://bit.ly/4sm2KrX #10xGenomics
Join us in Leuven to see the (im)possible with your own eyes! Register here, limited seats available: pages.10xgenomics.com/ugm-2026-04-...
10x Genomics World Tour 2026 | Leuven
pages.10xgenomics.com
Spatial Gut-Microbiome MegaTranscriptomics Use in situ polyadenylation on #Visium #StereoSeq to enhance host & bacterial RNA recovery (⏫99-fold) Fresh-frozen🐭GI Non-coding RNAs enriched to gut wall Microorganisms enriched at CRC tumor boundary #NatMicrobiol 2026 www.nature.com/articles/s41...
Exciting news! Our Epi Multiome assay is getting the GEM-X performance upgrade with incredible benefits across the entire workflow, from more reliable sample prep to higher gene sensitivity and more. Pre-order today > https://bit.ly/4sZwefD
Every sample has a story. And it could change someone's life. Uncover the biology behind treatment success or failure by profiling FFPE and fixed whole blood samples. Learn how single cell and spatial are revolutionizing biomarker research in cancer, immunology, and neuroscience. bit.ly/40RqhFr
Welcome to the first edition of #SampleSpotlight! Every week, we’ll highlight a different sample type that works seamlessly with the Flex Apex assay. This week’s spotlight: FFPE tissue. Every sample has a story. Tell them with Flex Apex. Find out more: https://10xgen.com/1WD
From #PCR, to #NGS, to #scRNAseq, yesterday’s pipe dream is today’s standard. Science follows a pattern, after all: first, something’s impossible. Then, it’s indispensable. So what’s next on that list? Join us for a webinar this April to find out. https://bit.ly/4tJv9tD
Science, at its core, is about breakthroughs: discovering new methods, finding new answers, and figuring out that the impossible...isn’t. So what will you do when you can achieve the impossible? https://bit.ly/4rZJ5Ot
What if you could simply ask your analysis tools for answers? We’re collaborating with Anthropic to make that happen, working to turn #singlecell & #spatial analysis into a natural conversation, not a coding lesson. Learn more > https://bit.ly/4nkyURZ
Another independent benchmarking study, this time on neutrophils. Comparing 10X 3 prime, 10X Flex, Parse Evercode and Hive. www.cell.com/cell-reports...
Comparison of single-cell RNA-seq methods to enable transcriptome profiling of neutrophils in clinical samples
Hatje et al. evaluate current fixed single-cell technologies to determine their suitability for measuring the neutrophil transcriptome and their potential for implementation in clinical trials.
cell.com
1/ First preprint from @jdemeul.bsky.social lab 🥳! We present our new multi-modal single-cell long-read method SPLONGGET (Single-cell Profiling of LONG-read Genome, Epigenome, and Transcriptome)! www.biorxiv.org/content/10.1...
Imagine detecting bone marrow disorders without a painful aspiration! The PERIBLOOD clinical trial by CLISEQ Ltd., the Weizmann Institute of Science & Weizmann’s commercial arm Yeda will see if a blood draw & GEM-X #scRNAseq could help develop future diagnostics. https://bit.ly/46i7TrX
✨ Join us on August 28 for an educational webinar that covers the #Xenium workflow, including new features of the platform and expert tips and tricks 🔬 Learn more and reserve your spot here: bit.ly/3U2D5FT
Yes, you can use @10xgenomics.bsky.social Xenium high resolution transcriptomics on plants. Jhu et al. wrote a "how-to-guide" with specific protocol modifications. Medicago truncatula roots and nodules FFPE tissue, 480 genes. Check it out here: www.biorxiv.org/content/10.1...
Plant-Compatible Xenium In Situ Sequencing: Optimised Protocol for Spatial Transcriptomics in Medicago truncatula Roots and Nodules
Elucidating the spatial and temporal regulation of gene expression during plant organogenesis is crucial for enabling precise crop improvement strategies that incorporate beneficial traits into crops ...
biorxiv.org
New preprint by M4I, Maastricht, The Netherlands integrating high-resolution MALDI-MSI with Xenium single cell spatial transcriptomics on one single tissue section. www.biorxiv.org/content/10.1...
One Section, Two Worlds: Single-Cell Integration of MALDI-MSI and Spatial Transcriptomics on the Same Single Tissue Section
Understanding tissue complexity requires spatially resolved multiomic data at single-cell resolution. Here, we present a workflow that integrates high-resolution matrix-assisted laser desorption ioniz...
biorxiv.org
Want to learn more about high resolution, high plex spatial transcriptomics? New 10X Genomics Xenium educational webinar on Thursday Aug 28, 2025 ⋅ 15:00 – 16:00 (Central European Time - Brussels). Register here: bit.ly/4fjtYKM
10x Genomics
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New on Xenium: validated & ready-to-use protein panels! Now you can analyze 27 proteins alongside #spatial RNA for multiomic insights into #cancer, #immunology & more. Get a hands-on look with our interactive dataset & then pre-order your assay: bit.ly/4o0896R
