Ludovic S. Mure
@ludovicmure.bsky.social
☀️👁⚡️🧠 Studying how #light affects us | 🇫🇷 Group leader #newPI @unibe.ch and Inselspital 🇨🇭| previously @inserm.fr and @salkinstitute.bsky.social
🦀🦐🐟 Not much of a lunch but more than enough for a first lesson in animal systematics. #SantaCesareaTerme🇮🇹
1/ Excited to share our latest work on the deleterious impact of Alzheimer’s disease on light perception. 🧵 #Alzheimers #Neuroscience #Retina rdcu.be/fnyPD
Functional and morphological alterations of light detection circuits in postmortem retina from donors with different stages of Alzheimer’s-like pathology
Communications Biology - Ex vivo recordings and histology of postmortem human retina reveal selective dysfunction of ipRGC light-detection circuits in Alzheimer’s disease, highlighting...
rdcu.be
Fascinating article on disembodied human brains and the growing potential of ex vivo human neural tissues for research and drug testing. Not alive, but not dead: disembodied human brains used for drug testing | Science | AAAS shorturl.at/4CfZw
Not alive, but not dead: disembodied human brains used for drug testing
By restoring some functions to intact brains from deceased donors, the startup Bexorg hopes to create a better drug development test bed for neurodegenerative diseases
science.org
Charles Clément (1889-1972) - Sensuality and Terroir - interesting mix on display in the lovely setting of the townhall forum #Lausanne
Recent studies have revealed the synchronization of neuromodulators including norepinephrine, serotonin, acetylcholine, dopamine, and histamine during sleep. A new #ScienceReview explores what potential role the synchronization of these oscillations may play in health. https://scim.ag/3PEGdsW
The oscillatory biology of sleep: Linkage to dementia
During wakefulness, neuromodulators operate largely independently to support behavior and cognition. By contrast, sleep reorganizes their activity into a coordinated brain rhythm. During sleep, the ma...
scim.ag
Swiss "May snow" (wild narcissus flowers bloom) at Les Pleiades
#JobAlert! #PostDoc and #PhD positions at @unibe.ch / @inselgruppe.bsky.social on an SNSF-funded project studying #ipRGC alteration in #Alzheimer’s disease combining #retina physiology, circuit mapping, and transcriptomics. PostDoc: tinyurl.com/v3rpzr72 PhD: tinyurl.com/4wxytkcp
Postdoc ad.pdf
tinyurl.com
Pour cet été, je prépare une série de 10 émissions d'une heure sur les "rumeurs qui ont changé le monde". On va prendre des rumeurs, fausses info voire carrément des théories du complot, qu'on va détricoter. Je suis trop contente, MAIS je galère et j'ai besoin de votre aide pour trouver des FEMMES
a man in a suit and tie is singing into a microphone and the words `` where are youu '' are written below him .
Alt: a man in a suit and tie is singing into a microphone and the words `` where are youu '' are written below him .
media.tenor.com
#Circadian disruption is well linked to Alzheimer’s disease but how does it shape pathology? In this invited editorial in SLEEP, I discuss Duncan et al.’s study showing that dim light at night reshapes microglial state and amyloid vulnerability. #Alzheimers #LightPollution shorturl.at/BJzTE
Modern lights on neuropathology of Alzheimer’s Disease
Ludovic S Mure; Modern lights on neuropathology of Alzheimer’s Disease, Sleep, , zsag080, https://doi.org/10.1093/sleep/zsag080
academic.oup.com
Light, colour, and motion. Afternoon at the exhibition “Peintures françaises 1800–1945. Anatomie d’une collection” at the #MCBA in #Lausanne. A beautiful walk through the evolution of French painting, from realism to impressionism and early modernism, based on works from the museum’s own collection.
Michel Winterberg’s “Melting – the show must go on!”, a block of ice formed by a computer cooling system slowly dissolving under the eye of a webcam or the problem of digital economy thermal footprint. “Si la neige ne revenait pas” (If the snow were not to return) at Pyxis, #Lausanne
Why doesn’t #light reset our #circadian clock during the day? The gate isn’t only in the brain (SCN), but also in the eye. The #ipRGCs limit their own firing, which shapes when light can produce a phase shift. rdcu.be/eZ8cH
ipRGC properties prevent light from shifting the SCN clock during daytime
Nature - The inability of intrinsically photosensitive retinal ganglion cells to shift the circadian clock in the suprachiasmatic nucleus during daytime is caused by light-dependent depolarization...
rdcu.be
David Bowie nous a quittés il y a déjà 10 ans aujourd'hui... Prenez un casque, installez-vous confortablement et ouvrez ces 10 heures de documentaires, d'entretiens pour plonger à la source du génie de cet homme aux mille facettes. ➡️ l.franceculture.fr/GVi
Vallotton Forever - Retrospective of the versatile Felix Valloton for the 100th anniversary of his death @MCBA #Lausanne
🎉 Save the Date! The 37th Annual SLRCH Meeting will take place 3–5 June 2026 at the University of Milan, La Statale, Italy! Join us for three inspiring days of science, collaboration & connection ! Stay tuned for more details on submissions, Trainee Day, and the programme 🌍www.slrch.org #SLRCH2026
Collaborative project at the department of Ophthalmology.
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Can’t sleep? Tune your (internal) clock. Go outside in the middle of the day. Reduce those night time lights and midnight snacks. www.nature.com/articles/d41...
How to get the best night’s sleep: what the science says
Chuck the gadgets, the fads and the alarm. Circadian research reveals how important your body’s internal clock is to blissful slumber.
nature.com