Exercise, Nutrition and GLP-1 Medicines to Improve Body Weight and Muscle Function in Heart Failure with Preserved Ejection Fraction - Current Heart Failure Reports

Purpose of Review This narrative review synthesizes current evidence on lifestyle, pharmacological, surgical, and multimodal interventions targeting muscle strength, body composition, and functional c...

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Protein intake, physical activity, and skeletal muscle outcomes in middle-aged adults: an observational study from the US | Journal of Nutritional Science | Cambridge Core

Protein intake, physical activity, and skeletal muscle outcomes in middle-aged adults: an observational study from the US - Volume 15

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Associations of length of stay with sarcopenia parameters in geriatric patients: age and sex differences in the oldest old - Aging Clinical and Experimental Research

Background Hospital-associated deconditioning is a contributor to secondary sarcopenia, which may be driven by prolonged hospital length of stay (LoS). This study investigated the bidirectional associ...

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Association of Testosterone With Lean Soft Tissue and Handgrip Strength Across Middle‐Aged Men

Background Testosterone declines by 0.4%–2% annually after the age of 30 and is potentially linked with muscle mass and strength. This study examined how testosterone levels are associated with hand...

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Circulating biomarkers in older adults with and without sarcopenia: a systematic review and meta-analysis

AbstractBackground. Sarcopenia, the age-related loss of muscle mass and strength, poses a significant health and economic burden. This systematic review an

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Plasma metabolomic and inflammatory profiles associated with low physical function in heart failure: an integrated cardiac–metabolic–muscular phenotype - GeroScience

Dysregulated metabolomic profiles (dysmetabolism) have been observed in patients with heart failure (HF). In this study, we investigated metabolomic profiling differences in HF with reduced physical-f...

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Skeletal and cardiac muscle longitudinal associations in the Baltimore Longitudinal Study of Aging (BLSA) - BMC Medicine

Background Sarcopenia, the age-related loss of skeletal muscle mass and function, has been linked to adverse health outcomes. Cross-sectional associations have been observed between skeletal and cardi...

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Effects of Nandrolone Decanoate on Muscle Strength, Body Composition and Bone Density: A Systematic Review and Meta‐Analysis

Background Despite ongoing interest in anabolic therapies for sarcopenia and cachexia, pharmacological interventions are being developed to counteract age- and condition-related losses of muscle mas...

onlinelibrary.wiley.com

22nd EuGMS CONGRESS | Lille, France - September 16-18, 2026

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The effects of bed rest on cardiometabolic health: A systematic review and meta‐analysis

Horizontal bed rest (HBR) and head-down tilt (HDT) are models of physical inactivity. In this systematic review and meta-analysis, we aimed to quantify changes in cardiometabolic outcomes during HBR ...

physoc.onlinelibrary.wiley.com

Effects of bed rest and immobilization on intramuscular and intermuscular adipose tissue: A systematic review

Muscle disuse caused by bed rest and immobilization is associated with muscle atrophy and insulin resistance, which might be related to increases in intramuscular fat (IntraMAT) and intermuscular fat...

physoc.onlinelibrary.wiley.com

Mortality and heart failure hospitalizations in heart failure with preserved ejection fraction compared to heart failure with reduced ejection fraction: a systematic review and meta-analysis

AbstractIntroduction. The global burden of heart failure (HF) is rising, with a shift towards more cases of heart failure with preserved ejection fraction

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Systemic Challenges in Sarcopenia Research: Implications for Meta‐Analytic Reliability and Clinical Translation

Sarcopenia, the age-related decline in skeletal muscle mass and strength, is a growing public health concern, yet several meta-analyses may be unreliable due to methodological and systemic challenges...

onlinelibrary.wiley.com

Probiotics, prebiotics, and synbiotics to counteract sarcopenia: where are we now and what challenges need to be faced? | Proceedings of the Nutrition Society | Cambridge Core

Probiotics, prebiotics, and synbiotics to counteract sarcopenia: where are we now and what challenges need to be faced?

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Food matrix in the context of muscle and whole-body protein synthesis: a scoping review - Nutrition & Metabolism

Background Understanding the impact of food matrix, the combination of nutrients, bioactive compounds, and physical characteristics in a food product, on muscle protein synthesis (MPS), could provide ...

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The effect of bed rest, unilateral limb immobilization and head‐down tilt on muscle protein synthesis: A systematic review and meta‐analysis

Muscle disuse leads to muscle atrophy and a decrease in muscle function that is primarily driven by reduced muscle protein synthesis (MPS). The aim of this systematic review and meta-analysis was to ...

physoc.onlinelibrary.wiley.com

14 postdoctoral fellowships to the BRIDGE – Translational Excellence Programme

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Clenbuterol induces lean mass and muscle protein accretion, but attenuates cardiorespiratory fitness and desensitizes muscle β2‐adrenergic signalling

Abstract figure legend This randomized controlled study investigated the effect of a 2 week treatment cycle of either oral clenbuterol or placebo in healthy young men. We found that clenbuterol: (1) ...

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Resistance training, but not leucine, increased basal muscle protein synthesis and reversed frailty in older women consuming optimized protein intake - GeroScience

Frailty, often linked to sarcopenia, involves reduced muscle strength and mass. While sarcopenia has multiple causes, impaired muscle protein synthesis may contribute. Leucine and resistance training ...

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Weighing the risk of GLP-1 treatment in older adults: Should we be concerned about sarcopenic obesity?

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been pivotal for obesity treatment, achieving 15–25 % weight loss over 12–24 months, but qu…

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