Linda Horianopoulos
@linder-surprise.bsky.social
Assistant professor in the Department of Food Science at the University of Guelph How can we harness the diversity of metabolism and other characteristics of yeasts for food applications? https://yeastlab.mystrikingly.com/
Backed by $8M in federal funding, Dr. Chris Todd Hittinger will be the new Eddie Goldenberg Research Chair of Canada in Biodiscovery, Biodesign and Bioproduction at #UofG as part of the Canada Global Impact+ Research Talent Initiative. His appointment begins on July 1, 2027: https://uoguel.ph/3nw8s
A reminder to budding yeast researchers: if you use the "GAPDH" promoter to drive constitutive expression, please be careful about how you describe this. The gene GPD1 encodes glycerol-3-phosphate dehydrogenase, not Glyceraldehyde-3-phosphate dehydrogenase. The TDH3 promoter is probably what you use
If you have so much work to do that you feel you need AI in order to get it all done: you don't. You need a union.
Kicking of #CanFunNet26 today!🍁🍄 canfunnet.conferences.uwo.ca Be sure to check out lab members Adrian Ciemniecki and Laura Delage who will both be speaking in Fungal Genetics and Genomics II today!
CanFunNet Conference | 6th Annual CanFunNet Fungal Biology Conference
This year, we are excited to go west for the first time with CanFunNet for a virtual meeting hosted by the University of Alberta in Edmonton. Continuing in the footsteps of previous meetings, our prog...
canfunnet.conferences.uwo.ca
FYI, @who.int published a new blueprint to help countries respond to the burden of fungal disease & antifungal resistance. The Blueprint prioritizes interventions under four interlinked domains and identifies 12 catalytic entry points to guide interventions: who.int/news/item/30...
New WHO report outlines critical steps to confront fungal disease and antifungal resistance
The World Health Organization (WHO) today published a new blueprint to help countries respond to the increasing burden of fungal disease and antifungal resistance – one of global health’s most underes...
who.int
Dear CanFunNet community, we will be hosting a workshop on science communication with experts in the field. You won't want to miss it!
Our recent work with @linder-surprise.bsky.social and the @rokaslab.bsky.social has been featured as a research highlight on the Great Lakes Bioenergy Research Center (GLBRC) page: www.glbrc.org/research/hig...
Trait syndrome links cell structure to metabolic efficiency across yeast subphylum
Researchers analyzed a dataset of glucose-induced extracellular acidification rates — as a proxy for glycolytic rates — and phenotypic variation across 282 species with Saccharomycotina to test whethe...
glbrc.org
PSA for trainees cold emailing with interest in joining a lab: Be careful about your use of LLMs in writing these emails!! It is now *extremely* common to get emails with a bizarrely-detailed, clearly-LLM take on a paper finding or with specific phrases pulled from the lab website. Don’t do this!
Come join the Horianopoulos Lab! I am recruiting a graduate student to join my research group focused on the genetic determinants of yeast stress responses. How to apply: Email lhoriano@uoguelph.ca by July 15, 2026 with a CV and cover letter. Subject line: “Horianopoulos lab graduate position”
A new study out with @linder-surprise.bsky.social and @rokaslab.bsky.social in iScience across ~300 yeast species confirms the correlation between glucose uptake rate and cell surface-to-volume (SA:V) ratio, but suggests a link to other traits (growth rates and genome size). doi.org/10.1016/j.is...
A trait syndrome ties cell morphology to glycolysis across the yeast subphylum
Co-variation of traits provides fundamental insights into constraints governing their evolution. An inverse correlation between glucose uptake rates (…
sciencedirect.com
Happy to share our new paper showing a correlation between cell metabolism and morphology across the budding yeasts: www.cell.com/iscience/ful...
A trait syndrome ties cell morphology to glycolysis across the yeast subphylum
Biological sciences; microbial genomics; evolutionary biology; phylogenetics
cell.com
3/ We were both happily shocked. Weird observations are often biology's way of telling you a secret, so, we followed on. That led to MitRatiNa: a ratiometric fluorescent reporter for mitochondrial Na+.
Interested in how #fungi came about on this planet? If so, take a look at my new article that just came out in @annualreviews.bsky.social. doi.org/10.1146/annu...
