Did you know @iasp.bsky.social’s #GlobalYear2026 is about neuropathic pain? Listen to the newest episode of Pain Exchange, featuring President Andrew Rice, @lampertlab.bsky.social, and @neiloconnell.bsky.social speaking about the goals of the campaign and more bit.ly/49S5XsZ

We are hiring a postdoc! If you love culturing neurons and are stellar at electrophysiological characterisation and imaging of sensory neurons, then come and work with us on this cool multi-lab project!🧑‍🎓 👩‍🎓 my.corehr.com/pls/uoxrecru...

The review process will be overseen by JGP Associate Editors Teresa Giraldez (@giraldezt.bsky.social) and Jeanne Nerbonne, with Guest Editor and subject experts Angelika Lampert (@lampertlab.bsky.social), Hugues Abriel, and Rajesh Khanna (@khannalabuf.bsky.social) 👉 rupress.org/jgp/pages/ca...

Köster, @lampertlab.bsky.social et al. characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. rupress.org/jgp/article/... 📙 In #Neuroscience collection 👉 rupress.org/jgp/collecti... #SfN25

The review process will be overseen by JGP Associate Editors Teresa Giraldez (@giraldezt.bsky.social) and Jeanne Nerbonne, with Guest Editor and subject experts Angelika Lampert (@lampertlab.bsky.social), Hugues Abriel, and Rajesh Khanna (@khannalabuf.bsky.social) 👉 rupress.org/jgp/pages/ca...

⏰ Abstract deadline tomorrow! Join us in Grindelwald, Feb 4–6, 2026 Worldwide Sodium Channel Conference! Robert Stewart (Harvard) talks on Nav1.8 inhibition & new Nav blockers for pain 💥Accepted abstracts → special issue @jgp.org👉 sodiumchannelconference2026.org #WSCC26 #SodiumChannels #PainResearch

🎙️ Carol Ann Remme (Amsterdam UMC) joins #WSCC26 (Feb 4–6, 2026, Grindelwald, CH) to talk about cardiac sodium channels ❤️ and their role in cardiac physiology & disease. 🧠 Abstracts due Nov 2 🔗 sodiumchannelconference2026.org/WELCOME/ #NaV #ionchannels #cardiacphysiology #scienceconference

🎙️ José Ángel Aibar, President of the Dravet Syndrome Foundation, joins #WSCC26 (Feb 4–6, 2026, Grindelwald 🇨🇭) to talk about advancing collaboration & discovery in Dravet syndrome. 🧠 Abstracts due Nov 2 – all published in a JGP special issue! 🔗 sodiumchannelconference2026.org/WELCOME/

Voltage-gated sodium channels: Mechanisms, disease, and a growing research community. Hugues Abriel and Angelika Lampert (@lampertlab.bsky.social) introduce the Special Issue (rupress.org/jgp/search-r...) illustrating the richness and continuing momentum of this field. rupress.org/jgp/article/...

This Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. Editorial by Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...

@jgp.org Special Issue rupress.org/jgp/search-r... brings together a collection of studies that exemplify the multidimensional progress in physiology, pharmacology, & structure-function analysis of voltage-gated sodium channels. From Abriel & @lampertlab.bsky.social: rupress.org/jgp/article/...

Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.

Oksana Iamshanova@iamshanovao.bsky.social · 11mo ago

2nd #WSCC26 will take place in Grindelwald (Switzerland) 🚠 from 4th to 6th of February, 2026. 🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others. 💡 Submit abstracts by the 26th of September, 2025: lnkd.in/eDhPUVKd 💻 More info: lnkd.in/eJw9pfMz

In this Viewpoint, Hull and @lampertlab.bsky.social explore the role of metaphors in the sodium channel fast inactivation mechanism-accessible to readers without a linguistics background. rupress.org/jgp/article/... 📙 In JGP Highlights Collection 2025: rupress.org/jgp/collecti... #SGP2025

Sodium channels and clinical pain: join the finale of worldwide sodium channel seminar series by Janneke Hoeijmakers on June 24! Still not enough of Nav research? Safe the date for the 2nd ww Nav channel conference Feb 4 to 6, 26 in Grindelwald CH⛰️. www.sodiumchannelseminars.org

Journal of General Physiology@jgp.org · last yr.

Metaphors shape how we communicate & understand science, from genetic blueprints to molecular gates. Hull and @lampertlab.bsky.social‬ explore their role in the sodium channel fast inactivation mechanism-accessible to readers without a linguistics background. rupress.org/jgp/article/... #IonChannels

Very happy that our science-literature synergism resulting from the worldwide sodium channel conference #WSCC24 in Grindelwald is now out. Ever thought about how the words you are using to describe your results shape how you approach your science? I hope you enjoy reading our article!

Journal of General Physiology@jgp.org · last yr.

