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Mark Gorelik

@markgrg.bsky.social

Postdoc in the Dantas Lab, sequencing DNA and RNA

1 Posts107 Follower906 Folgt
Oliver Meacock@olimeacock.bsky.social · 4mo ago

Delighted to see this out in its final form! doi.org/10.1093/isme... We established a discussion group focussed on the history of community ecology and how it informs our understanding of microbiota. This review distils those discussions to provide a guide for microbiologists entering the field

A microbiologist’s field guide to community ecology

Abstract. Many microbiological outcomes are shaped by the determinants of community composition, including the factors that allow pathogens to invade healt

doi.org

Gang Fang@gangfang.bsky.social · 4mo ago

Glad that our paper is out today in @cp-cellhostmicrobe.bsky.social A baby received a routine course of amoxicillin. In that infant's #gut 💩, we could see something remarkable, already present **before** the antibiotic arriveda single strain 🦠 of #Akkermansia muciniphila was already running 1/n

Epigenetic phase variation in the gut microbiome enhances bacterial adaptation

Ni et al. show that epigenetic phase variation (ePV)—gene expression changes mediated by bacterial DNA methylation—is prevalent in the human gut microbiome and associated with fluctuating environments...

cell.com

Nature Microbiology@natmicrobiol.nature.com · 6mo ago

Out Now! Spatial transcriptomics maps host–gut microbiome biogeography at high resolution #MicroSky

Spatial transcriptomics maps host–gut microbiome biogeography at high resolution

Nature Microbiology, Published online: 06 March 2026; doi:10.1038/s41564-026-02286-7Bulk polyadenylation improves the capture of microbial RNA, enabling host–microorganism interactions to be visualized at a high resolution when combined with commercially available spatial transcriptomics platforms.

go.nature.com

Nature Microbiology@natmicrobiol.nature.com · 7mo ago

Out Now! Gut bacteria ammonia production restores acetylcholine neurotransmission and bowel motility #MicroSky

Gut bacteria ammonia production restores acetylcholine neurotransmission and bowel motility

Nature Microbiology, Published online: 26 February 2026; doi:10.1038/s41564-026-02292-9Acetylcholine levels are reduced in gut dysmotility conditions. We find that gut acetylcholine levels induce a compensatory increase in gut microbiota urease activity and ammonia production. By upregulating presynaptic Cav2.1 calcium channels in enteric neurons, ammonia enhances calcium influx and restores acetylcholine release neurotransmission, revealing a microbiota-driven mechanism that preserves gut motility.

go.nature.com

Nature Reviews Microbiology@natrevmicro.nature.com · 2y ago

New online! Interactions and evolutionary relationships among bacterial mobile genetic elements

Interactions and evolutionary relationships among bacterial mobile genetic elements

Nature Reviews Microbiology, Published online: 11 March 2025; doi:10.1038/s41579-025-01157-yIn this Review, Lang and colleagues present an overview of the current knowledge landscape regarding mobile genetic elements in bacteria, with a focus on their…

nature.com