The Origin and Early Evolution of Fungi: Challenges, Inferences, and Principles
Fungi are widespread on our planet and essential for life as we know it, but how did they come about? Their last common ancestor lived hundreds of millions of years ago, but its characteristics, and t...
doi.org
Last chance!! Abstract submission deadline is tonight at 11:59 eastern. 📆 Don't miss this chance to share your fungal research and network with the Canadian Fungal Research community!🍄
CanFunNet@canfunnet.bsky.social · 3mo agoOnly three days to register and submit an abstract! We look forward to seeing you all at our low-cost virtual meeting! #CFN26
There's still one week left to submit an abstract #CanFunNet26 🍄 🗓️ Come tell us about the cool fungal research you've been up to at this low cost, virtual meeting!
CanFunNet@canfunnet.bsky.social · 3mo agoOnly one week left to submit an abstract or register for CanFunNet! You won't want to miss #CFN26 ! Link here: canfunnet.conferences.uwo.ca
Pleased to share the newly launched lab website, check it out: yeastlab.mystrikingly.com
Horianopoulos Lab on Strikingly
Microbiology yeast laboratory at the University of Guelph
yeastlab.mystrikingly.com
Meet Aleeza Gerstein, one of our plenary speakers! Dr. Gerstein's research applies evolutionary principles and statistical methods to understand the evolution of human fungal pathogens in the context of drug resistance and chronic infection. Register today for #CFN26 to hear more from Dr. Gerstein.
Meet Michael Pyne, one of our plenary speakers! Dr. Pyne's research aims to discover, produce, and engineer plant natural product pathways in microbial systems, combining synthetic biology with classical retrosynthesis to design novel routes to pharmaceutical scaffolds. Register for #CFN26 today!
In issue 10: Convergent evolution of aerobic fermentation CIN promotes migration & invasion via EFEMP1 secretion SenSet resource defines cell-type specific senescence signatures ... Cover: @franbottanelli.bsky.social and colleagues link.springer.com/journal/4431...
The proposed closure of the Beltsville Agricultural Research Center threatens the U.S. National Fungus Collections—vital for agriculture, biosecurity, and research. The Mycological Society of America calls for continued preservation and enhanced support! msafungi.org/wp-content/u...
msafungi.org
Meet Jan Van Kan, one of our plenary speakers! Dr. Van Kan's research focuses on necrotrophic fungal pathogens of plants investigating molecular mechanisms of infection, and the development of strategies to combat plant diseases. Register today for #CFN25 to hear more from Dr. Van Kan.
Meet Nancy Keller, one of our plenary speakers! Dr. Keller's research focuses on the discovery of secondary metabolite synthases and their chemical products and the intrinsic development of antifungal resistance in Aspergillus pathogens. Register today for #CFN25 to hear more from Dr. Keller.
There's a story behind every project that doesn't get fully captured in the final paper. Check out our "behind the paper" accompanying our paper on convergent evolution of aerobic fermentation in yeast. communities.springernature.com/posts/learni... @hittingerlab.bsky.social @rokaslab.bsky.social
Learning the rules of metabolic innovation in yeast evolution
communities.springernature.com
It's Mycology Monday! 🍄 Which reminds me! CanFunNet registration is now open: canfunnet.conferences.uwo.ca/registration If you study fungi, this broad fungal conference is a great one to attend (or present at).
With @linder-surprise.bsky.social and the @rokaslab.bsky.social, we evaluated glycolytic rates in 299 species using a newly developed ECAR assay. Genes retained by S. cerevisiae were highly expressed in Sat. dispora, indicating the CE of aerobic fermentation. link.springer.com/article/10.1...
Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes - The EMBO Journal
As the tree of life becomes increasingly accessible to molecular investigations, describing mechanisms underlying evolutionary convergence and constraint will be crucial to understanding diversificati...
link.springer.com
🧰 MoClo toolkit 2.0: Updated modular #Yeast cloning system enables mix-and-match assembly of parts for protein secretion & surface display. New anchors, fluorescence detection & secretion boosters streamline #biotechnology applications 🧬 #YeastResearch 🧪 #SGD 🔬 www.yeastgenome.org/reference/S1...
Dear CanFunNet community, we are happy to announce that abstract submission and registration are now open! Here is the link: conference.has.uwo.ca/Register/def.... #CFN26
So pleased to share that this project identifying convergent evolution of aerobic fermentation in a poorly characterized genus of yeasts (Saturnispora) is now out in @embojournal.org @hittingerlab.bsky.social @rokaslab.bsky.social @glbioenergy.bsky.social link.springer.com/article/10.1...
Convergent evolution of aerobic fermentation through divergent mechanisms acting on key shared glycolytic genes - The EMBO Journal
As the tree of life becomes increasingly accessible to molecular investigations, describing mechanisms underlying evolutionary convergence and constraint will be crucial to understanding diversificati...
link.springer.com
