Not only did Jack Szostak give an amazing and inspiring talk at the NIH Intramural Research Program, but he engaged wholeheartedly with students, postdocs and PIs alike. Thanks so much Jack. We look forward to recreating this experience, hopefully not in too distant future.

Now out in Nature! We visualize infection of the RNA virus RSV in real-time with single-vRNP resolution to understand how RSV establishes viral factories, biomolecular condensates that act as sites of viral replication. A huge collaborative effort led by Dhanushika Ratnayake! rdcu.be/e1bBW

Pre-assembly of biomolecular condensate seeds drives RSV replication

Nature - Viral ribonucleoprotein–viral protein networks form pre-replication centres that nucleate viral factories and drive respiratory syncytial virus replication.

rdcu.be

A giant thank you to @drjz.bsky.social and @vidigaljoana.bsky.social! It takes a village to celebrate #RNAday

Joe Ziegelbauer@drjz.bsky.social · last yr.

NIH had fun celebrating another #RNAday. Thanks to @vidigaljoana.bsky.social for organizing this great event and @slwolin.bsky.social for building a strong RNA community.

New paper out! We found that RSV remodels host translation without inducing global shutdown 🦠 doi.org/10.1186/s129...

An intuitive visualization of the regulatory layers influencing the stoichiometry of a protein complex. pmc.ncbi.nlm.nih.gov/articles/PMC...

Our new paper is out on BioRxiv today! 🦠 Using polysome profiling and RNA-seq, we report that polysome-associated host mRNAs are reorganized during RSV infection enhancing translation of virus-resembling transcripts. doi.org/10.1101/2024...

Respiratory Syncytial Virus (RSV) optimizes the translational landscape during infection

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

doi.org