Our Review on intramembrane proteolysis is out in @cp-trendsbiochem.bsky.social! We look at how proteases, substrates, and membranes work together to recognize and process membrane proteins. Great fun putting this together with Dönem Avci and Susi Steigleder! www.sciencedirect.com/science/arti...

The latest cover of @cp-trendsbiochem.bsky.social (TiBS) highlights work of Julieta Mateos et al, on alternative splicing in plants.🌿 Born from a chat at the 2025 edition of the meeting, the review highlights the value of attending the event. Join us next year, for our 10-year anniversary!

Is the RNA in our blood just fragile debris, or a readable record of how the body responds to disease? 🧬🩸 In our new Opinion in @cp-trendsbiochem.bsky.social, we propose a framework for cfRNA fragmentomics.

📢 Our October issue is live! Explore the latest #TIBS50 content, Reviews, and so much more 👉 www.cell.com/trends/bioch...

🔬 In the latest #TIBS50: Foundations and frontiers installment, @alessiociulli.bsky.social and co look to proximity-inducing therapeutics and how the often-underappreciated linker can shape PROTAC function and design. Read their Feature Review: www.cell.com/trends/bioch...

Science is more than the data - it’s how we communicate it. Our #TIBS50 #ThematicTriumphs turns to a series on scientific figure development, bringing together insights from 60+ authors sharing advice on creating clear, compelling figures. It's here 👉 www.sciencedirect.com/special-issu...

🎉 #TIBS50 continues with #CitedClassics: "How do plants feel the heat?" from Pierre Goloubinoff and colleagues. We’re revisiting the most-cited article from 2012 — a standout from the archive. Read it here 👉 www.sciencedirect.com/science/arti...

🌎🪨🧪Trends in Chemistry and Trends in Biochemical Sciences are seeking proposals for our joint special issue, “New Perspectives in (Bio)Geochemistry.” We welcome forward-looking Reviews and Opinions from researchers working across geochemistry. @cp-trendsbiochem.bsky.social 1/2

🌎 How does life shape Earth’s chemical cycles? From molecular mechanisms to environmental function, we’re looking for ideas that explore how core biochemical principles scale to shape biogeochemical cycles and Earth system processes. Can you bridge these scales? We want to hear from you!

Top cited in 2011: "The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation" from John Blenis and colleagues. A #CitedClassics pick from our #TIBS50 series. Read more 👉 lnkd.in/escKdJ7F

✨ Fireflies, flaming branches, dripping water, fruit, and colorful centipedes bring the dynamic regulation of RNA splicing to life in this cover art. A fairytale forest with a molecular message. Read the Review from Maciej Ciesla et al: www.cell.com/trends/bioch...

📢Our September issue is live! Explore the latest #TIBS50 content, Reviews, and so much more 👉 www.cell.com/trends/bioch...

🌍 Eight scientists, eight unique journeys, and shared values that transcend borders: curiosity, collaboration, and resilience. Read stories from Maciej Ciesla, @tomasdolezal.bsky.social, Ana Raquel Soares, David Reverter, Mirta Boban, Seyit Kale, Iva Hafner-Bratkovic, and Maryna Zlatohurska.

✂️ The molecular cutting crew is on the job! Guide RNA shows Cas9 exactly where to make the cut, capturing the targeted precision at the heart of #CRISPRCas9. Check out “CRISPR-Cas9: the molecular cutting crew,” illustrated by @vishalbharmera.bsky.social. #TIBS50 #TIBSCelebrates50

Relatedly, new review! @cp-trendsbiochem.bsky.social It's often assumed that oxygen is required for eukaryotic metabolism, but early eukaryotes emerged when oxygen was scarce. Their descendants use a remarkable diversity of anaerobic electron acceptors. Read more here: www.cell.com/trends/bioch...

Ayush Midha@ayushmidha.bsky.social · last mo.

New preprint! www.biorxiv.org/content/10.6... We uncovered surprising roles for a little-known metabolic pathway, branched-chain amino acid fermentation, with implications for hypoxia, mitochondrial dysfunction, alcohol toxicity, and fertility.

