With our research, we are one step closer to biotechnological palm oil alternatives 🌱 rdcu.be/e2nbH 📺📻 Featured on TV, radio, and online media, e.g.: www.tagesschau.de/inland/regio... #Sustainability #GreenBiotechnology #Biotechnology #SyntheticBiology #MetabolicEngineering #PalmOil #PalmOilFree

Thanks @goetheuni.bsky.social for featuring our work in fatty acid synthase engineering! A culmination of years of shared effort ✨ aktuelles.uni-frankfurt.de/english/from...

From Palm Oil to Designer Enzymes: Frankfurt Researchers Reprogram Yeast Cells | Aktuelles aus der Goethe-Universität Frankfurt

Protein Engineering Enables Sustainable Production of Industrially Important Fatty Acids Fatty acids derived from palm oil and coconut oil are found in countless everyday products, but their extractio...

aktuelles.uni-frankfurt.de

Happy to have contributed to this issue! doi.org/10.1016/j.ti...

Trends in Biochemical Sciences@cp-trendsbiochem.bsky.social · 7mo ago

🎉 It's here! Our January issue has dropped and, with it, the start of our hashtag#TIBS50 anniversary celebration! Dive into the full issue and join us as we honor five decades of publishing 👉 www.cell.com/trends/bioch... (1/n)

Short fatty acids, custom synthesized by engineered yeast 🧫 Here it is: doi.org/10.1038/s415... 🤝✨ Fantastic team effort — thanks to Yongjin Zhou! Science made possible at @goetheuni.bsky.social 🏛️🔬

New in Angewandte 🔥: With two engineered changes, we reprogram mammalian fatty acid synthase to make pyrones instead of fatty acids! 🧬 Congrats Felix, Nadja & Caro! We delete the processing part + tweak the KS pocket, even mimicking PKS-like initiation. Paper: doi.org/10.1002/anie...

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides

A multienzyme was formed and evaluated by covalently linking 4-coumarate ligase (4CL1) from Piper methysticum to a non-reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP....

doi.org

Great meeting in Shenzhen by @asm.org and SIAT! Really appreciated the microbiology insights — amazing how central microbes are to so many of today’s challenges. @vscooper.micropopbio.org @rebeleinlab.bsky.social @helgebode.bsky.social @friedrich-group.bsky.social www.greeninger-chemistry.com/

📝 Online now - the Review "Molecular mechanisms of the mammalian fatty acid cycle" from Christian Gusenda and @m-grininger.bsky.social. #FattyAcidBiosynthesis #FattyAcidSynthase #FAS #mFAS #AcylCarrierProtein #ACP Read it here 👉 authors.elsevier.com/sd/article/S...

📣 Open call for a Full Professorship (W3) in Organic Synthesis. 🌍 University Frankfurt, Germany 🗓️ Application Deadline approaching: 23rd of May Join one of Germany’s leading universities. @goetheuni.bsky.social #ScienceCareers #JobOpportunity #FacultyPosition #OrganicChemistry

Excited to share my first post on Bluesky: I’ve recently been appointed as a Professor at Goethe University Frankfurt! 🎉 The Stephan Lab will use advanced bioimaging 🔬🧫 to explore how organelles collaborate to maintain subcellular architecture and metabolism.

📢 The University of Frankfurt (Germany) is hiring a Full Professor in Organic Synthesis -->Cutting-edge research in an open, collaborative environment? Check out the call and join one of Germany’s leading research universities. #AcademicJobs #FacultyPosition www.nature.com/naturecareer...

Professor (W3) in Organic Synthesis - Frankfurt am Main, Hessen (DE) job with Johann Wolfgang Goethe-Universität Frankfurt | 12838450

Goethe University Frankfurt am Main invites applications for the position of Professor (W3) in Organic Synthesis at the Faculty of Biochemistry, Ch...

nature.com

🚗💥 Henry Ford’s car assembly line is the perfect analogy for how nature builds polyketide natural compounds. But can we rearrange nature's assembly lines to make novel polyketides? 🔬 Recent breakthroughs are promising 📖 Read my perspective on how this vision is becoming reality. rdcu.be/ei12O

Design principles imprinted by evolution

Nature Chemical Biology - Redesigning polyketide biosynthesis to either derivatize polyketides or develop new ones is highly desirable, but engineered pathways usually suffer from low product...

rdcu.be