Bi, D., Lopez, J. H., Schwarz, J. M., & Manning, M. L. (2014). Energy barriers and cell migration in densely packed tissues. Soft matter, 10(12), 1885-1890. #EpithelialMechanics buff.ly/evpRhvC
Ruppel, A., Misiak, V., Arzash, S., Selma-Herrador, D., Boudou, T., ... & Balland, M. (2026). A minimal in vitro assay for cell intercalation highlights the importance of interfacial tension and migratory forces. Nature Physics, 1-14. #EpithelialMechanics buff.ly/T5ZnvnR
The evolving resolution of islet ultra structure @diabetologiajnl.bsky.social link.springer.com/article/10.1...
Islet ultrastructure: past achievements and future directions - Diabetologia
Islets of Langerhans constitute the endocrine component of the pancreas and comprise the main cell types responsible for the regulation of glucose homeostasis. Beta cells produce and secrete insulin, ...
link.springer.com
A must-read for #SpatialTranscriptomics cell type deconvolution methods👹 5 large categories, 67 methods!🤠 Regression Dimensionality reduction Bayesian Optimal transport Deep learning #NatureRevGenet 2025 www.nature.com/articles/s41...
#BloodBrainBarrier #Proteomics A reference protein atlas of the adult mouse brain vasculature 1⃣Proteomic ruler technique & 2⃣Deconvolution with parallel bulk proteomics & scRNAseq▶️ Protein copy numbers of 9940 proteins in 8 Neurovascular cell types #PNAS 2026 www.pnas.org/doi/10.1073/...
Combination S100A1 and ARC gene therapy as a treatment for DMD cardiomyopathy: doi.org/10.1172/jci....
JCI Insight - Combination S100A1 and ARC gene therapy as a treatment for DMD cardiomyopathy
ResearchIn-Press PreviewCardiologyMuscle biology Open Access | 10.1172/jci.insight.204852
doi.org
1/7 On August 12, 2026 a total solar eclipse will take place. Its path of totality will cross northern Russia, the Arctic, Greenland, western Iceland, the Atlantic Ocean, northern Spain and a small corner of Portugal. Maximum duration of totality: 2 min 18 s. 🔭⚛️🧪 #TotalSolarEclipse #science
Rhoptry biogenesis in #Plasmodium sporozoites is uncoupled from #mitosis and forms distinct pairs. New study from Benjamin Liffner (Adelaide University), Sabrina Absalon @sabsalon.bsky.social (Indiana University) and colleagues: rupress.org/jcb/article/... #Organelles #CelDivision #Malaria
Richa, P., Häring, M., Wang, Q., Choudhury, A. R., Göpfert, M. C., Wolf, F., Großhans, J., & Kong, D. (2025). Synchronization in epithelial tissue morphogenesis. Current Biology, 35(11), 2495–2508.e4. doi.org/10.1016/j.cu... #EpithelialMechanics
Perez-Tirado, A., Unkelbach, U., Oswald, T. A., Rheinlaender, J., ... Honigmann, A., & Janshoff, A. (2025). Differences in apical and basal mechanics regulate compliance of curved epithelia. Cell Reports Physical Science, 6(3), 102485. doi.org/10.1016/j.xc... #EpithelialMechanics
Maupérin, M., Sun, Y., Glandorf, T., Oswald, T. A., ... Yan, J., & Citi, S. (2025). A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls tight junction and apical cortex mechanics. Nature Communications, 16(1), 2514. www.nature.com/articles/s41... #EpithelialMechanics
Finger, A.-M., Hendley, A. M., Figueroa, D., Gonzalez, H., & Weaver, V. M. (2025). Tissue mechanics in tumor heterogeneity and aggression. Trends in Cancer, 11(8), 806–824. doi.org/10.1016/j.tr... #EpithelialMechanicsReview
Bertet, C., Sulak, L., & Lecuit, T. (2004). Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation. Nature, 429(6992), 667–671. #EpithelialMechanics doi.org/10.1038/natu...
MuSiC2 MUlti-Subject SIngle Cell deconvolution github.com/xuranw/MuSiC Account for cell type-specific differential expression among subject (& experimental/disease) conditions More weights on genes with low cross-subject variance #BriefBioinform 2022 academic.oup.com/bib/article/...
Drug2Cell github.com/Teichlab/dru... Drug target discovery using single-cell/-nucleus transcriptomics data Parse ChEMBL database (>24 M bioactivity records) into drugs & their targets Per-cell scoring + Marker enrichment @teichlab.bsky.social #Nature 2023 www.nature.com/articles/s41...
1/8 This is the Sun's surface, the photosphere, seen as we've NEVER seen it before. 🔭 The Hawaiian Islands give you a scale. Those thin filaments? They're magnetic boundaries shaped by the Kelvin-Helmholtz instability (KHI) previously ONLY theorized, and FINALLY observed.⚛️🧪 #stellarastro #Sun
Single-cell transcriptomics of 👤Juvenile Nasopharyngeal Angiofibroma 2 tumors +tumor-adjacent mucosa +healthy ethmoid sinuses 5 major tumor cell types Neural crest-like cells >75%➡️least DEGs😮 vs mucosa Endothelial cell➡️most DEGs pericyte fibroblast SMC medRxiv 2026 www.medrxiv.org/content/10.6...
