My first paper has been published in Hippocampus! bsky.app/profile/masa... Thank you Caswell and Claudia for your support!

Caswell Barry@caswell.bsky.social · 2w ago

Masa's paper is out in Hippocampus. The left-right alternation of hippocampal theta sequences at T-maze choice points, much loved as a 'planning' signal, falls straight out of MEC dynamics. Well done @masahironakano.bsky.social, fun project with @clopathlab.bsky.social doi.org/10.1002/hipo.70131

This is an absolutely amazing piece of work!

Abraham Zelalem Vollan@azvollan.bsky.social · 2mo ago

Now in Science: How does the brain’s navigation system allocate its limited representational resources during behavior? We found that grid cells sweep toward locations of interest, providing a potential mechanism for allocating spatial attention in the cognitive map.🧵 science.org/doi/10.1126/...

New preprint from the lab! Behavioral and neural mechanisms for stochastic choices in mixed-strategy games: doi.org/10.64898/202... We use game theoretic tasks, cross species comparisons, modelling strategies, and mesoscale imaging to reveal a cortical mechanism for unpredictable choices.

This project builds on work establishing the behaviour done at Champalimaud in Lisbon with @michaelfsp.bsky.social, Beatriz Godinho, Christian Machens, and @ruimcosta.bsky.social : www.biorxiv.org/content/10.6...

Flexible route planning and rapid structure learning by mice in complex environments

Action selection using predictive models of the environment plays a fundamental role in human and animal behaviour, yet is poorly understood at circuit and algorithmic levels. Spatial navigation is an...

biorxiv.org

It has been super fun to work on this, where we learned that: 1) Mouse PFC is needed for model-based override of habits. 2) Separate PFC populations encode a 'policy' and the current 'value'. 3) The policy and value codes alternate theta sweeps towards the goal. ...and much much more!

@peterdoohan.bsky.social · 4mo ago

How do brains plan actions towards goals? To get at this question we studied mice navigating complex mazes as goals changed on every trial 🧵 Work with @thomasakam.bsky.social @behrenstimb.bsky.social @kristorpjensen.bsky.social now on BioRxiv: www.biorxiv.org/content/10.6...

Are you a neuroscientist with great coding skills, or a software engineer interested in the brain? We are recruiting for a research software engineer to help us build pipelines to process weeks of neural and behavioural recordings from freely moving animals. More details: bit.ly/rse-2026a

📢📢 Announcing this year's conference on the Mathematics of Neuroscience & AI (Rome, 9-12th June). We’ve got a stellar line-up and venue, and invite everyone to join: www.neuromonster.org

We’re hiring a Group Leader! Join us to lead a transformative initiative in human systems neuroscience. Find out more and apply ⤵️ www.sainsburywellcome.org/content/curr...

Junior scientists 👉 applications are open for our workshop on the mechanistic basis of #cognition. 🧠 🤝 Joint sessions with our #TheoreticalNeuroscience workshop ✈️ Hotel, meals + reasonable travel expenses covered Apply by May 7 ➡️ janelia.news/CNW26 @michaelreiser.bsky.social @jvoigts.bsky.social

I’m super excited to finally put my recent work with @behrenstimb.bsky.social on bioRxiv, where we develop a new mechanistic theory of how PFC structures adaptive behaviour using attractor dynamics in space and time! www.biorxiv.org/content/10.1...

Great paper by @jonathannicholas.bsky.social and @marcelomattar.bsky.social ! A related discussion we had in our lab recently is whether there exists convincing evidence that mice use episodic memory - refs are welcome if anyone knows relevant work!

Jonathan Nicholas@jonathannicholas.bsky.social · 2y ago

Why do we remember so many details of our experiences even when it is unclear if we will actually ever need them? In a new preprint, @marcelomattar.bsky.social and I asked whether this property is adaptive, because what will be relevant in the future often (usually?!) isn’t apparent.

Amazing work by Mehran, @sonjahofer.bsky.social, and colleagues, characterizing neural mechanisms underlying explore/exploit behaviours!

Sonja Hofer@sonjahofer.bsky.social · 2y ago

Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...

New paper from the lab! Mathias Sablé-Meyer used behavior, fMRI and MEG to study the mental representation of geometric shapes (quadrilaterals ranging in regularity from squares and rectangles to random figures). www.biorxiv.org/content/10.1...

For my first Bluesky post, I'm very excited to share a thread on our recent work with Mitra Javadzadeh, investigating how connections between cortical areas shape computations in the neocortex! [1/7] www.biorxiv.org/content/10.1...

Dynamic consensus-building between neocortical areas via long-range connections

The neocortex is organized into functionally specialized areas. While the functions and underlying neural circuitry of individual neocortical areas are well studied, it is unclear how these regions op...

biorxiv.org

663 days since the senseless tragedy that took An, we present a manuscript that reports some of the discoveries that she left us. www.biorxiv.org/content/10.1...

Targeted stimulation of motor cortex neural ensembles drives learned movements

During the execution of learned motor skills, the neural population in the layer 2/3 (L2/3) of the primary motor cortex (M1) expresses a reproducible spatiotemporal activity pattern. It is debated whe...

biorxiv.org

I wrote an introduction to RL for neuroscience last year that was just published in NBDT: tinyurl.com/5f58zdy3 This review aims to provide some intuition for and derivations of RL methods commonly used in systems neuroscience, ranging from TD learning through the SR to deep and distributional RL!