Mycobacterium tuberculosis is an outlier in many ways. One of them is keeping a high degree of functional redundancy despite its obligate pathogen lifestyle. In this review, we reflect on the biological meaning of M. tuberculosis functional redundancies. journals.plos.org/plospathogen...

Essential redundancies fuel Mycobacterium tuberculosis adaptation to the host

Redundancy in biology is, at a glance, counterintuitive because if the function of two gene products completely overlaps then, throughout the course of evolution, one of the genes will likely accumula...

journals.plos.org

Long-chain fatty acids can be carbon sources for pathogens but are also potent antimicrobials. In our latest work, we explored the question of how Mycobacterium tuberculosis avoids getting killed by a preferred carbon source. www.biorxiv.org/content/10.1...

The Mycobacterium tuberculosis long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infection

The human pathogen Mycobacterium tuberculosis (Mtb) thrives in lipid-rich microenvironments. Long-chain fatty acids (LCFA) are some of the most abundant lipids encountered by Mtb during infection. Mtb...

biorxiv.org

The Mycobacterium tuberculosis long-chain fatty acid resistome reveals the universal stress protein TB15.3 as essential for infection https://www.biorxiv.org/content/10.1101/2025.04.14.648703v1

It was really great hosting you @oneyrolles.bsky.social! Fantastic science, great conversations, and a truly enjoyable time. Glad you had a great experience!

Olivier Neyrolles@oneyrolles.bsky.social · 2y ago

Huge thanks to @marcopsilva.bsky.social, Thales Costa and all the students for the kind invite to speak at the @i3suporto.bsky.social Student symposium! 🌟 Top-notch organization, amazing vibes, and a truly warm welcome, an unforgettable experience! 🙏 #i3Ssymposium

Huge thanks to @marcopsilva.bsky.social, Thales Costa and all the students for the kind invite to speak at the @i3suporto.bsky.social Student symposium! 🌟 Top-notch organization, amazing vibes, and a truly warm welcome, an unforgettable experience! 🙏 #i3Ssymposium

First time at #EMBOtuberculosis presenting a part of my PhD work through a flash talk and poster presentation. Great to finally meet the TB community! Incredible experience in India, with amazing science, wonderful people, and delicious food! 🇮🇳

What a great conference #EMBOtuberculosis has been! Amazing science, amazing food and a very friendly community! And it was a pleasure to share the work we’re developing at i3S U. Porto.

Introducing my wonderful team at i3S - University of Porto. PhD student @marcopsilva.bsky.social and research fellow @alexjpinto.bsky.social