The daughter of Ming the Merciless made 8-year-old me realize I wanted a baddie.

I miss that kid who pet the dogs.

How I imagine Chicago Pope deciding to excommunicate SSPX.

I get to work with these fine folks @wheelerlab.org and this is Big News!

RepeatMasker Project@repeatmasker.bsky.social · last mo.

A New Open Foundation for TE Research: GIRI is transitioning the full Repbase collection to an open-access license and joining the Dfam effort to help build a unified open resource for transposable element research. Full announcement: tinyurl.com/48665xss

#makeaterriblecomicday2026

Another crucial bit of context here is that Edmund Pettus was an officer in the CSA and a Grand Dragon of the KKK, and they have never changed the name of this bridge. I had to live Jackson, MS, next to the Ross Barnett Reservoir, named for another horrid racist.

Isaac G. Bryan@ib2real.bsky.social · 3mo ago

Thousands are marching in Selma calling for a full restoration of the voting rights act.

I wrote an Eagle's cover about how my AI girlfriend doesn't work. It's called "Glitchy Woman."

I've created py4bfx.com to host all the free YouTube videos I've made for my book Mastering Python for Bioinformatics (O'Reilly, 2022). This material will be used by the NCSU Bioinformatics Research Center for an upcoming introduction to programming for biology. #python #bioinformatics #programming

If Mark Ruffalo ate too much, he'd be called Mark Stuffalo.

👁 eiz@punishingdaisies.bsky.social · 3mo ago

if mark ruffalo was really into scent he'd be called mark huffalo

I get it. I once fell in love with spellcheck.

"I ain't nothing but tired" I hear you, Boss.

When my wife says "I moved that thing that was in the way" she means "I put it in the already crowded garage where you store too many bicycles, and I probably put it on your workbench that is barely visible under all your half-abandoned projects."

Almost to 2K subscribers on my YouTube channel www.youtube.com/@kyclark

I don't want to brag, but the dentist says I'm a big salivator.

I’m judging people who use Times New Roman on their phone lock screen.

1990: I, an 18-year-old male, watch the US invade the Middle East and fear that I'll be drafted to fight. 2026: I, a 53-year-old, watch the US invade the Middle East and fear that my 18-year-old son will be drafted to fight.

Has anyone checked the tariff shelf this morning?

Please spread the word: We invite applications to a two-week Computational Biology workshop in Singapore, June 14-27. This NSF-funded workshop brings together 16-20 US grad students with international peers. Apply by March 21: compbioasia.net 🧵 Details below:

I've been thinking about making friends with a neighborhood corvid. Maybe hold out some peanuts in my hand and see what happens.

Looking at used bicycles on Craigslist just to feel something.

Shout out to Fishbone, who was singing to my white-college-boy ass back in the early 90s about fascism. Not something I ever thought about growing up, and they were trying to get me to see it.

My ride share car smells like air freshener and pot. Reminds me of the summer I lived in a house with six band mates and there was a cinnamon air freshener in the bathroom and the keyboard player came out and said “Mmm cinnamon dump!

I've release a new user interface for mdrepo.org, an open repository of molecular dynamic simulations for proteins, written in Elm (specifically Elm Land). The original version used React/JS and was slow and failed with exceptions. The Elm version should have zero runtime exceptions. #elm-lang

Tried to call my step-dad and got his voice mail with the message recorded by my mom, who died in June.

A friend shared a lovely Dijkstra essay. It's short enough to read in a few minutes, and is damning of the current attempt to replace our brains with AI generated writing and vibe coding. www.cs.utexas.edu/~EWD/transcr...

I've become increasingly disappointed my publisher, @oreilly.bsky.social, leaning so heavily into vibe coding. They canceled my Rust course in which I attempt to methodically teach how to learn Rust by writing it oneself. They fired the really good acquisition editors who brought me on board.

O'Reilly@oreilly.bsky.social · 11mo ago

“Our focus this time is going to be on agentic coding. We’re moving beyond simple chatbots to AI systems that can plan, execute, and collaborate—transforming how we build software.” Read on The AI Journal: bit.ly/3Jzk5wv @timoreilly.bsky.social

A friend would ride with his mom to drop his sister off for piano lessons. Every time, his mom asked him if he'd like to take lessons, too. Every time, he said no. One day, he decided he would say yes the next time his mom asked. She never did, and he never studied the piano.

I don't understand the government taking 10% of Intel profits. Like, isn't that what taxes are supposed to be?

My one food service experience was 27 years ago at a Cracker Barrel in Lewisville, TX, my last semester in college after my folks kicked me off the payroll after a huge fight over my girlfriend.

Culture Crave 🍿@culturecrave.co · 12mo ago

Cracker Barrel has updated their logo for the first time in 48 years

I like Weird Al but not weird AI and this is a very confusing time for me.