Robert Seaborne
@robertseaborne.bsky.social
Lecturer at King’s College London. Co-affiliate positions at The University of Copenhagen and The Blizard Institute London
It's been a long time since I sat down and enjoyed reading a paper cover-to-cover as much as this. Some cracking work and experiments. www.science.org/doi/10.1126/...
Mechanical loading induces the longitudinal growth of muscle fibers via a rapamycin-insensitive mechanism
mTORC1 does not always hold the key to unlocking the mechanical load-induced growth of skeletal muscle.
science.org
1 week left to apply! We are recruiting a Post‑Doc in Skeletal Muscle Molecular Physiology, Oslo, Norway Join our EMMA multi‑omics project on mitochondrial epigenetic memory in human muscle ageing. 4‑year position. Start May 2026. Apply: www.jobbnorge.no/en/available...
Experienced Post-Doc in Skeletal Muscle Molecular Physiology and Epigenetics (296037) | The Norwegian School of Sport Sciences
Job title: Experienced Post-Doc in Skeletal Muscle Molecular Physiology and Epigenetics (296037), Employer: The Norwegian School of Sport Sciences , Deadline: Wednesday, March 11, 2026
jobbnorge.no
We now have a lab website: muscleomicslab.github.io It has taken a while to write the code, update and is still a WIP, but it does a fair job of describing who we are, what we do and who funds us. We are always looking for collabs so please spread the word (& website)
The Seaborne Lab | Muscle-Omics
muscleomicslab.github.io
Final few days to apply for a postdoc pos. in our lab. If you have a passion for large data sets, data integration, sequencing and plenty of problem solving, then this could be for you! Initial 12 months, but with a further 19months available for the right candidate! www.jobs.ac.uk/job/DPK467/p...
Postdoctoral Research Associate in Computational Muscle Biology at King's College London
Apply for the Postdoctoral Research Associate in Computational Muscle Biology role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
jobs.ac.uk
Final few days to apply for a postdoc pos. in our lab. If you have a passion for large data sets, data integration, sequencing and plenty of problem solving, then this could be for you! Initial 12 months, but with a further 19months available for the right candidate! www.jobs.ac.uk/job/DPK467/p...
Postdoctoral Research Associate in Computational Muscle Biology at King's College London
Apply for the Postdoctoral Research Associate in Computational Muscle Biology role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
jobs.ac.uk
Please share far & wide. Looking for a #postdoc to get stuck in with a wide range of projects, with freedom to explore and lead the #computational #bioninformatics work 12 months to begin with, but for the right candidate we have funding for a further 19 months www.jobs.ac.uk/job/DPK467/p...
Postdoctoral Research Associate in Computational Muscle Biology at King's College London
Discover Postdoctoral Research Associate in Computational Muscle Biology jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.
jobs.ac.uk
Excited to present our recent work on myosin as a molecular target for genetic muscle diseases! Kudos to all authors, especially Elise, Fanny and @myofinlab.bsky.social @ucph.bsky.social
JCI Insight - Myosin inhibition partially rescues the myofibre proteome in X-linked myotubular myopathy
insight.jci.org
Please share far & wide. Looking for a #postdoc to get stuck in with a wide range of projects, with freedom to explore and lead the #computational #bioninformatics work 12 months to begin with, but for the right candidate we have funding for a further 19 months www.jobs.ac.uk/job/DPK467/p...
Postdoctoral Research Associate in Computational Muscle Biology at King's College London
Discover Postdoctoral Research Associate in Computational Muscle Biology jobs and more in higher education on jobs.ac.uk. Apply for further details on the top job board.
jobs.ac.uk
Recruiting a comp PDRA for the lab 🚨 Working on multiple projects using integrated multi omics in bulk & single cell level Passion for data, coding, bioinformatics & keen to lead our labs comp workflow 12 months in first instance but extendable for further 19 months my.corehr.com/pls/coreport...
my.corehr.com
We will soon be looking for a comp biologist or bioinformatician to work on a number of linked projects within the lab - main focus is on molecular control of muscle Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!
Little under a week left to apply for this position to come and lead some cool experiments in muscle biology in London!
Robert Seaborne@robertseaborne.bsky.social · 10mo ago🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...
We are looking for an enthusiastic MD or PhD to work on a postdoc project on the molecular mechanisms underlying human hibernating myocardium and ischemic cardiomyopathy. If interested send me an email! #heart #cardiomyopathy #sarcomere
14 postdoctoral fellowships to the BRIDGE – Translational Excellence Programme
employment.ku.dk
🚨Second position available in the lab. Through MRC DTP programme we have a PhD opportunity working on brain-muscle axis, analysing shared/divergent molecular signatures across bulk tissue and single cell. Please spread the word! kcl-mrcdtp.com/project/the-...
