Excited to share this recent methods article! We detail the purification of tubulin from HeLa S3 cells but the method can be adapted for many other cultured cells or tissues. Many thanks to @mlpimm.bsky.social @xyzeke.bsky.social @thotta.bsky.social Yang Yue, and Puck Ohi

Cytoskeleton Journal@cytoskeljournal.bsky.social · 12mo ago

A fantastic #openaccess Techniques and Procedures paper from Kristen Verhey's lab is available in #CYTOSKELETON! Purification, Fluorescent Labeling, and Detyrosination of Mammalian #Cell #Tubulin for #Biochemical Assays. Check it out: onlinelibrary.wiley.com/doi/full/10.... @kjverhey1.bsky.social

I never thought watching microtubules break could be so interesting! I learned so much about mechanics and modeling in this work and am extremely grateful to Archie Geng for leading the way. Also huge thanks to François Nédélec for creating Cytosim and providing advice along the way.

Journal of Cell Biology@jcb.org · last yr.

Geng, @kjverhey1.bsky.social et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors rupress.org/jcb/article/...

Super excited about this work. We generated recombinant versions of the GT335 (anti-glutamylated tubulin) and 6-11B-1 (anti a-tubulin K40 acetylation) monoclonal antibodies. They work great!! Big boost for reproducibility and access to reagents. 😀🙌 onlinelibrary.wiley.com/doi/10.1002/...

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Post-translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology an....

onlinelibrary.wiley.com

Meet the 14 scientists named 2025 ASCB Fellows! Honored for excellence in research, mentorship, and service, they’ll be recognized at Cell Bio 2025 this December in Philadelphia. Read more: www.ascb.org/society-news...

Fourteen Visionary Scientists Named 2025 ASCB Fellows - ASCB

The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellows—a prestigious honor recognizing their exceptional contributions to cell...

ascb.org

Ever wonder how many lives have been saved by NIH-funded research - including your own? Enter any medical condition and instantly see how your tax dollars transformed science into survival. www.ourhealthroi.com

Our Health ROI

Explore how your tax dollars fund life‑saving medical research.

ourhealthroi.com

Stand Up For Science in Michigan. Great lineup of inspiring speakers across biology, environmental science, policy, medicine, etc. Hearing their words and seeing the participation of people from young to old gives me some needed hope!

Thankful for groups like this!

Education for All@education4all.bsky.social · 3y ago

Higher Education will continue to be a target of the anti-democratic, anti-DEI, anti-intellectual movement. Those concerned, follow and join @Ed4AllAboutAll--a group of #HigherEducation leaders seeking to collaborate about these issues. www.abcactionnews.com/news/state/f...

Ever wondered about how accessible the tubulin C-terminal tails (CTTs) are within the microtubule lattice? Takashi Hotta (Puck Ohi lab) will present our work at a poster Tuesday 1:30pm (P2401, B8) and in a talk Tuesday 6:15pm (room 30C). #cellbio24 #CellBio2024 #cytoskeleton

Attending ASCB/EMBO 2024? Interested in microtubule integrity, mechanical stress, condensates, and/or kinesins? Come to my poster Monday 1:30pm, P1699, B4. "Multi-kinesin complexes impart mechanical stress that results in microtubule fragmentation in cells" #cellbio24 #CellBio2024 #cytoskeleton

Future Faculty Workshop: Apply now for the next (May 2-5) session of NextProf if you are interested in a faculty career in science or mathematics and have a demonstrated commitment to diversity https://sites.lsa.umich.edu/nextprof-science/how-to-apply/

"We recognize how difficult it was for these eight women to come forward to share their experiences. We thank them for their courage and we apologize to each one of them and to all survivors."...

"We can do better. We will get better. We will be better together" by @DrRubidium in @PictureaSciFilm. If you believe we need to do better in fighting sexual and gender harassment at #UMich, sign the petition @ http://shorturl.at/hmtL5 #UMCourage

Kristen Verhey@kjverhey1.bsky.social · 6y ago

We support the survivors of Martin Philbert & Robert Anderson. We see their courage; now it’s our turn to be courageous. We challenge @UMich to make transformative change & be #LeadersandBest. Sign @ http://shorturl.at/hmtL5 #UMCourage #UMAgainstViolence #MeToo #MeTooPhD

We support the survivors of Martin Philbert & Robert Anderson. We see their courage; now it’s our turn to be courageous. We challenge @UMich to make transformative change & be #LeadersandBest. Sign @ http://shorturl.at/hmtL5 #UMCourage #UMAgainstViolence #MeToo #MeTooPhD

It's not rocket science... A powerful argument for wearing a mask, in visual form https://www.washingtonpost.com/business/2020/10/23/pandemic-data-chart-masks/?tid=ss_tw

just learned about UInclude - a web application that eliminates gender-biased language from job descriptions. It provides replacements for gendered words and gets the job description to a place of gender neutrality! http://www.uinclude.com/

Really enjoyed this historical perspective on plagues and how they have changed civilizations, from the Roman empire to the AIDS epidemic to what is to come from COVID-19 https://nymag.com/intelligencer/2020/07/coronavirus-pandemic-plagues-history.html

Breane Budaitis' last day in the lab 🥲 and she gave me this amazing painting of microtubules and motors. She is so talented in so many ways 🌟👏 I feel so lucky to have had the opportunity to work with her over the years 😀

Finally had a chance to read this excellent article about the accumulated disadvantages facing women in academia. In-depth, comprehensive, accessible. #WomeninSTEM #GenderEquality @500womensci https://nplusonemag.com/issue-34/essays/sexism-in-the-academy/ via @nplusonemag

Anyone attending #BPS20 in San Diego last month have trouble with @WestinGaslampSD charging them for rooms they didn't book? UG booked room then cancelled same day. They still charged us. And for a room they say he booked next day. We have no email. Waiting for them to provide it

Support a local treasure: Literati Bookstore https://www.gofundme.com/f/support-literati-bookstore-amp-booksellers?utm_source=twitter&utm_medium=social&utm_campaign=p_cp+share-sheet

Microtubules, motors, cilia, spindles, neurons... and more! Get your abstracts in for the EMBO/EMBL Microtubules 2020 meeting. Many talks are selected from the abstracts. Deadline March 9. Please RT!! @EMBO. @embl...

Committed to diversity in STEM? Looking for tips on getting academic jobs? Want feedback on your research & teaching statements? If you are a Postdoc or advanced PhD student, Apply by Jan. 26! @UMich #NextProfScience workshop May 4-7, 2020 Expenses paid. http://myumi.ch/6QxQg

post-ASCB hangover with @cianfrocco_lab @mcianfro

A success story! An Engineering School With Half of Its Leadership Female? How Did That Happen? https://www.chronicle.com/article/An-Engineering-School-With/246214/#.XMrxRpC7zak.twitter via @chronicle

HAIL promise effectively recruits low-income students to U-M https://record.umich.edu/articles/hail-promise-effectively-recruits-low-income-students-u-m#.XBEzBkmSNdw.twitter

PTMs, MAPs, and ABPs! Oh my! Super excited for the upcoming Saturday Subgroup on Patterning the Cytoskeleton at #ascbembo18 Hope to see you there!