Ever wondered how the hippocampal cognitive map is read-out? @changmin-yu.bsky.social @zilong-ji.bsky.social with Jake & John, show that, during navigation, theta sweeps indicate remembered goal-directions (cf. current/next movements or perceptual targets) 1/2 www.nature.com/articles/s41...

All theory is wrong until verified by data. Greatly indebted to @mhyaghoubi.bsky.social, @markbrandonlab.bsky.social, @douglasresearch.bsky.social for finding the hippocampus encoding reward prediction! Grateful to my advisor @cpehlevan.bsky.social, @kempnerinstitute.bsky.social. #RL #hippocampus

Nature@nature.com · 7mo ago

Nature research paper: Predictive coding of reward in the hippocampus go.nature.com/49mB13V

I’m very happy to share the latest from my lab published in @Nature Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward. Full text here: rdcu.be/eY5nh

Fantastic work!

Desdemona Fricker@desdemonafricker.bsky.social · 7mo ago

Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌

New paper from the lab, now out in @PNASNews tinyurl.com/bdeh2bs8 - ADN neurons (head direction cells) project to MEC inhibitory cells, with a preference for VIP-expressing cells - MEC VIP cells increase cfos expression during, and are required for, a spatial memory task

How good is your place cell model? Come benchmark yours against real data - nearly 70K CA1 rate maps in various geometric shapes across weeks - collected and curated in my lab by the great @jquinnlee.bsky.social and @atkeinath.bsky.social

Quinn Lee@jquinnlee.bsky.social · last yr.

The dataset and code for our recent paper in Neuron (tinyurl.com/yc48d6vr) is online now! The data is available on Zenodo (zenodo.org/records/1486...) and code on Github (github.com/jquinnlee/ge...). Big thanks to @markbrandonlab.bsky.social and @atkeinath.bsky.social on this effort! #neuroskyence 🧠

The dataset and code for our recent paper in Neuron (tinyurl.com/yc48d6vr) is online now! The data is available on Zenodo (zenodo.org/records/1486...) and code on Github (github.com/jquinnlee/ge...). Big thanks to @markbrandonlab.bsky.social and @atkeinath.bsky.social on this effort! #neuroskyence 🧠

Congrats Dr Gilberto R Vite! 🎉🍾 Gilberto successfully defended his PhD, on the role of the thalamus in coordinating activity in the entorhinal cortex. Big thanks to his committee, Laura Colgin, @markbrandonlab.bsky.social, Stuart Trenholm, and @sylvainbaillet.bsky.social 🙏🙏

Grateful to @apnews.com for covering our recent @pnas.org article on how London taxi drivers plan routes: apnews.com/video/how-th... #neuroskyence

New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment. www.cell.com/cell-reports...

Here is the MIT Tech Review article covering the data collection linked to this new Phd Opportunity at our new International Centre for NeuroArchitecture and NeuroDesign: www.technologyreview.com/2024/09/13/1...

Neuroscientists and architects are using this enormous laboratory to make buildings better

Creating life-size simulations of the real world can reveal how we, and our minds, respond to the environments around us—and could shape the future of architecture.

technologyreview.com

Hugo Spiers@hugospiers.bsky.social · 2y ago

🚨 New funded PhD position at UCL 🚨 Funding is provided for a PhD student in our new centre to help work with Fiona Zisch & Sean Hanna to apply agent-based-modelling to analyse the crazy data set from 100+ people navigating a giant maze in PEARL. See details: www.ucl.ac.uk/bartlett/arc...

What are the brain’s “real” tuning curves? Our new preprint "SIMPL: Scalable and hassle-free optimisation of neural representations from behaviour” argues that existing techniques for latent variable discovery are lacking. We suggest a much simpl-er way to do things. 1/21🧵

Now out in Neuron! We benchmark place cell models using a massive CA1 dataset—nearly 70,000 rate maps—collected as mice explore environments with different geometries BVC models perform remarkably well, but we hope this dataset/approach becomes a resource for testing/refining place cell models

Quinn Lee@jquinnlee.bsky.social · 2y ago

Psyched that my postdoc work w @markbrandonlab.bsky.social + @atkeinath.bsky.social is now in Neuron! TL/DR: remapping in CA1 has a representational structure that is reliable across brains, and we use this representation to test models of cognitive maps. #NeuroSky #NeuroAI 🧪🧠 tinyurl.com/4juhmad8