Using metaphorical considerations to benefit research on the sodium channel fast inactivation mechanism. New Viewpoint article from Peter Hull @fau.de‬ and Angelika Lampert @lampertlab.bsky.social @rwth.bsky.social: rupress.org/jgp/article/... #VoltageGatedNaChannels #Biophysics #IonChannels

Slow inactivation of the fast sodium channel will be the topic of our next worldwide sodium channel seminar by Shimon Marom Tuesday May 27th on "Adaptive, slow sodium channel inactivation: impacts on neuronal excitability". www.sodiumchannelseminars.org for link and infos. 🧠 🎓

happening today, Tuesday 29th of April!

Angelika Lampert@lampertlab.bsky.social · last yr.

It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel

New paper blue-torial! On the surface, it's a new ⚡Nav1.5 #channelopathy causing 🫀 familial cardiac #arrhythmia. But our story has enough plot twists to rival MK Shyamalan! www.jmcc-online.com/article/S002... 🧵 1/11

Clinical and electrophysiological characterization of a SCN5A gain-of-function mutation associated with CPVT-like arrhythmia

The present study aimed to characterize the SCN5A variant I1333V, found in five families with a history of suspected catecholaminergic polymorphic ventricular tachycardia (CPVT). SCN5A encodes the por...

jmcc-online.com

It will be turbulent in the next worldwide sodium channel seminar: @antoniospantazis.bsky.social will explain why "Even a single carbon atom matters: deadly and unexpected consequences of a Nav1.5 variant" Tuesday April 29th. Visit www.sodiumchannelseminars.org for link and infos. #sodiumchannel

Our Center is a great place to work! If you are looking for a lab technician position, please check out our posting!

Center for Advanced Pain Studies@utdpaincenter.bsky.social · last yr.

📢 We're Hiring! Join Our Team at the Center for Advanced Pain Studies! ✨ CAPS is looking for a research technician. If you are passionate about research and studying chronic pain or migraine, this is your opportunity. 🔗 Learn more and apply: UTD.link/2v7

Nav1.7 structure and severe pain: join our next worldwide sodium channel seminar on March 25th by Goragot Wisedchaisri (Seattle, US) on the “Structural basis for severe pain caused by mutations in Nav1.7” www.sodiumchannelseminars.org for link and infos. See you there! #ionchannel #WSCS

Join us in Berlin in September! It is going to be a great meeting for those of you interested in neuropathic pain, itch and related conditions! #Painresearch #PainScience 🧪🧠

International Association for the Study of Pain (IASP)@iasp.bsky.social · last yr.

Time is Running out! Submit your poster abstract for #NeuPSIG2025 and present at the leading international pain meeting in Berlin this September. Submission Deadline: 3 March bit.ly/40r4Zz5 #PainScience #Neurology

Miriam Meisler will give our next #WWSC seminar on Feb 25th. Come and discuss Nav1.6 pathophysiology in epilepsy and treatment options: "Down-regulation of SCN8A by ASO or CRISPR-i prevents seizures in a GOF model". Visit www.sodiumchannelseminar.org for info and link. See you there!

Commentary: Christian Jorgensen @jorlab123.bsky.social discusses new study from Elhanafy et al. (https://buff.ly/4haX9PQ) which shows how identical mutations in the voltage sensing domain of sodium channels can yield differential functional effects. https://buff.ly/4jpCRUD #IonChannels

Nociceptor sodium #ionchannels shape subthreshold phase, upstroke, and shoulder of action potentials | Journal of General Physiology @JGenPhysiol https://buff.ly/4hku7gH #openaccess

1/5 Are you interested in the role of Nav1.9 in AP generation? And what do all the other #sodiumchannels do in the nociceptor? In a study led by the MD student Phil Köster in the lab, we performed manual patch clamp on all Navs known to be expressed in sensory neurons. Nav1.1,2,3,5,6,7,8,9.

Journal of General Physiology@jgp.org · 2y ago

Köster, Stiehl, @lampertlab.bsky.social and colleagues characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. https://buff.ly/4hku7gH #Biophysics #Neuroscience #IonChannels

and a 3rd BOOM! for today: www.biorxiv.org/content/10.1... Again on VGNaCs. Navs enter the PROTAC era!! Well done Alex Chamessian and @robgereau.bsky.social

Small molecule-mediated targeted protein degradation of voltage-gated sodium channels involved in pain

The voltage-gated sodium channels (VGSC) NaV1.8 and NaV1.7 (NaVs) have emerged as promising and high-value targets for the development of novel, non-addictive analgesics to combat the chronic pain epi...

biorxiv.org

Köster, Stiehl, @lampertlab.bsky.social and colleagues characterize eight sodium channel subtypes relevant to #nociception and use a computer model to simulate the response of two types of nociceptive nerve fibers. https://buff.ly/4hku7gH #Biophysics #Neuroscience #IonChannels

Thank you Ted! As always quick in catching new papers - this one is actually one i am really excited about. Thread to follow.

Ted Price@tedpricethepainguy.bsky.social · 2y ago

and one more BOOM! for today: rupress.org/jgp/article/... A comprehensive look at VGNaCs in DRG neurons from @lampertlab.bsky.social and colleagues with some interesting new ideas on Nav1.9.