Kirk Lohmueller

@klohmueller.bsky.social

Professor at UCLA in Ecology & Evolutionary Biology as well as Human Genetics. Traffic Ninja. Occasional runner... https://lohmueller.eeb.ucla.edu

Way to go Ricky & Nandita! It was such a joy to hear about this work developing and now to see it finally out! I remember, Nandita, that you pitched this in your chalk talk during your interview way back when:)

Nandita Garud@nanditagarud.bsky.social · 8mo ago

Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with @rwolff.bsky.social, whose insights and hard work made this possible. www.nature.com/articles/s41...

In the midst of the darkness, I am pleased to announce that UCLA will be hosting the upcoming Southern California Evolutionary Genetics (SCalE) conference on November 1! Registration & abstract submission is here: www.scalemeeting.org/home Deadline is October 13! Hope to see you at UCLA!

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The SCalE Meeting is a free, one day regional academic meeting focused on evolutionary genetics and genomics. This year's SCalE Meeting is hosted by UCLA, sponsored by the Institute for Quantitative ...

scalemeeting.org

Excited to be heading to St. Louis for #AOS2025! Be on the lookout for talks from our lab!: - Jenna McCullough (PD) and Jonah Alderson (grad) are up against each other on Wed. morning - Claire Geiman (grad) will present a poster Wed evening - Devon DeRaad (PD) will give a talk on Thur afternoon

Information on Jonah’s talk: Domestication genomics of the society finch (Wed, August 13 at 11:30-11:45 am), Genomics 2, Room Grand CInfo on Jenna’s talk: is structural white color rare in birds? Wednesday Aug 13 at 11:30-11:45, in Grand Ballroom AInfo on Devon’s talk: How are new species formed on islands? Superficial signals of sympatric ecological speciation actually result from massive and ongoing gene flow; Thursday, August 14 at 2:45-3:00pm, Room Grand FInfo on Claire’s poster: Strong selection maintains a narrow, stable avian tension zone in the Great Plains; Wednesday evening from 7-9pm, Poster Number 2

Having major FOMO about #SMBE2025 in my hometown… but I’m very proud that my postdoc, Susanna Gutierrez, will be presenting our work on inferring the selection history of adaptive introgression candidates in Peruvians at poster S12-P19. Please visit her during poster session 3 if you're interested!

Sad to be missing #SMBE2025. But, the lab will be represented with presentations from (all on Wednesday): Swetha Ramesh (at 11:50 in Symp 17, Noncoding) Chenlu Di (at 12:05 in Symp 17, Noncoding) Diana A Gomez (at 15:45 in Symp 19, Con Gen) Aina Mi Zurita (at 16:40 in Symp 22, Theory Adv)

Schlichta, Peischl & Excoffier reveal how purifying selection on deleterious mutations impacts diversity: while codominant variants create diversity dips, recessive mutations can preserve diversity in bottlenecks through pseudo-overdominance. 🔗 doi.org/10.1093/gbe/evaf107 #genome #evolution

Evolution of Functional Genomic Diversity During a Bottleneck

Abstract. Most species have been through population bottlenecks and range expansions, and the impact of these events on patterns of diversity has been well

doi.org

Kirk Lohmueller DominL uses patterns of archaic ancestry to infer degree of dominance. Provides statistical support for the presence of recessive deleterious mutations in the human genome. Up to 15% of the human genome may carry recessive deleterious mutations! 🧬 #HumanEvo25

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stdpopsim v0.3.0 is out! You can now mix and match your simulations of different demographic histories with published distributions of fitness effects along with gene annotations, and you can even throw in sweeps for good measure. Check out the new manuscript for more info: doi.org/10.1101/2025...

Accessible, realistic genome simulation with selection using stdpopsim

Selection is a fundamental evolutionary force that shapes patterns of genetic variation across species. However, simulations incorporating realistic selection along heterogeneous genomes in complex de...

doi.org

Registration is now open for the Gordon Research Seminar (GRS) on Ecological and Evolutionary Genomics in Tuscany, co-chaired by me and @jcbnunez.bsky.social! This meeting is a unique opportunity for early-career researchers to present their work and network. www.grc.org/ecological-a...

2025 Ecological and Evolutionary Genomics (GRS) Seminar GRC

The 2025 Gordon Research Seminar on Ecological and Evolutionary Genomics (GRS) will be held in Lucca (Barga), Lucca Italy. Apply today to reserve your spot.

grc.org