Antigen presentation at the blood–brain barrier amplifies neuroinflammation | @cp-trendsimmuno.bsky.social www.cell.com/trends/immun...
Antigen presentation at the blood–brain barrier amplifies neuroinflammation
Immune surveillance of the central nervous system (CNS) is regulated by the brain barriers. Antigen presentation at the blood–brain barrier (BBB) has been proposed to promote antigen-specific T-cell e...
cell.com
👀 - me watching project channels on Slack on Fridays for #FluorescenceFriday contributions... literally fresh off the scope from JHU undergrad Mahima Sanghera, @ishbeldelrosario.bsky.social and @svitlanabach.bsky.social some dorsal raphe in human 🧠 labeling 5HT neurons - 🟣TPH2 and 🟡 SLC6A4
One more from mouse 🧠 for #FluorescenceFriday because I AM IN LOVE with that green neuron up top. These are virally labeled projection neurons in prelimbic cortex headed to either the locus coeruleus or the ventral tegmental area. Brought to you by RA Daniel Olivares and the LIBD circuits team.
Hot take but any reporter that makes the actin network visible will make any cell look awesome under the microscope! These Xenopus 🐸 ectoderm cells are expressing an actin tension sensor, and you can see the retrograde flow very nicely. Actin is better than microtubules 😁 #FluorescenceFriday
#MetaplasticBreastCancer #CaseReport 65 y/o Recurrent left breast mass (4 yr after initial invasive TN carcinoma + lumpectomy) 4.5 x 3 x 3 cm TN Osteoblast marker SATB2+ Osteosarcomatous differentiation Lymph node- #FrontOncol 2026 www.frontiersin.org/journals/onc...
A key resource and community gathering spot for #zebrafish reseachers and affiliates! Big thx to the team running the Slack space for all of us. #ZebrafishRock #zerbafish #ShareYourResearch #ShareYourTools
Zebrafish Rock!@zebrafishrock.bsky.social · 6d agoNow you can share fishy news, jobs and research with the Zebrafish Rock! network without a social media account! Get direct access to the #zebrafish community and beyond by filling out the Google Forms at our website 😊 #RockOn 🧪
#Mechanobiology #Hypertension Bulk transcriptomes & secretomes of 👤aortic smooth muscle cell Hydrostatic pressure 180/120 mmHg, 1 Hz 120/60 mmHg, 1 Hz vs Cyclic stretch 10% strain, 1 Hz vs static Hypertensive pressure ⬆️HHIP, Netrin4, HGF #JPhysiolSci 2026 www.sciencedirect.com/science/arti...
Proof of the 40-year old Bandelt-Dress conjecture on the maximum quartet distance between phylogenetic trees (and an interesting connection to independence testing). arxiv.org/abs/2608.03542
The maximum quartet distance between phylogenetic trees
The quartet distance counts the four-leaf subsets on which two binary phylogenetic trees display different topologies. We prove that its maximum over trees on $n$ leaves is $(2/3+o(1))\binom{n}{4}$, r...
arxiv.org
Andersen, B. H., Safara, F. M. R., Grudtsyna, V., Meacock, O. J., Andersen, S. G., Durham, W. M., Araujo, N. A. M., & Doostmohammadi, A. (2025). Evidence of universal conformal invariance in living biological matter. Nature Physics, 21(4), 618–623. www.nature.com/articles/s41... #EpithelialMechanics
The AJP-Lung editorial fellowship is inviting applications for a new round: ow.ly/rUAN50Zq10K I really enjoyed and benefitted from participating - more info in this article from previous fellows: doi.org/10.1152/ajplung.00251.2026
#Aging #HutchinsonGilfordProgeriaSyndrome Progressive Increase in Somatic Mutations in Progeroid Aortic Smooth Muscle Cells LmnaG609G/G609G🐭 6~12 wk SNV burdens (SComatic, MutationalPatterns) corr. ROS DNA damage ER stress p53 #GenomeMed 2026 link.springer.com/article/10.1...
#DBfeature #ICYMI Genetic knockout suggests Isl1 enhancer redundancy in mouse hindlimb development By Seth Olson, Yasuhiko Kawakami, et al. tinyurl.com/2jjje2sn
MYRF & Mesothelium Inducible 🐭inactivation of MYRF 👉Congenital Diaphragmatic Hernia (E6.5 KO) 👉Lung hypoplasia, earlier than herniation (E6.5/E12.5 KO) 👉Pleuroparenchymal Fibroelastosis-like phenotype (E12.5 KO) 👉Mesothelial thickening (P1 KO) #DevCell 2026 www.sciencedirect.com/science/arti...
