Check out this amazing work led by the incredible bioinformatics guru @isaacmtzu.bsky.social supervised by @ceiabreu.bsky.social in collaboration with our lab @amyhbuck.bsky.social!! #argonautes #AGOs #sRNAs #nematodes

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

Comparative transcriptomics reveals an extracellular worm argonaute as an ancestral regulator of LTR retrotransposons. https://www.biorxiv.org/content/10.1101/2025.09.22.674508v1

Super excited to see our work shared with the scientific community! We know #Argonaute proteins can be extracellular, but can they be transferred to recipient cells and can they function? Happy reading!

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival https://www.biorxiv.org/content/10.1101/2025.04.01.646544v1

Very excited to share this collaborative work led by Kyriaki Neophytou. An extracellular Argonaute from a nematode parasite is transmitted to host cells and the non-vesicular form is functionally important (and now a vaccine candidate). An Argonaute vaccine... who would have thought.

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival https://www.biorxiv.org/content/10.1101/2025.04.01.646544v1

I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.