The brain-muscle epigenetic interplay in neuromuscular disease - MRC DTP
Background: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease marked by progressive motor neuron loss. Emerging evidence suggests a critical, previously underappreciated role for skeletal muscle in ALS onset and progression, highlighting pathological and molecular interplay between brain and muscle. However, systematic, high-resolution molecular analyses across these tissues remain scarce. This project will use advanced […]
kcl-mrcdtp.com
Postdoc opportunity in muscle cell biology! You would not only be involved in an ambitious project but would also help develop cutting edge methods! Highly recommended! @robertseaborne.bsky.social
Postdoctoral Research Associate in Muscle Biology and Genomics | King's College London
kcl.ac.uk
🚨Hiring a 2yr postdoc in the lab work on muscle biology, genomics & ALS. Expertise in the above advantageous, but work ethic, desire to learn/develop and being a good scientist/person more important Good collab with @droch.bsky.social so travel to CPH involved as well www.kcl.ac.uk/jobs/126245-...
Postdoctoral Research Associate in Muscle Biology and Genomics | King's College London
kcl.ac.uk
Denmark is a country very difficult not to fall in love with www.science.org/content/arti...
I thought science hinged on prestige. Moving abroad made me reassess my priorities
In Denmark, this Ph.D. student fell in love with an egalitarian society that values work-life balance
science.org
Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!
King's Faculty of Life Sciences & Medicine@kingslsm.bsky.social · 12mo agoCongratulations to Dr Robert Seaborne @kingscollegelondon.bsky.social who has been awarded a New Investigator Grant from the Medical Research Council (MRC), which will support his work on understanding the role of skeletal muscle in motor neurone disease. Read more ➡️ www.kcl.ac.uk/news/dr-robe...
Congratulations to Dr Robert Seaborne @kingscollegelondon.bsky.social who has been awarded a New Investigator Grant from the Medical Research Council (MRC), which will support his work on understanding the role of skeletal muscle in motor neurone disease. Read more ➡️ www.kcl.ac.uk/news/dr-robe...
Kings Prize Fellowship is now open, awarding funds for 18-24 months to an outstanding postdoc. If keen to come to KCL and work on molecular dynamics of single myofibers in healthy/diseased contexts, drop me a message! www.kcl.ac.uk/assets/resea...
kcl.ac.uk
Fantastic opportunity for an ECR to establish their own group!
Karolinska Institutet@ki.se · last yr.Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. 🔗 All positions: ki.se/en/about-ki/...
Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence
KI to recruit junior researchers with a focus on excellence
On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility. As one of Europe’s leading medical universities, KI offe...
news.ki.se
Epigenetic effects of paternal environmental exposures and experiences on offspring phenotypes www.sciencedirect.com/science/arti....
Epigenetic effects of paternal environmental exposures and experiences on offspring phenotypes
Recent decades have revealed increasing evidence for epigenetic inheritance through paternal environmental exposures and experiences, affecting offspr…
sciencedirect.com
A pleasure to play a very small part in a very large story (and just as big collaboration). From @nireynon.bsky.social team. Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration www.cell.com/cell-reports...
Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration
Jacques et al. conducted a thorough meta-analysis integrating multi-omics data from over 1,000 participants to identify distinctive molecular signatures in human skeletal muscle adaptation to various ...
cell.com
A wonderful time celebrating a fair few years of quality science! A few brain cells, papers, grants, experiments and beers developed, created and shared amongst these lads over the years!
Wow! Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM www.nejm.org/doi/full/10....
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease | NEJM
Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality ...
nejm.org
Another beautiful collaboration 🔬💪 Proof-of-principle of getting both functional and proteomics data from a single myofiber - even from our tiny nemaline myopathy ones! Thanks for all the fun times in the lab @robertseaborne.bsky.social
Robert Seaborne@robertseaborne.bsky.social · last yr.Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof-of-principle study Another collab between the labs @droch.bsky.social @adeshmukh.bsky.social physoc.onlinelibrary.wiley.com/doi/10.1113/...
Excited to share another great collaborative effort — we successfully combined single muscle fiber proteomics with functional assays in the same fiber! This integrated approach allows a direct link between molecular composition and functional performance at the single cell/fiber level.
Robert Seaborne@robertseaborne.bsky.social · last yr.Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof-of-principle study Another collab between the labs @droch.bsky.social @adeshmukh.bsky.social physoc.onlinelibrary.wiley.com/doi/10.1113/...
Integrated single-cell functional-proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof-of-principle study Another collab between the labs @droch.bsky.social @adeshmukh.bsky.social physoc.onlinelibrary.wiley.com/doi/10.1113/...
Integrated single‐cell functional‐proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof‐of‐principle study
Abstract figure legend SMPFO uniquely develops data relating to the biophysical state of the sarcomeric protein, alongside global proteome profiling, on a single myofibre basis. Using this approach w...
physoc.onlinelibrary.wiley.com
New collaborative paper from @droch.bsky.social group, combining SkM biopsy, single fascicle and single myofiber biophysical and molecular experiments in T2DM link.springer.com/article/10.1...
Dysregulated skeletal muscle myosin super-relaxation and energetics in male participants with type 2 diabetes mellitus - Diabetologia
Aims/hypothesis Disrupted energy balance is critical for the onset and development of type 2 diabetes mellitus. Understanding of the exact underlying metabolic mechanisms remains incomplete, but skele...
link.springer.com