From the classroom to @cp-trendsbiochem.bsky.social 🧬✏️ Honored to be part of the #TIBS50 Scientific Sketch series! 🎨 My feature: www.sciencedirect.com/science/arti... 📖 Explore the September issue: www.cell.com/trends/bioch... #CRISPR #GenomeEditing #PlantScience

Amazing! Latest spotlight in @cp-trendsbiochem.bsky.social highlights our lab's recent work on the origins of Mo/W!!! A first for the lab, congrats, Aya and everyone! 🎉 www.cell.com/trends/bioch... Link for the original paper: www.nature.com/articles/s41...

A phylogenomic analysis of ancient transition metal biochemistry

Despite seemingly low levels of molybdenum (Mo)/tungsten (W) in the Earth’s ancient oceans, these metals play central roles in driving modern biogeochemical cycles. Klos et al. used phylogenomic appro...

cell.com

🏹 On this month's cover: Attack, defend, counterattack. In the bacterial world, survival can be a battle—and this month’s cover brings that microscopic arms race to life with a reimagining by artist (and author) Nicolas Rivard of Caspar David Friedrich’s Wanderer above the Sea of Fog.

Top cited. 2007. "Functional amyloid – from bacteria to humans" from Jeffery Kelly and colleagues. A #CitedClassics pick from our #TIBSCelebrates50 series 🎉. Read more 👉 www.sciencedirect.com/science/arti...

Proud to see our review "Anti-type VI tactics: bacterial defenses against T6SS attacks" featured on the Cover @cp-trendsbiochem.bsky.social www.cell.com/trends/bioch... Kudos to @nicrivard.bsky.social for creating this fantastic Cover illustration! But… do do you recognize the original painting?

⏲️ Last chance to be part of the #TIBSCelebrates50 #ScienceSketch series! Have a biochemistry-inspired cartoon you've been meaning to submit? Now's the time! 📅 Submit by August 31 for consideration in the special #TIBS50 collection. ℹ️ Details: www.cell.com/trends/bioch...

Our review is out in @cp-trendsbiochem.bsky.social! We discuss recent structural insights into the Nipah virus RNA polymerase and how they are improving our understanding of its mechanism. Many thanks to @haukehillen.bsky.social for the collaboration 🧬🔬 Link⬇️ ⬇️ www.sciencedirect.com/science/arti...

🎨 This month's cover (by Xi-Ao) transforms the reciprocal regulation between m6A and noncoding RNAs into a striking mountain–water landscape inspired by classical Chinese artwork. Read the Review "Reciprocal Regulation of m6A and Noncoding RNAs Across Kingdoms": www.cell.com/trends/bioch...

🧬 Sometimes proteins just need a little help getting back on their feet. Check out the most recent #TIBS50 #ScienceSketch from Yunxing (Stella) Li: www.cell.com/trends/bioch...

🎉 From Reviews to global perspectives 🌏, #ScienceSketches, and campaigns revisiting landmark TIBS papers and influential special issues, #TIBSCelebrates50 has celebrated the breadth of our community and the journal's rich history.

🌏 Biochemistry advances across borders. From returning home to build research programs, to forging international collaborations and mentoring the next generation, researchers across Asia and Oceania reflect on the experiences that have shaped their scientific journeys.

A standout Review from 2001: "Macromolecular crowding: obvious but underappreciated" from R. John Ellis. As part of #TIBS50 🎉, we're revisiting the top-cited article from each year in our #CitedClassics series. Explore it 👉 www.sciencedirect.com/science/arti...

A standout from the archives: This Special Issue on ribosomes and translation (2017) is part of our #TIBS50 #ThematicTriumphs series — revisiting influential themes from across the journal’s history. Read more 👉 www.sciencedirect.com/journal/tren...

📢 Our July issue is live! Dive into #TIBS50 content, insightful Opinions and Reviews, and more 👉 www.cell.com/trends/bioch...

📢 We're heading to @goldschmidt-confer.bsky.social! TIBS is excited to connect with the biogeochemistry community and explore emerging topics at the interface of biochemistry, microbiology, geochemistry, and environmental science!