@laurawesseldijk.bsky.social

Thank you @rafaelahlskog.bsky.social and @aysuo.bsky.social for having me and for the opportunity to discuss our work! Check out the podcast in the quoted tweet below, and check out the paper we discussed here: www.nature.com/articles/s41...

Socio-economic status is a social construct with heritable components and genetic consequences

Nature Human Behaviour - Abdellaoui et al. synthesize genomic evidence on the link between socio-economic status and heredity. They show how social stratification may create selection pressures,...

nature.com

ESSGN@essgn.bsky.social · 3mo ago

Big news! @dr-appie.bsky.social returns to Born and Raised this week, and besides talking about how social inequality and genetic structure affect each other, he also has a cool surprise for us! Can you guess what it is?

The question I get most after talks about music and mental health: "But what about people who just listen to music?" Most of us never pick up an instrument, we engage with music through listening... So we studied it. New paper on music listening, mental health & genetics 🎵 doi.org/10.1016/j.ja...

Does listening to music relate to mental health in the general population: a genetically informed approach

While some people actively play instruments, most primarily engage with music through listening. Although intervention studies consistently report pos…

sciencedirect.com

In this week's episode, we talk to @laurawesseldijk.bsky.social about genetics, musicality, metal, mental health. But more importantly, we finally uncover @dr-appie.bsky.social's secret music career and learn about Laura's childhood playing trombone on a horse while doing a headstand??

@laurawesseldijk.bsky.social · 3mo ago

There was a lot of laughter during this conversation and a few secret confessions... But we also had some great discussions about musicality, genetics, Beethoven and public outreach, mental health, and music genres... Thank you @rafaelahlskog.bsky.social and @aysuo.bsky.social for having me! 🎶

There was a lot of laughter during this conversation and a few secret confessions... But we also had some great discussions about musicality, genetics, Beethoven and public outreach, mental health, and music genres... Thank you @rafaelahlskog.bsky.social and @aysuo.bsky.social for having me! 🎶

ESSGN@essgn.bsky.social · 3mo ago

What's the deal with musicality and genetics? This week, Born and Raised went to talk to Laura Wesseldijk. There's something here for both metalheads, horse riding enthusiasts and trombonists!

First time on Bsky and first big announcement! I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature. Our manuscript is here: www.nature.com/articles/s41....

Estimation and mapping of the missing heritability of human phenotypes - Nature

WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...

nature.com

With sequencing of Hitler's DNA making headlines, time for a reminder: analysing a polygenic score from a dead historically-significant figure won't give new insights into that person's behaviour. In a brief paper last year, we used Beethoven's genome to directly illustrate the fallacies involved.🧪👇

Notes from Beethoven’s genome

Wesseldijk et al. compare the genomic information collected from Ludwig van Beethoven with population-based datasets used to quantify musical achievement.

cell.com

Debunking “nature versus nurture”, a thread. Different people in a population carry variations in their DNA; the science of genetics makes it possible to assess if/how that correlates with individual differences in any observable trait, from medical conditions to aspects of cognition/behaviour.🧪1/9

Side-by-side images of the front covers of two magazines, one called Nature, the other called Nurture.

Music science offers multiple examples of nature/nurture interplay. Here’s just one, from @laurawesseldijk.bsky.social. An enriched childhood environment is associated with higher music achievement in adulthood. But such effects are amplified in people who have a genetic predisposition. 8/9 [More 👇]

Music and Genetics

The first part of this review provides a brief historical background of behavior genetic research and how twin and genotype data can be utilized to st…

sciencedirect.com