The first publication of our project, which identifies altered gene expressions in the human DRG associated with neck pain. Fantastic collaboration with @tedpricethepainguy.bsky.social lab, Christoph Hofstetter from Neurosurgery, and a stellar team. urldefense.com/v3/__https:/...

Transcriptome of the human C2 dorsal root ganglia in C1-2 arthrodesis surgery: insight for neck pain

Arendt-Tranholm et al. use surgically resected sensory ganglia to investigate the mechanisms underlying chronic neck pain. They produce a molecular map of

urldefense.com

Go check out our new paper on spatial transcriptomics of human sympathetic chain ganglia! Huge thanks @saadyousuf.bsky.social and @tedpricethepainguy.bsky.social for trusting me with this awesome project.

Asta Arendt-Tranholm, @ish1789.bsky.social and others in our lab and the great team at UW led by @michelecuratolo.bsky.social latest preprint on mechanisms of neck pain in patients undergoing C1/C2 fusion surgery

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

Single-cell characterization of the human C2 dorsal root ganglion recovered from C1-2 arthrodesis surgery: implications for neck pain https://www.biorxiv.org/content/10.1101/2025.03.24.645122v1

This terrific paper led by @saadyousuf.bsky.social is now accepted for publication in Diabetes. Congrats to Saad and the team. Thanks to NIH funding that made this work possible.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 3y ago

Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decreases ISR activation in DRG neurons https://www.biorxiv.org/content/10.1101/2023.12.22.572877v1

Preprint alert: Using human microneurography protocols in PatchSeq experiments on pig DRGs we identify the molecular identity of human dermal CMi-fibers (sleeping nociceptors). We provide an integrated pig-human-more transcriptomic atlas and identify OSMR and SST as marker, backed by human expts.

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2y ago

Molecular architecture of human dermal sleeping nociceptors https://www.biorxiv.org/content/10.1101/2024.12.20.629638v1

Big congrats to Marisol Mancilla for placing third in the PhD Student Poster Competition and Art Showcase. Marisol's poster was a case study on chronic neck pain.

Link to the article: news.utdallas.edu/students-tea...

Graduate Students Showcase Range of Research, Art at Competition

Graduate students at The University of Texas at Dallas recently presented their research at the PhD Student Poster Competition and Art Showcase, an annual event that highlights research and provides s...

news.utdallas.edu

New preprint online from our lab on @medrxivpreprint.bsky.social www.medrxiv.org/content/10.1... led by Marisol Mancilla Moreno in my lab in collaboration with Michele Curatolo and Christoph Hofstetter at UW.

IGHG4 Expression in C2 Human Dorsal Root Ganglion Potentially Links B Cells to Spreading Chronic Neck Pain

Very little is known about the molecular mechanisms underlying chronic neck pain, a highly prevalent and burdensome condition. We analyzed the C2 dorsal root ganglion (DRG) of patients with neck pain ...

medrxiv.org